These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
6. Importance of neonatal FcR in regulating the serum half-life of therapeutic proteins containing the Fc domain of human IgG1: a comparative study of the affinity of monoclonal antibodies and Fc-fusion proteins to human neonatal FcR. Suzuki T; Ishii-Watabe A; Tada M; Kobayashi T; Kanayasu-Toyoda T; Kawanishi T; Yamaguchi T J Immunol; 2010 Feb; 184(4):1968-76. PubMed ID: 20083659 [TBL] [Abstract][Full Text] [Related]
7. Renal FcRn reclaims albumin but facilitates elimination of IgG. Sarav M; Wang Y; Hack BK; Chang A; Jensen M; Bao L; Quigg RJ J Am Soc Nephrol; 2009 Sep; 20(9):1941-52. PubMed ID: 19661163 [TBL] [Abstract][Full Text] [Related]
8. The proximal tubule and albuminuria: really! Dickson LE; Wagner MC; Sandoval RM; Molitoris BA J Am Soc Nephrol; 2014 Mar; 25(3):443-53. PubMed ID: 24408874 [TBL] [Abstract][Full Text] [Related]
9. Differential trafficking of albumin and IgG facilitated by the neonatal Fc receptor in podocytes in vitro and in vivo. Dylewski J; Dobrinskikh E; Lewis L; Tonsawan P; Miyazaki M; Jat PS; Blaine J PLoS One; 2019; 14(2):e0209732. PubMed ID: 30811433 [TBL] [Abstract][Full Text] [Related]
10. Protein glycation: effects upon protein recognition by the proximal tubule. Kowluru A; Kowluru RA; Solomon S; Martinez L Life Sci; 1992; 50(4):281-6. PubMed ID: 1732700 [TBL] [Abstract][Full Text] [Related]
11. FcRn binding properties of an abnormal truncated analbuminemic albumin variant. Andersen JT; Daba MB; Sandlie I Clin Biochem; 2010 Mar; 43(4-5):367-72. PubMed ID: 20006594 [TBL] [Abstract][Full Text] [Related]
12. Interaction with both domain I and III of albumin is required for optimal pH-dependent binding to the neonatal Fc receptor (FcRn). Sand KM; Bern M; Nilsen J; Dalhus B; Gunnarsen KS; Cameron J; Grevys A; Bunting K; Sandlie I; Andersen JT J Biol Chem; 2014 Dec; 289(50):34583-94. PubMed ID: 25344603 [TBL] [Abstract][Full Text] [Related]
13. Direct demonstration of a neonatal Fc receptor (FcRn)-driven endosomal sorting pathway for cellular recycling of albumin. Schmidt EGW; Hvam ML; Antunes F; Cameron J; Viuff D; Andersen B; Kristensen NN; Howard KA J Biol Chem; 2017 Aug; 292(32):13312-13322. PubMed ID: 28637874 [TBL] [Abstract][Full Text] [Related]
14. Generation of a double transgenic humanized neonatal Fc receptor (FcRn)/albumin mouse to study the pharmacokinetics of albumin-linked drugs. Viuff D; Antunes F; Evans L; Cameron J; Dyrnesli H; Thue Ravn B; Stougaard M; Thiam K; Andersen B; Kjærulff S; Howard KA J Control Release; 2016 Feb; 223():22-30. PubMed ID: 26699424 [TBL] [Abstract][Full Text] [Related]
15. Half-life extension of efficiently produced DARPin serum albumin fusions as a function of FcRn affinity and recycling. Merten H; Brandl F; Zimmermann M; Schaefer JV; Irpinio L; Sand KMK; Nilsen J; Andersen JT; Zangemeister-Wittke U; Plückthun A Eur J Pharm Biopharm; 2021 Oct; 167():104-113. PubMed ID: 34303832 [TBL] [Abstract][Full Text] [Related]
16. Cross-species binding analyses of mouse and human neonatal Fc receptor show dramatic differences in immunoglobulin G and albumin binding. Andersen JT; Daba MB; Berntzen G; Michaelsen TE; Sandlie I J Biol Chem; 2010 Feb; 285(7):4826-36. PubMed ID: 20018855 [TBL] [Abstract][Full Text] [Related]
17. Extending half-life by indirect targeting of the neonatal Fc receptor (FcRn) using a minimal albumin binding domain. Andersen JT; Pehrson R; Tolmachev V; Daba MB; Abrahmsén L; Ekblad C J Biol Chem; 2011 Feb; 286(7):5234-41. PubMed ID: 21138843 [TBL] [Abstract][Full Text] [Related]
18. Qualification of a homogeneous cell-based neonatal Fc receptor (FcRn) binding assay and its application to studies on Fc functionality of IgG-based therapeutics. Mathur A; Arora T; Liu L; Crouse-Zeineddini J; Mukku V J Immunol Methods; 2013 Apr; 390(1-2):81-91. PubMed ID: 23384837 [TBL] [Abstract][Full Text] [Related]
19. The X-Ray Crystallographic Structure of the Human Neonatal Fc Receptor at Acidic pH Gives Insights into pH-Dependent Conformational Changes. Taha M; Ward SE; Nam HJ Protein Pept Lett; 2016; 23(6):525-9. PubMed ID: 27041699 [TBL] [Abstract][Full Text] [Related]
20. Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn Mester S; Evers M; Meyer S; Nilsen J; Greiff V; Sandlie I; Leusen J; Andersen JT MAbs; 2021; 13(1):1893888. PubMed ID: 33691596 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]