286 related articles for article (PubMed ID: 26890856)
1. A novel dual lock method for down-regulation of genes, in which a target mRNA is captured at 2 independent positions by linked locked nucleic acid antisense oligonucleotides.
Takata R; Makado G; Kitamura A; Watanabe H; Wada T
RNA Biol; 2016; 13(3):279-89. PubMed ID: 26890856
[TBL] [Abstract][Full Text] [Related]
2. Antisense inhibition of gene expression in cells by oligonucleotides incorporating locked nucleic acids: effect of mRNA target sequence and chimera design.
Braasch DA; Liu Y; Corey DR
Nucleic Acids Res; 2002 Dec; 30(23):5160-7. PubMed ID: 12466540
[TBL] [Abstract][Full Text] [Related]
3. The intratracheal administration of locked nucleic acid containing antisense oligonucleotides induced gene silencing and an immune-stimulatory effect in the murine lung.
Uemura Y; Hagiwara K; Kobayashi K
PLoS One; 2017; 12(11):e0187286. PubMed ID: 29107995
[TBL] [Abstract][Full Text] [Related]
4. A structure-activity study of the inhibition of HIV-1 Tat-dependent trans-activation by mixmer 2'-O-methyl oligoribonucleotides containing locked nucleic acid (LNA), alpha-L-LNA, or 2'-thio-LNA residues.
Arzumanov A; Stetsenko DA; Malakhov AD; Reichelt S; Sørensen MD; Babu BR; Wengel J; Gait MJ
Oligonucleotides; 2003; 13(6):435-53. PubMed ID: 15025911
[TBL] [Abstract][Full Text] [Related]
5. Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts.
Burel SA; Hart CE; Cauntay P; Hsiao J; Machemer T; Katz M; Watt A; Bui HH; Younis H; Sabripour M; Freier SM; Hung G; Dan A; Prakash TP; Seth PP; Swayze EE; Bennett CF; Crooke ST; Henry SP
Nucleic Acids Res; 2016 Mar; 44(5):2093-109. PubMed ID: 26553810
[TBL] [Abstract][Full Text] [Related]
6. An Investigation into the Potential of Targeting
Goddard LR; Mardle CE; Gneid H; Ball CG; Gowers DM; Atkins HS; Butt LE; Watts JK; Vincent HA; Callaghan AJ
Molecules; 2021 Jun; 26(11):. PubMed ID: 34200016
[TBL] [Abstract][Full Text] [Related]
7. Quantitative fluorescence imaging determines the absolute number of locked nucleic acid oligonucleotides needed for suppression of target gene expression.
Buntz A; Killian T; Schmid D; Seul H; Brinkmann U; Ravn J; Lindholm M; Knoetgen H; Haucke V; Mundigl O
Nucleic Acids Res; 2019 Jan; 47(2):953-969. PubMed ID: 30462278
[TBL] [Abstract][Full Text] [Related]
8. Antisense locked nucleic acid gapmers to control Candida albicans filamentation.
Araújo D; Mil-Homens D; Rodrigues ME; Henriques M; Jørgensen PT; Wengel J; Silva S
Nanomedicine; 2022 Jan; 39():102469. PubMed ID: 34606999
[TBL] [Abstract][Full Text] [Related]
9. Nuclear antisense effects in cyclophilin A pre-mRNA splicing by oligonucleotides: a comparison of tricyclo-DNA with LNA.
Ittig D; Liu S; Renneberg D; Schümperli D; Leumann CJ
Nucleic Acids Res; 2004; 32(1):346-53. PubMed ID: 14726483
[TBL] [Abstract][Full Text] [Related]
10. Sphingosine kinase 1 is a relevant molecular target in gastric cancer.
Fuereder T; Hoeflmayer D; Jaeger-Lansky A; Rasin-Streden D; Strommer S; Fisker N; Hansen BJ; Crevenna R; Wacheck V
Anticancer Drugs; 2011 Mar; 22(3):245-52. PubMed ID: 21360847
[TBL] [Abstract][Full Text] [Related]
11. Direct isolation of poly(A)+ RNA from 4 M guanidine thiocyanate-lysed cell extracts using locked nucleic acid-oligo(T) capture.
Jacobsen N; Nielsen PS; Jeffares DC; Eriksen J; Ohlsson H; Arctander P; Kauppinen S
Nucleic Acids Res; 2004 Apr; 32(7):e64. PubMed ID: 15096560
[TBL] [Abstract][Full Text] [Related]
12. A functionally improved locked nucleic acid antisense oligonucleotide inhibits Bcl-2 and Bcl-xL expression and facilitates tumor cell apoptosis.
Simões-Wüst AP; Hopkins-Donaldson S; Sigrist B; Belyanskaya L; Stahel RA; Zangemeister-Wittke U
Oligonucleotides; 2004; 14(3):199-209. PubMed ID: 15625915
[TBL] [Abstract][Full Text] [Related]
13. Downregulation of p21(WAF1/CIP1) and estrogen receptor alpha in MCF-7 cells by antisense oligonucleotides containing locked nucleic acid (LNA).
Jepsen JS; Pfundheller HM; Lykkesfeldt AE
Oligonucleotides; 2004; 14(2):147-56. PubMed ID: 15294077
[TBL] [Abstract][Full Text] [Related]
14. Transcription factor decoy oligonucleotides modified with locked nucleic acids: an in vitro study to reconcile biostability with binding affinity.
Crinelli R; Bianchi M; Gentilini L; Palma L; Sørensen MD; Bryld T; Babu RB; Arar K; Wengel J; Magnani M
Nucleic Acids Res; 2004; 32(6):1874-85. PubMed ID: 15051810
[TBL] [Abstract][Full Text] [Related]
15. Phospholamban Inhibition by a Single Dose of Locked Nucleic Acid Antisense Oligonucleotide Improves Cardiac Contractility in Pressure Overload-Induced Systolic Dysfunction in Mice.
Morihara H; Yamamoto T; Oiwa H; Tonegawa K; Tsuchiyama D; Kawakatsu I; Obana M; Maeda M; Mohri T; Obika S; Fujio Y; Nakayama H
J Cardiovasc Pharmacol Ther; 2017 May; 22(3):273-282. PubMed ID: 27811197
[TBL] [Abstract][Full Text] [Related]
16. Knockdown of Long Noncoding RNA Plasmacytoma Variant Translocation 1 with Antisense Locked Nucleic Acid GapmeRs Exerts Tumor-Suppressive Functions in Human Acute Erythroleukemia Cells Through Downregulation of
Salehi M; Sharifi M; Bagheri M
Cancer Biother Radiopharm; 2019 Aug; 34(6):371-379. PubMed ID: 30141968
[No Abstract] [Full Text] [Related]
17. Activation of prokaryotic translation by antisense oligonucleotides binding to coding region of mRNA.
Hayashi G; Hong C; Hagihara M; Nakatani K
Biochem Biophys Res Commun; 2012 Dec; 429(1-2):105-10. PubMed ID: 23111330
[TBL] [Abstract][Full Text] [Related]
18. A novel integrated strategy (full length gene targeting) for mRNA accessible site tagging combined with microarray hybridization/RNase H cleavage to screen effective antisense oligonucleotides.
Sun Y; Duan M; Lin R; Wang D; Li C; Bo X; Wang S
Mol Vis; 2006 Nov; 12():1364-71. PubMed ID: 17149362
[TBL] [Abstract][Full Text] [Related]
19. Non-hybridization saturable mechanisms play a role in the uptake of (68)Ga-Labeled LNA-DNA mixmer antisense oligonucleotides in rats.
Lendvai G; Monazzam A; Velikyan I; Eriksson B; Josephsson R; Långström B; Bergström M; Estrada S
Oligonucleotides; 2009 Sep; 19(3):223-32. PubMed ID: 19732020
[TBL] [Abstract][Full Text] [Related]
20. Hsp90 protein interacts with phosphorothioate oligonucleotides containing hydrophobic 2'-modifications and enhances antisense activity.
Liang XH; Shen W; Sun H; Kinberger GA; Prakash TP; Nichols JG; Crooke ST
Nucleic Acids Res; 2016 May; 44(8):3892-907. PubMed ID: 26945041
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
