BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

139 related articles for article (PubMed ID: 26891146)

  • 1. Rapid induction of apoptosis in chronic lymphocytic leukemia cells by the microtubule disrupting agent BNC105.
    Bates D; Feris EJ; Danilov AV; Eastman A
    Cancer Biol Ther; 2016; 17(3):291-9. PubMed ID: 26891146
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Vinblastine rapidly induces NOXA and acutely sensitizes primary chronic lymphocytic leukemia cells to ABT-737.
    Bates DJ; Danilov AV; Lowrey CH; Eastman A
    Mol Cancer Ther; 2013 Aug; 12(8):1504-14. PubMed ID: 23723123
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The novel tubulin-targeting agent pyrrolo-1,5-benzoxazepine-15 induces apoptosis in poor prognostic subgroups of chronic lymphocytic leukemia.
    McElligott AM; Maginn EN; Greene LM; McGuckin S; Hayat A; Browne PV; Butini S; Campiani G; Catherwood MA; Vandenberghe E; Williams DC; Zisterer DM; Lawler M
    Cancer Res; 2009 Nov; 69(21):8366-75. PubMed ID: 19826055
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Induction of apoptosis in leukemic cells by the reversible microtubule-disrupting agent 2-methoxy-5-(2',3',4'-trimethoxyphenyl)-2,4,6-cycloheptatrien-1 -one: protection by Bcl-2 and Bcl-X(L) and cell cycle arrest.
    Gajate C; Barasoain I; Andreu JM; Mollinedo F
    Cancer Res; 2000 May; 60(10):2651-9. PubMed ID: 10825137
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel Benzo[B]Furans with Anti-Microtubule Activity Upregulate Expression of Apoptotic Genes and Arrest Leukemia Cells in G2/M Phase.
    Królewska-Golińska K; Cieślak MJ; Sobczak M; Dolot R; Radzikowska-Cieciura E; Napiórkowska M; Wybrańska I; Nawrot B
    Anticancer Agents Med Chem; 2019; 19(3):375-388. PubMed ID: 30465514
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cyclin-Dependent Kinase Inhibitor P1446A Induces Apoptosis in a JNK/p38 MAPK-Dependent Manner in Chronic Lymphocytic Leukemia B-Cells.
    Paiva C; Godbersen JC; Soderquist RS; Rowland T; Kilmarx S; Spurgeon SE; Brown JR; Srinivasa SP; Danilov AV
    PLoS One; 2015; 10(11):e0143685. PubMed ID: 26606677
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The vascular disrupting agent BNC105 potentiates the efficacy of VEGF and mTOR inhibitors in renal and breast cancer.
    Inglis DJ; Lavranos TC; Beaumont DM; Leske AF; Brown CK; Hall AJ; Kremmidiotis G
    Cancer Biol Ther; 2014; 15(11):1552-60. PubMed ID: 25482941
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Benzylamide sulindac analogues induce changes in cell shape, loss of microtubules and G(2)-M arrest in a chronic lymphocytic leukemia (CLL) cell line and apoptosis in primary CLL cells.
    Moon EY; Lerner A
    Cancer Res; 2002 Oct; 62(20):5711-9. PubMed ID: 12384529
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Distinct signaling pathways of microtubule inhibitors--vinblastine and Taxol induce JNK-dependent cell death but through AP-1-dependent and AP-1-independent mechanisms, respectively.
    Kolomeichuk SN; Terrano DT; Lyle CS; Sabapathy K; Chambers TC
    FEBS J; 2008 Apr; 275(8):1889-99. PubMed ID: 18341588
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Vinblastine induces acute, cell cycle phase-independent apoptosis in some leukemias and lymphomas and can induce acute apoptosis in others when Mcl-1 is suppressed.
    Salerni BL; Bates DJ; Albershardt TC; Lowrey CH; Eastman A
    Mol Cancer Ther; 2010 Apr; 9(4):791-802. PubMed ID: 20371726
    [TBL] [Abstract][Full Text] [Related]  

  • 11. c-Jun N-terminal kinase mediates microtubule-depolymerizing agent-induced microtubule depolymerization and G2/M arrest in MCF-7 breast cancer cells.
    Chen J; Sun WL; Wasylyk B; Wang YP; Zheng H
    Anticancer Drugs; 2012 Jan; 23(1):98-107. PubMed ID: 21968419
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Aspirin induces apoptosis in human leukemia cells independently of NF-kappaB and MAPKs through alteration of the Mcl-1/Noxa balance.
    Iglesias-Serret D; Piqué M; Barragán M; Cosialls AM; Santidrián AF; González-Gironès DM; Coll-Mulet L; de Frias M; Pons G; Gil J
    Apoptosis; 2010 Feb; 15(2):219-29. PubMed ID: 19936928
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Vincristine activates c-Jun N-terminal kinase in chronic lymphocytic leukaemia in vivo.
    Bates DJ; Lewis LD; Eastman A; Danilov AV
    Br J Clin Pharmacol; 2015 Sep; 80(3):493-501. PubMed ID: 25753324
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Leukaemic cells from chronic lymphocytic leukaemia patients undergo apoptosis following microtubule depolymerization and Lyn inhibition by nocodazole.
    Frezzato F; Trimarco V; Martini V; Gattazzo C; Ave E; Visentin A; Cabrelle A; Olivieri V; Zambello R; Facco M; Zonta F; Cristiani A; Brunati AM; Moro S; Semenzato G; Trentin L
    Br J Haematol; 2014 Jun; 165(5):659-72. PubMed ID: 24606526
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Induction of B-chronic lymphocytic leukemia cell apoptosis by arsenic trioxide involves suppression of the phosphoinositide 3-kinase/Akt survival pathway via c-jun-NH2 terminal kinase activation and PTEN upregulation.
    Redondo-Muñoz J; Escobar-Díaz E; Hernández Del Cerro M; Pandiella A; Terol MJ; García-Marco JA; García-Pardo A
    Clin Cancer Res; 2010 Sep; 16(17):4382-91. PubMed ID: 20534739
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of 7-hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a tubulin polymerization inhibitor with potent antiproliferative and tumor vascular disrupting properties.
    Flynn BL; Gill GS; Grobelny DW; Chaplin JH; Paul D; Leske AF; Lavranos TC; Chalmers DK; Charman SA; Kostewicz E; Shackleford DM; Morizzi J; Hamel E; Jung MK; Kremmidiotis G
    J Med Chem; 2011 Sep; 54(17):6014-27. PubMed ID: 21774499
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of extracellular signal-regulated kinase (ERK) mediates cell cycle phase independent apoptosis in vinblastine-treated ML-1 cells.
    Stadheim TA; Xiao H; Eastman A
    Cancer Res; 2001 Feb; 61(4):1533-40. PubMed ID: 11245462
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Modulation of mitogen-activated protein kinases and phosphorylation of Bcl-2 by vinblastine represent persistent forms of normal fluctuations at G2-M1.
    Fan M; Du L; Stone AA; Gilbert KM; Chambers TC
    Cancer Res; 2000 Nov; 60(22):6403-7. PubMed ID: 11103805
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Induction of apoptosis by the garlic-derived compound S-allylmercaptocysteine (SAMC) is associated with microtubule depolymerization and c-Jun NH(2)-terminal kinase 1 activation.
    Xiao D; Pinto JT; Soh JW; Deguchi A; Gundersen GG; Palazzo AF; Yoon JT; Shirin H; Weinstein IB
    Cancer Res; 2003 Oct; 63(20):6825-37. PubMed ID: 14583480
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An oral quinoline derivative, MPT0B392, causes leukemic cells mitotic arrest and overcomes drug resistant cancer cells.
    Chao MW; Huang HL; HuangFu WC; Hsu KC; Liu YM; Wu YW; Lin CF; Chen YL; Lai MJ; Lee HY; Liou JP; Teng CM; Yang CR
    Oncotarget; 2017 Apr; 8(17):27772-27785. PubMed ID: 28186963
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.