These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

80 related articles for article (PubMed ID: 2690587)

  • 1. Biochemistry of renin.
    Kokubu T; Hiwada K; Murakami E; Muneta S
    Adv Exp Med Biol; 1989; 247A():19-24. PubMed ID: 2690587
    [No Abstract]   [Full Text] [Related]  

  • 2. The P1N-isopropyl motif bearing hydroxyethylene dipeptide isostere analogues of aliskiren are in vitro potent inhibitors of the human aspartyl protease renin.
    Yamaguchi Y; Menear K; Cohen NC; Mah R; Cumin F; Schnell C; Wood JM; Maibaum J
    Bioorg Med Chem Lett; 2009 Aug; 19(16):4863-7. PubMed ID: 19615901
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Conversion between renin and high-molecular-weight renin in the dog.
    Funakawa S; Funae Y; Yamamoto K
    Biochem J; 1978 Dec; 176(3):977-81. PubMed ID: 747665
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NEW RENIN-INHIBITORS--STABILITY AND ACTIVITY DETERMINATION. PART III.
    Marszałek D; Goldnik A; Winiecka I; Jaworski P; Mazurek AP
    Acta Pol Pharm; 2016; 73(2):329-36. PubMed ID: 27180425
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Renin inhibitors inhibited the activity of recombinant human renin but not activity in healthy human plasma.
    Iwai M; Senba I; Kanno H; Nakaoka H; Inaba S; Horiuchi M
    Clin Lab; 2012; 58(3-4):291-8. PubMed ID: 22582503
    [TBL] [Abstract][Full Text] [Related]  

  • 6. NEW RENIN INHIBITORS - STABILITY AND ACTIVITY DETERMINATION. PART IV.
    Marszalek D; Goldnik A; Winiecka I; Jaworsk P; Mazurek Aleksander P
    Acta Pol Pharm; 2017 Mar; 74(2):393-399. PubMed ID: 29624244
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design and synthesis of potent macrocyclic renin inhibitors.
    Sund C; Belda O; Wiktelius D; Sahlberg C; Vrang L; Sedig S; Hamelink E; Henderson I; Agback T; Jansson K; Borkakoti N; Derbyshire D; Eneroth A; Samuelsson B
    Bioorg Med Chem Lett; 2011 Jan; 21(1):358-62. PubMed ID: 21112780
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design of a well-absorbed renin inhibitor.
    Rosenberg SH; Kleinert HD; Stein HH; Martin DL; Chekal MA; Cohen J; Egan DA; Tricarico KA; Baker WR
    J Med Chem; 1991 Jan; 34(1):469-71. PubMed ID: 1992151
    [No Abstract]   [Full Text] [Related]  

  • 9. Novel approach of fragment-based lead discovery applied to renin inhibitors.
    Tawada M; Suzuki S; Imaeda Y; Oki H; Snell G; Behnke CA; Kondo M; Tarui N; Tanaka T; Kuroita T; Tomimoto M
    Bioorg Med Chem; 2016 Nov; 24(22):6066-6074. PubMed ID: 27720325
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The discovery and synthesis of potent zwitterionic inhibitors of renin.
    Aspiotis R; Chen A; Cauchon E; Dubé D; Falgueyret JP; Gagné S; Gallant M; Grimm EL; Houle R; Juteau H; Lacombe P; Laliberté S; Lévesque JF; MacDonald D; McKay D; Percival MD; Roy P; Soisson SM; Wu T
    Bioorg Med Chem Lett; 2011 Apr; 21(8):2430-6. PubMed ID: 21429746
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of renin inhibitors containing a simple aspartate binding moiety that imparts reduced P450 inhibition.
    Lawhorn BG; Tran T; Hong VS; Morgan LA; Le BT; Harpel MR; Jolivette L; Diaz E; Schwartz B; Gross JW; Tomaszek T; Semus S; Concha N; Smallwood A; Holt DA; Kallander LS
    Bioorg Med Chem Lett; 2017 Nov; 27(21):4838-4843. PubMed ID: 28985999
    [TBL] [Abstract][Full Text] [Related]  

  • 12. trans-(3S,4S)-Disubstituted pyrrolidines as inhibitors of the human aspartyl protease renin. Part I: prime site exploration using an amino linker.
    Lorthiois E; Cumin F; Ehrhardt C; Kosaka T; Sellner H; Ostermann N; Francotte E; Wagner T; Maibaum J
    Bioorg Med Chem Lett; 2015 Apr; 25(8):1782-1786. PubMed ID: 25782742
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Renin inhibitors for the treatment of hypertension: design and optimization of a novel series of spirocyclic piperidines.
    Chen A; Aspiotis R; Campeau LC; Cauchon E; Chefson A; Ducharme Y; Falgueyret JP; Gagné S; Han Y; Houle R; Laliberté S; Larouche G; Lévesque JF; McKay D; Percival D
    Bioorg Med Chem Lett; 2011 Dec; 21(24):7399-404. PubMed ID: 22071301
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The occurrence of renin inhibitor in rice: isolation, identification, and structure-function relationship.
    Takahashi S; Tokiwano T; Hata K; Kodama I; Hokari M; Suzuki N; Yoshizawa Y; Gotoh T
    Biosci Biotechnol Biochem; 2010; 74(8):1713-5. PubMed ID: 20699562
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hemodynamic effects of renin inhibitors.
    Kleinert HD
    Am J Nephrol; 1996; 16(3):252-60. PubMed ID: 8739885
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lead optimization of 5-amino-6-(2,2-dimethyl-5-oxo-4-phenylpiperazin-1-yl)-4-hydroxyhexanamides to reduce a cardiac safety issue: discovery of DS-8108b, an orally active renin inhibitor.
    Nakamura Y; Fujimoto T; Ogawa Y; Namiki H; Suzuki S; Asano M; Sugita C; Mochizuki A; Miyazaki S; Tamaki K; Nagai Y; Inoue S; Nagayama T; Kato M; Chiba K; Takasuna K; Nishi T
    Bioorg Med Chem; 2013 Jun; 21(11):3175-96. PubMed ID: 23598247
    [TBL] [Abstract][Full Text] [Related]  

  • 17. trans-3,4-Disubstituted pyrrolidines as inhibitors of the human aspartyl protease renin. Part II: prime site exploration using an oxygen linker.
    Sellner H; Cottens S; Cumin F; Ehrhardt C; Kosaka T; Lorthiois E; Ostermann N; Webb RL; Rigel DF; Wagner T; Maibaum J
    Bioorg Med Chem Lett; 2015 Apr; 25(8):1787-1791. PubMed ID: 25754490
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comprehending renin inhibitor's binding affinity using structure-based approaches.
    Subramanian G; Rao SN
    Bioorg Med Chem Lett; 2013 Dec; 23(24):6667-72. PubMed ID: 24239018
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Practical synthesis of a renin inhibitor via a diastereoselective Dieckmann cyclization.
    Gauvreau D; Hughes GJ; Lau SY; McKay DJ; O'Shea PD; Sidler RR; Yu B; Davies IW
    Org Lett; 2010 Nov; 12(22):5146-9. PubMed ID: 20945851
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and optimization of novel (3S,5R)-5-(2,2-dimethyl-5-oxo-4-phenylpiperazin-1-yl)piperidine-3-carboxamides as orally active renin inhibitors.
    Mori Y; Ogawa Y; Mochizuki A; Nakamura Y; Fujimoto T; Sugita C; Miyazaki S; Tamaki K; Nagayama T; Nagai Y; Inoue S; Chiba K; Nishi T
    Bioorg Med Chem; 2013 Sep; 21(18):5907-22. PubMed ID: 23886807
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.