These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 26907161)

  • 1. Structures of Trypanosome Vacuolar Soluble Pyrophosphatases: Antiparasitic Drug Targets.
    Yang Y; Ko TP; Chen CC; Huang G; Zheng Y; Liu W; Wang I; Ho MR; Hsu ST; O'Dowd B; Huff HC; Huang CH; Docampo R; Oldfield E; Guo RT
    ACS Chem Biol; 2016 May; 11(5):1362-71. PubMed ID: 26907161
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Macromolecular Targets of Antiparasitic Germacranolide Sesquiterpenoids: An
    Arnston PM; Setzer WN
    Comb Chem High Throughput Screen; 2020; 23(6):477-503. PubMed ID: 32067612
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design and preparation of sterol mimetics as potential antiparasitics.
    Gigante F; Kaiser M; Brun R; Gilbert IH
    Bioorg Med Chem; 2010 Oct; 18(20):7291-301. PubMed ID: 20846867
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural and Functional Highlights of Vacuolar Soluble Protein 1 from Pathogen Trypanosoma brucei brucei.
    Jamwal A; Round AR; Bannwarth L; Venien-Bryan C; Belrhali H; Yogavel M; Sharma A
    J Biol Chem; 2015 Dec; 290(51):30498-513. PubMed ID: 26494625
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sterol 14alpha-demethylase (CYP51) as a therapeutic target for human trypanosomiasis and leishmaniasis.
    Lepesheva GI; Waterman MR
    Curr Top Med Chem; 2011; 11(16):2060-71. PubMed ID: 21619513
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bisphosphonate inhibition of the exopolyphosphatase activity of the Trypanosoma brucei soluble vacuolar pyrophosphatase.
    Kotsikorou E; Song Y; Chan JM; Faelens S; Tovian Z; Broderick E; Bakalara N; Docampo R; Oldfield E
    J Med Chem; 2005 Sep; 48(19):6128-39. PubMed ID: 16162013
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 2-alkylaminoethyl-1,1-bisphosphonic acids are potent inhibitors of the enzymatic activity of Trypanosoma cruzi squalene synthase.
    Rodrígues-Poveda CA; González-Pacanowska D; Szajnman SH; Rodríguez JB
    Antimicrob Agents Chemother; 2012 Aug; 56(8):4483-6. PubMed ID: 22585217
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Applicability of plant-based products in the treatment of Trypanosoma cruzi and Trypanosoma brucei infections: a systematic review of preclinical in vivo evidence.
    Pereira RM; Greco GMZ; Moreira AM; Chagas PF; Caldas IS; Gonçalves RV; Novaes RD
    Parasitology; 2017 Sep; 144(10):1275-1287. PubMed ID: 28578742
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Vinyl sulfones as antiparasitic agents and a structural basis for drug design.
    Kerr ID; Lee JH; Farady CJ; Marion R; Rickert M; Sajid M; Pandey KC; Caffrey CR; Legac J; Hansell E; McKerrow JH; Craik CS; Rosenthal PJ; Brinen LS
    J Biol Chem; 2009 Sep; 284(38):25697-703. PubMed ID: 19620707
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bisphosphonate-Based Molecules as Potential New Antiparasitic Drugs.
    Branco Santos JC; de Melo JA; Maheshwari S; de Medeiros WMTQ; de Freitas Oliveira JW; Moreno CJ; Mario Amzel L; Gabelli SB; Sousa Silva M
    Molecules; 2020 Jun; 25(11):. PubMed ID: 32503272
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Toward the development of dual-targeted glyceraldehyde-3-phosphate dehydrogenase/trypanothione reductase inhibitors against Trypanosoma brucei and Trypanosoma cruzi.
    Belluti F; Uliassi E; Veronesi G; Bergamini C; Kaiser M; Brun R; Viola A; Fato R; Michels PA; Krauth-Siegel RL; Cavalli A; Bolognesi ML
    ChemMedChem; 2014 Feb; 9(2):371-82. PubMed ID: 24403089
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei bound to the antifungal drugs posaconazole and fluconazole.
    Chen CK; Leung SS; Guilbert C; Jacobson MP; McKerrow JH; Podust LM
    PLoS Negl Trop Dis; 2010 Apr; 4(4):e651. PubMed ID: 20386598
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
    Koh CY; Siddaramaiah LK; Ranade RM; Nguyen J; Jian T; Zhang Z; Gillespie JR; Buckner FS; Verlinde CL; Fan E; Hol WG
    Acta Crystallogr D Biol Crystallogr; 2015 Aug; 71(Pt 8):1684-98. PubMed ID: 26249349
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fragment-based screening in tandem with phenotypic screening provides novel antiparasitic hits.
    Blaazer AR; Orrling KM; Shanmugham A; Jansen C; Maes L; Edink E; Sterk GJ; Siderius M; England P; Bailey D; de Esch IJ; Leurs R
    J Biomol Screen; 2015 Jan; 20(1):131-40. PubMed ID: 25231971
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Anilinoquinoline based inhibitors of trypanosomatid proliferation.
    Ferrins L; Sharma A; Thomas SM; Mehta N; Erath J; Tanghe S; Leed SE; Rodriguez A; Mensa-Wilmot K; Sciotti RJ; Gillingwater K; Pollastri MP
    PLoS Negl Trop Dis; 2018 Nov; 12(11):e0006834. PubMed ID: 30475800
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Oligopeptidase B, a missing enzyme in mammals and a potential drug target for trypanosomatid diseases.
    Motta FN; Azevedo CDS; Neves BP; Araújo CN; Grellier P; Santana JM; Bastos IMD
    Biochimie; 2019 Dec; 167():207-216. PubMed ID: 31628976
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Squalene synthase as a target for Chagas disease therapeutics.
    Shang N; Li Q; Ko TP; Chan HC; Li J; Zheng Y; Huang CH; Ren F; Chen CC; Zhu Z; Galizzi M; Li ZH; Rodrigues-Poveda CA; Gonzalez-Pacanowska D; Veiga-Santos P; de Carvalho TM; de Souza W; Urbina JA; Wang AH; Docampo R; Li K; Liu YL; Oldfield E; Guo RT
    PLoS Pathog; 2014 May; 10(5):e1004114. PubMed ID: 24789335
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, Synthesis and Antiparasitic Evaluation of Click Phospholipids.
    Magoulas GE; Afroudakis P; Georgikopoulou K; Roussaki M; Borsari C; Fotopoulou T; Santarem N; Barrias E; Tejera Nevado P; Hachenberg J; Bifeld E; Ellinger B; Kuzikov M; Fragiadaki I; Scoulica E; Clos J; Gul S; Costi MP; de Souza W; Prousis KC; Cordeiro da Silva A; Calogeropoulou T
    Molecules; 2021 Jul; 26(14):. PubMed ID: 34299479
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Highly improved antiparasitic activity after introduction of an N-benzylimidazole moiety on protein farnesyltransferase inhibitors.
    Bosc D; Mouray E; Cojean S; Franco CH; Loiseau PM; Freitas-Junior LH; Moraes CB; Grellier P; Dubois J
    Eur J Med Chem; 2016 Feb; 109():173-86. PubMed ID: 26774924
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NMR structure of the calflagin Tb24 flagellar calcium binding protein of Trypanosoma brucei.
    Xu X; Olson CL; Engman DM; Ames JB
    Protein Sci; 2012 Dec; 21(12):1942-7. PubMed ID: 23011904
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.