BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

806 related articles for article (PubMed ID: 26908642)

  • 1. Statins inhibit blastocyst formation by preventing geranylgeranylation.
    Alarcon VB; Marikawa Y
    Mol Hum Reprod; 2016 May; 22(5):350-63. PubMed ID: 26908642
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RHOA activity in expanding blastocysts is essential to regulate HIPPO-YAP signaling and to maintain the trophectoderm-specific gene expression program in a ROCK/actin filament-independent manner.
    Marikawa Y; Alarcon VB
    Mol Hum Reprod; 2019 Feb; 25(2):43-60. PubMed ID: 30395288
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Blocking protein geranylgeranylation is essential for lovastatin-induced apoptosis of human acute myeloid leukemia cells.
    Xia Z; Tan MM; Wong WW; Dimitroulakos J; Minden MD; Penn LZ
    Leukemia; 2001 Sep; 15(9):1398-407. PubMed ID: 11516100
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Isoprenoids responsible for protein prenylation modulate the biological effects of statins on pancreatic cancer cells.
    Gbelcová H; Rimpelová S; Knejzlík Z; Šáchová J; Kolář M; Strnad H; Repiská V; D'Acunto WC; Ruml T; Vítek L
    Lipids Health Dis; 2017 Dec; 16(1):250. PubMed ID: 29262834
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of endoplasmic reticulum stress and trophectoderm lineage specification by the mevalonate pathway in the mouse preimplantation embryo.
    Marikawa Y; Menor M; Deng Y; Alarcon VB
    Mol Hum Reprod; 2021 Mar; 27(4):. PubMed ID: 33677573
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Geranylgeranyl-pyrophosphate, an isoprenoid of mevalonate cascade, is a critical compound for rat primary cultured cortical neurons to protect the cell death induced by 3-hydroxy-3-methylglutaryl-CoA reductase inhibition.
    Tanaka T; Tatsuno I; Uchida D; Moroo I; Morio H; Nakamura S; Noguchi Y; Yasuda T; Kitagawa M; Saito Y; Hirai A
    J Neurosci; 2000 Apr; 20(8):2852-9. PubMed ID: 10751437
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Simvastatin suppresses self-renewal of mouse embryonic stem cells by inhibiting RhoA geranylgeranylation.
    Lee MH; Cho YS; Han YM
    Stem Cells; 2007 Jul; 25(7):1654-63. PubMed ID: 17464088
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rho-dependent inhibition of the induction of connective tissue growth factor (CTGF) by HMG CoA reductase inhibitors (statins).
    Eberlein M; Heusinger-Ribeiro J; Goppelt-Struebe M
    Br J Pharmacol; 2001 Aug; 133(7):1172-80. PubMed ID: 11487529
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of farnesyl pyrophosphate accumulation on calvarial osteoblast differentiation.
    Weivoda MM; Hohl RJ
    Endocrinology; 2011 Aug; 152(8):3113-22. PubMed ID: 21586555
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase.
    Laufs U; Liao JK
    J Biol Chem; 1998 Sep; 273(37):24266-71. PubMed ID: 9727051
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 3-Hydroxy-3-methylglutaryl coenzyme a reductase and isoprenylation inhibitors induce apoptosis of vascular smooth muscle cells in culture.
    Guijarro C; Blanco-Colio LM; Ortego M; Alonso C; Ortiz A; Plaza JJ; Díaz C; Hernández G; Egido J
    Circ Res; 1998 Sep; 83(5):490-500. PubMed ID: 9734471
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of geranylgeranylation mediates the effects of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors on microglia.
    Bi X; Baudry M; Liu J; Yao Y; Fu L; Brucher F; Lynch G
    J Biol Chem; 2004 Nov; 279(46):48238-45. PubMed ID: 15364922
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux.
    Argmann CA; Edwards JY; Sawyez CG; O'Neil CH; Hegele RA; Pickering JG; Huff MW
    J Biol Chem; 2005 Jun; 280(23):22212-21. PubMed ID: 15817453
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HMG CoA reductase inhibitor-induced myotoxicity: pravastatin and lovastatin inhibit the geranylgeranylation of low-molecular-weight proteins in neonatal rat muscle cell culture.
    Flint OP; Masters BA; Gregg RE; Durham SK
    Toxicol Appl Pharmacol; 1997 Jul; 145(1):99-110. PubMed ID: 9221829
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modulation of COX-2 expression by statins in human aortic smooth muscle cells. Involvement of geranylgeranylated proteins.
    Degraeve F; Bolla M; Blaie S; Créminon C; Quéré I; Boquet P; Lévy-Toledano S; Bertoglio J; Habib A
    J Biol Chem; 2001 Dec; 276(50):46849-55. PubMed ID: 11591701
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase.
    Kato S; Smalley S; Sadarangani A; Chen-Lin K; Oliva B; Brañes J; Carvajal J; Gejman R; Owen GI; Cuello M
    J Cell Mol Med; 2010 May; 14(5):1180-93. PubMed ID: 19432822
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Metabolic control of YAP and TAZ by the mevalonate pathway.
    Sorrentino G; Ruggeri N; Specchia V; Cordenonsi M; Mano M; Dupont S; Manfrin A; Ingallina E; Sommaggio R; Piazza S; Rosato A; Piccolo S; Del Sal G
    Nat Cell Biol; 2014 Apr; 16(4):357-66. PubMed ID: 24658687
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Geranylgeranylpyrophosphate, a metabolite of mevalonate, regulates the cell cycle progression and DNA synthesis in human lymphocytes.
    Tatsuno I; Tanaka T; Oeda T; Yasuda T; Kitagawa M; Saito Y; Hirai A
    Biochem Biophys Res Commun; 1997 Dec; 241(2):376-82. PubMed ID: 9425279
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Simvastatin suppresses leptin expression in 3T3-L1 adipocytes via activation of the cyclic AMP-PKA pathway induced by inhibition of protein prenylation.
    Maeda T; Horiuchi N
    J Biochem; 2009 Jun; 145(6):771-81. PubMed ID: 19254925
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mevalonate Cascade and its Regulation in Cholesterol Metabolism in Different Tissues in Health and Disease.
    Hashemi M; Hoshyar R; Ande SR; Chen QM; Solomon C; Zuse A; Naderi M
    Curr Mol Pharmacol; 2017; 10(1):13-26. PubMed ID: 26758949
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 41.