444 related articles for article (PubMed ID: 26910619)
1. Disruption of BSEP Function in HepaRG Cells Alters Bile Acid Disposition and Is a Susceptive Factor to Drug-Induced Cholestatic Injury.
Qiu X; Zhang Y; Liu T; Shen H; Xiao Y; Bourner MJ; Pratt JR; Thompson DC; Marathe P; Humphreys WG; Lai Y
Mol Pharm; 2016 Apr; 13(4):1206-16. PubMed ID: 26910619
[TBL] [Abstract][Full Text] [Related]
2. Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs.
Notenboom S; Weigand KM; Proost JH; van Lipzig MMH; van de Steeg E; van den Broek PHH; Greupink R; Russel FGM; Groothuis GMM
Eur J Pharm Sci; 2018 Mar; 115():175-184. PubMed ID: 29309877
[TBL] [Abstract][Full Text] [Related]
3. Drug-induced perturbations of the bile acid pool, cholestasis, and hepatotoxicity: mechanistic considerations beyond the direct inhibition of the bile salt export pump.
Rodrigues AD; Lai Y; Cvijic ME; Elkin LL; Zvyaga T; Soars MG
Drug Metab Dispos; 2014 Apr; 42(4):566-74. PubMed ID: 24115749
[TBL] [Abstract][Full Text] [Related]
4. Metabolic preconditioning protects BSEP/ABCB11
Fuchs CD; Paumgartner G; Wahlström A; Schwabl P; Reiberger T; Leditznig N; Stojakovic T; Rohr-Udilova N; Chiba P; Marschall HU; Trauner M
J Hepatol; 2017 Jan; 66(1):95-101. PubMed ID: 27593105
[TBL] [Abstract][Full Text] [Related]
5. A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Morgan RE; van Staden CJ; Chen Y; Kalyanaraman N; Kalanzi J; Dunn RT; Afshari CA; Hamadeh HK
Toxicol Sci; 2013 Nov; 136(1):216-41. PubMed ID: 23956101
[TBL] [Abstract][Full Text] [Related]
6. Biliary excretion of pravastatin and taurocholate in rats with bile salt export pump (Bsep) impairment.
Cheng Y; Freeden C; Zhang Y; Abraham P; Shen H; Wescott D; Humphreys WG; Gan J; Lai Y
Biopharm Drug Dispos; 2016 Jul; 37(5):276-86. PubMed ID: 27059119
[TBL] [Abstract][Full Text] [Related]
7. In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Dawson S; Stahl S; Paul N; Barber J; Kenna JG
Drug Metab Dispos; 2012 Jan; 40(1):130-8. PubMed ID: 21965623
[TBL] [Abstract][Full Text] [Related]
8. Bile Salt Homeostasis in Normal and Bsep Gene Knockout Rats with Single and Repeated Doses of Troglitazone.
Cheng Y; Chen S; Freeden C; Chen W; Zhang Y; Abraham P; Nelson DM; Humphreys WG; Gan J; Lai Y
J Pharmacol Exp Ther; 2017 Sep; 362(3):385-394. PubMed ID: 28645914
[TBL] [Abstract][Full Text] [Related]
9. Risk factors for development of cholestatic drug-induced liver injury: inhibition of hepatic basolateral bile acid transporters multidrug resistance-associated proteins 3 and 4.
Köck K; Ferslew BC; Netterberg I; Yang K; Urban TJ; Swaan PW; Stewart PW; Brouwer KL
Drug Metab Dispos; 2014 Apr; 42(4):665-74. PubMed ID: 24154606
[TBL] [Abstract][Full Text] [Related]
10. Basal efflux of bile acids contributes to drug-induced bile acid-dependent hepatocyte toxicity in rat sandwich-cultured hepatocytes.
Susukida T; Sekine S; Ogimura E; Aoki S; Oizumi K; Horie T; Ito K
Toxicol In Vitro; 2015 Oct; 29(7):1454-63. PubMed ID: 26055650
[TBL] [Abstract][Full Text] [Related]
11. The inhibition of hepatic bile acids transporters Ntcp and Bsep is involved in the pathogenesis of isoniazid/rifampicin-induced hepatotoxicity.
Guo YX; Xu XF; Zhang QZ; Li C; Deng Y; Jiang P; He LY; Peng WX
Toxicol Mech Methods; 2015; 25(5):382-7. PubMed ID: 25886055
[TBL] [Abstract][Full Text] [Related]
12. Effect of a Common Genetic Variant (p.V444A) in the Bile Salt Export Pump on the Inhibition of Bile Acid Transport by Cholestatic Medications.
Ali I; Khalid S; Stieger B; Brouwer KLR
Mol Pharm; 2019 Mar; 16(3):1406-1411. PubMed ID: 30608704
[TBL] [Abstract][Full Text] [Related]
13. Establishment of a Drug-Induced, Bile Acid-Dependent Hepatotoxicity Model Using HepaRG Cells.
Susukida T; Sekine S; Nozaki M; Tokizono M; Oizumi K; Horie T; Ito K
J Pharm Sci; 2016 Apr; 105(4):1550-60. PubMed ID: 26952880
[TBL] [Abstract][Full Text] [Related]
14. Bile salt export pump inhibitors are associated with bile acid-dependent drug-induced toxicity in sandwich-cultured hepatocytes.
Ogimura E; Sekine S; Horie T
Biochem Biophys Res Commun; 2011 Dec; 416(3-4):313-7. PubMed ID: 22108051
[TBL] [Abstract][Full Text] [Related]
15. Toward predicting drug-induced liver injury: parallel computational approaches to identify multidrug resistance protein 4 and bile salt export pump inhibitors.
Welch MA; Köck K; Urban TJ; Brouwer KL; Swaan PW
Drug Metab Dispos; 2015 May; 43(5):725-34. PubMed ID: 25735837
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of bile salt transport by drugs associated with liver injury in primary hepatocytes from human, monkey, dog, rat, and mouse.
Zhang J; He K; Cai L; Chen YC; Yang Y; Shi Q; Woolf TF; Ge W; Guo L; Borlak J; Tong W
Chem Biol Interact; 2016 Aug; 255():45-54. PubMed ID: 27000539
[TBL] [Abstract][Full Text] [Related]
17. The role of bile salt export pump gene repression in drug-induced cholestatic liver toxicity.
Garzel B; Yang H; Zhang L; Huang SM; Polli JE; Wang H
Drug Metab Dispos; 2014 Mar; 42(3):318-22. PubMed ID: 24335466
[TBL] [Abstract][Full Text] [Related]
18. Cholestatic potential of troglitazone as a possible factor contributing to troglitazone-induced hepatotoxicity: in vivo and in vitro interaction at the canalicular bile salt export pump (Bsep) in the rat.
Funk C; Ponelle C; Scheuermann G; Pantze M
Mol Pharmacol; 2001 Mar; 59(3):627-35. PubMed ID: 11179459
[TBL] [Abstract][Full Text] [Related]
19. Oxidative stress plays a major role in chlorpromazine-induced cholestasis in human HepaRG cells.
Anthérieu S; Bachour-El Azzi P; Dumont J; Abdel-Razzak Z; Guguen-Guillouzo C; Fromenty B; Robin MA; Guillouzo A
Hepatology; 2013 Apr; 57(4):1518-29. PubMed ID: 23175273
[TBL] [Abstract][Full Text] [Related]
20. The role of the sodium-taurocholate cotransporting polypeptide (NTCP) and of the bile salt export pump (BSEP) in physiology and pathophysiology of bile formation.
Stieger B
Handb Exp Pharmacol; 2011; (201):205-59. PubMed ID: 21103971
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]