505 related articles for article (PubMed ID: 26910900)
1. Retigabine, a Kv7.2/Kv7.3-Channel Opener, Attenuates Drug-Induced Seizures in Knock-In Mice Harboring Kcnq2 Mutations.
Ihara Y; Tomonoh Y; Deshimaru M; Zhang B; Uchida T; Ishii A; Hirose S
PLoS One; 2016; 11(2):e0150095. PubMed ID: 26910900
[TBL] [Abstract][Full Text] [Related]
2. Sequence determinants of subtype-specific actions of KCNQ channel openers.
Wang AW; Yang R; Kurata HT
J Physiol; 2017 Feb; 595(3):663-676. PubMed ID: 27506413
[TBL] [Abstract][Full Text] [Related]
3. The Sensorless Pore Module of Voltage-gated K+ Channel Family 7 Embodies the Target Site for the Anticonvulsant Retigabine.
Syeda R; Santos JS; Montal M
J Biol Chem; 2016 Feb; 291(6):2931-7. PubMed ID: 26627826
[TBL] [Abstract][Full Text] [Related]
4. Removal of KCNQ2 from parvalbumin-expressing interneurons improves anti-seizure efficacy of retigabine.
Jing J; Dunbar C; Sonesra A; Chavez A; Park S; Yang R; Soh H; Lee M; Tzingounis AV; Cooper EC; Jiang X; Maheshwari A
Exp Neurol; 2022 Sep; 355():114141. PubMed ID: 35691372
[TBL] [Abstract][Full Text] [Related]
5. Functional and behavioral signatures of Kv7 activator drug subtypes.
Kanyo R; Wang CK; Locskai LF; Li J; Allison WT; Kurata HT
Epilepsia; 2020 Aug; 61(8):1678-1690. PubMed ID: 32652600
[TBL] [Abstract][Full Text] [Related]
6. Mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions show seizures and neuronal plasticity without synaptic reorganization.
Singh NA; Otto JF; Dahle EJ; Pappas C; Leslie JD; Vilaythong A; Noebels JL; White HS; Wilcox KS; Leppert MF
J Physiol; 2008 Jul; 586(14):3405-23. PubMed ID: 18483067
[TBL] [Abstract][Full Text] [Related]
7. Functional characterization and in vitro pharmacological rescue of KCNQ2 pore mutations associated with epileptic encephalopathy.
Yang GM; Tian FY; Shen YW; Yang CY; Yuan H; Li P; Gao ZB
Acta Pharmacol Sin; 2023 Aug; 44(8):1589-1599. PubMed ID: 36932231
[TBL] [Abstract][Full Text] [Related]
8. Personalized treatment with retigabine for pharmacoresistant epilepsy arising from a pathogenic variant in the KCNQ2 selectivity filter.
Nissenkorn A; Kornilov P; Peretz A; Blumkin L; Heimer G; Ben-Zeev B; Attali B
Epileptic Disord; 2021 Oct; 23(5):695-705. PubMed ID: 34519644
[TBL] [Abstract][Full Text] [Related]
9. Molecular Mechanisms and Structural Basis of Retigabine Analogues in Regulating KCNQ2 Channel.
Shi S; Li J; Sun F; Chen Y; Pang C; Geng Y; Qi J; Guo S; Wang X; Zhang H; Zhan Y; An H
J Membr Biol; 2020 Apr; 253(2):167-181. PubMed ID: 32170353
[TBL] [Abstract][Full Text] [Related]
10. Effects of KCNQ2 gene truncation on M-type Kv7 potassium currents.
Robbins J; Passmore GM; Abogadie FC; Reilly JM; Brown DA
PLoS One; 2013; 8(8):e71809. PubMed ID: 23977150
[TBL] [Abstract][Full Text] [Related]
11. The mechanism of action of retigabine (ezogabine), a first-in-class K+ channel opener for the treatment of epilepsy.
Gunthorpe MJ; Large CH; Sankar R
Epilepsia; 2012 Mar; 53(3):412-24. PubMed ID: 22220513
[TBL] [Abstract][Full Text] [Related]
12. Kcnq2/Kv7.2 controls the threshold and bi-hemispheric symmetry of cortical spreading depolarization.
Aiba I; Noebels JL
Brain; 2021 Oct; 144(9):2863-2878. PubMed ID: 33768249
[TBL] [Abstract][Full Text] [Related]
13. KCNQ2/3 openers show differential selectivity and site of action across multiple KCNQ channels.
Zhang D; Thimmapaya R; Zhang XF; Anderson DJ; Baranowski JL; Scanio M; Perez-Medrano A; Peddi S; Wang Z; Patel JR; DeGoey DA; Gopalakrishnan M; Honore P; Yao BB; Surowy CS
J Neurosci Methods; 2011 Aug; 200(1):54-62. PubMed ID: 21723881
[TBL] [Abstract][Full Text] [Related]
14. Kv7.3 Compound Heterozygous Variants in Early Onset Encephalopathy Reveal Additive Contribution of C-Terminal Residues to PIP
Ambrosino P; Freri E; Castellotti B; Soldovieri MV; Mosca I; Manocchio L; Gellera C; Canafoglia L; Franceschetti S; Salis B; Iraci N; Miceli F; Ragona F; Granata T; DiFrancesco JC; Taglialatela M
Mol Neurobiol; 2018 Aug; 55(8):7009-7024. PubMed ID: 29383681
[TBL] [Abstract][Full Text] [Related]
15. Retigabine holds KV7 channels open and stabilizes the resting potential.
Corbin-Leftwich A; Mossadeq SM; Ha J; Ruchala I; Le AH; Villalba-Galea CA
J Gen Physiol; 2016 Mar; 147(3):229-41. PubMed ID: 26880756
[TBL] [Abstract][Full Text] [Related]
16. Electroconvulsive seizure thresholds and kindling acquisition rates are altered in mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions.
Otto JF; Singh NA; Dahle EJ; Leppert MF; Pappas CM; Pruess TH; Wilcox KS; White HS
Epilepsia; 2009 Jul; 50(7):1752-9. PubMed ID: 19453707
[TBL] [Abstract][Full Text] [Related]
17. The KCNQ2/3 selective channel opener ICA-27243 binds to a novel voltage-sensor domain site.
Padilla K; Wickenden AD; Gerlach AC; McCormack K
Neurosci Lett; 2009 Nov; 465(2):138-42. PubMed ID: 19733209
[TBL] [Abstract][Full Text] [Related]
18. Genotype-phenotype correlations in neonatal epilepsies caused by mutations in the voltage sensor of K(v)7.2 potassium channel subunits.
Miceli F; Soldovieri MV; Ambrosino P; Barrese V; Migliore M; Cilio MR; Taglialatela M
Proc Natl Acad Sci U S A; 2013 Mar; 110(11):4386-91. PubMed ID: 23440208
[TBL] [Abstract][Full Text] [Related]
19. The novel dual-mechanism Kv7 potassium channel/TSPO receptor activator GRT-X is more effective than the Kv7 channel opener retigabine in the 6-Hz refractory seizure mouse model.
Bloms-Funke P; Bankstahl M; Bankstahl J; Kneip C; Schröder W; Löscher W
Neuropharmacology; 2022 Feb; 203():108884. PubMed ID: 34785163
[TBL] [Abstract][Full Text] [Related]
20. The SUMO-specific protease SENP2 plays an essential role in the regulation of Kv7.2 and Kv7.3 potassium channels.
Chen X; Zhang Y; Ren X; Su Q; Liu Y; Dang X; Qin Y; Yang X; Xing Z; Shen Y; Wang Y; Bai Z; Yeh ETH; Wu H; Qi Y
J Biol Chem; 2021 Oct; 297(4):101183. PubMed ID: 34509475
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
