BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

323 related articles for article (PubMed ID: 26911561)

  • 1. QSAR study on the antimalarial activity of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitors.
    Hou X; Chen X; Zhang M; Yan A
    SAR QSAR Environ Res; 2016; 27(2):101-24. PubMed ID: 26911561
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Understanding the structural requirements in diverse scaffolds for the inhibition of P. falciparum dihydroorotate dehydrogenase (PfDHODH) using 2D-QSAR, 3D-pharmacophore and structure-based energy- optimized pharmacophore models.
    Aher RB; Roy K
    Comb Chem High Throughput Screen; 2015; 18(2):217-26. PubMed ID: 25543684
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evaluation of 7-arylaminopyrazolo[1,5-a]pyrimidines as anti-Plasmodium falciparum, antimalarial, and Pf-dihydroorotate dehydrogenase inhibitors.
    Azeredo LFSP; Coutinho JP; Jabor VAP; Feliciano PR; Nonato MC; Kaiser CR; Menezes CMS; Hammes ASO; Caffarena ER; Hoelz LVB; de Souza NB; Pereira GAN; Cerávolo IP; Krettli AU; Boechat N
    Eur J Med Chem; 2017 Jan; 126():72-83. PubMed ID: 27744189
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparative study between 3D-QSAR and Docking-Based Pharmacophore models for potent Plasomodium falciparum dihydroorotate dehydrogenase inhibitors.
    Tseng TS; Lee YC; Hsiao NW; Liu YR; Tsai KC
    Bioorg Med Chem Lett; 2016 Jan; 26(2):265-271. PubMed ID: 26707392
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Plasmodium falciparum dihydroorotate dehydrogenase: a drug target against malaria.
    Hoelz LV; Calil FA; Nonato MC; Pinheiro LC; Boechat N
    Future Med Chem; 2018 Aug; 10(15):1853-1874. PubMed ID: 30019917
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of 3,4-Dihydro-2
    Hartuti ED; Sakura T; Tagod MSO; Yoshida E; Wang X; Mochizuki K; Acharjee R; Matsuo Y; Tokumasu F; Mori M; Waluyo D; Shiomi K; Nozaki T; Hamano S; Shiba T; Kita K; Inaoka DK
    Int J Mol Sci; 2021 Jul; 22(13):. PubMed ID: 34281290
    [No Abstract]   [Full Text] [Related]  

  • 7. Identification of New Human Malaria Parasite Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors by Pharmacophore and Structure-Based Virtual Screening.
    Pavadai E; El Mazouni F; Wittlin S; de Kock C; Phillips MA; Chibale K
    J Chem Inf Model; 2016 Mar; 56(3):548-62. PubMed ID: 26915022
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of novel PfDHODH inhibitors as antimalarial agents via pharmacophore-based virtual screening followed by molecular docking and in vivo antimalarial activity.
    Vyas VK; Qureshi G; Ghate M; Patel H; Dalai S
    SAR QSAR Environ Res; 2016 Jun; 27(6):427-40. PubMed ID: 27310104
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design and tests of prospective property predictions for novel antimalarial 2-aminopropylaminoquinolones.
    Clark RD; Morris DN; Chinigo G; Lawless MS; Prudhomme J; Le Roch KG; Lafuente MJ; Ferrer S; Gamo FJ; Gadwood R; Woltosz WS
    J Comput Aided Mol Des; 2020 Nov; 34(11):1117-1132. PubMed ID: 32833084
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recent advances on patents of
    Gehlot P; Vyas VK
    Expert Opin Ther Pat; 2023; 33(9):579-596. PubMed ID: 37942637
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chemometric modeling, docking and in silico design of triazolopyrimidine-based dihydroorotate dehydrogenase inhibitors as antimalarials.
    Ojha PK; Roy K
    Eur J Med Chem; 2010 Oct; 45(10):4645-56. PubMed ID: 20708304
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, Design, and Structure⁻Activity Relationship of the Pyrimidone Derivatives as Novel Selective Inhibitors of
    Xu L; Li W; Diao Y; Sun H; Li H; Zhu L; Zhou H; Zhao Z
    Molecules; 2018 May; 23(6):. PubMed ID: 29794978
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In silico identification of novel inhibitors against Plasmodium falciparum dihydroorate dehydrogenase.
    Wadood A; Ulhaq ZU
    J Mol Graph Model; 2013 Mar; 40():40-7. PubMed ID: 23353582
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel selective and potent inhibitors of malaria parasite dihydroorotate dehydrogenase: discovery and optimization of dihydrothiophenone derivatives.
    Xu M; Zhu J; Diao Y; Zhou H; Ren X; Sun D; Huang J; Han D; Zhao Z; Zhu L; Xu Y; Li H
    J Med Chem; 2013 Oct; 56(20):7911-24. PubMed ID: 24073986
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Triazolopyrimidine-based dihydroorotate dehydrogenase inhibitors with potent and selective activity against the malaria parasite Plasmodium falciparum.
    Phillips MA; Gujjar R; Malmquist NA; White J; El Mazouni F; Baldwin J; Rathod PK
    J Med Chem; 2008 Jun; 51(12):3649-53. PubMed ID: 18522386
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors.
    Silveira FF; de Souza JO; Hoelz LVB; Campos VR; Jabor VAP; Aguiar ACC; Nonato MC; Albuquerque MG; Guido RVC; Boechat N; Pinheiro LCS
    Eur J Med Chem; 2021 Jan; 209():112941. PubMed ID: 33158577
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In-Silico molecular docking and simulation studies on novel chalcone and flavone hybrid derivatives with 1, 2, 3-triazole linkage as vital inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase.
    Thillainayagam M; Malathi K; Ramaiah S
    J Biomol Struct Dyn; 2018 Nov; 36(15):3993-4009. PubMed ID: 29132266
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Coptisine, a natural alkaloid from Coptidis Rhizoma, inhibits plasmodium falciparum dihydroorotate dehydrogenase.
    Lang L; Hu Q; Wang J; Liu Z; Huang J; Lu W; Huang Y
    Chem Biol Drug Des; 2018 Jul; 92(1):1324-1332. PubMed ID: 29582555
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lead optimization of aryl and aralkyl amine-based triazolopyrimidine inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with antimalarial activity in mice.
    Gujjar R; El Mazouni F; White KL; White J; Creason S; Shackleford DM; Deng X; Charman WN; Bathurst I; Burrows J; Floyd DM; Matthews D; Buckner FS; Charman SA; Phillips MA; Rathod PK
    J Med Chem; 2011 Jun; 54(11):3935-49. PubMed ID: 21517059
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In vitro resistance selections for Plasmodium falciparum dihydroorotate dehydrogenase inhibitors give mutants with multiple point mutations in the drug-binding site and altered growth.
    Ross LS; Gamo FJ; Lafuente-Monasterio MJ; Singh OM; Rowland P; Wiegand RC; Wirth DF
    J Biol Chem; 2014 Jun; 289(26):17980-95. PubMed ID: 24782313
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.