These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 26918322)

  • 1. Development and Characterization of Novel and Selective Inhibitors of Cytochrome P450 CYP26A1, the Human Liver Retinoic Acid Hydroxylase.
    Diaz P; Huang W; Keyari CM; Buttrick B; Price L; Guilloteau N; Tripathy S; Sperandio VG; Fronczek FR; Astruc-Diaz F; Isoherranen N
    J Med Chem; 2016 Mar; 59(6):2579-95. PubMed ID: 26918322
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Substrate specificity and ligand interactions of CYP26A1, the human liver retinoic acid hydroxylase.
    Thatcher JE; Buttrick B; Shaffer SA; Shimshoni JA; Goodlett DR; Nelson WL; Isoherranen N
    Mol Pharmacol; 2011 Aug; 80(2):228-39. PubMed ID: 21521770
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of the
    Stevison F; Hogarth C; Tripathy S; Kent T; Isoherranen N
    Drug Metab Dispos; 2017 Jul; 45(7):846-854. PubMed ID: 28446509
    [No Abstract]   [Full Text] [Related]  

  • 4. Comparison of the function and expression of CYP26A1 and CYP26B1, the two retinoic acid hydroxylases.
    Topletz AR; Thatcher JE; Zelter A; Lutz JD; Tay S; Nelson WL; Isoherranen N
    Biochem Pharmacol; 2012 Jan; 83(1):149-63. PubMed ID: 22020119
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A comparison of the roles of peroxisome proliferator-activated receptor and retinoic acid receptor on CYP26 regulation.
    Tay S; Dickmann L; Dixit V; Isoherranen N
    Mol Pharmacol; 2010 Feb; 77(2):218-27. PubMed ID: 19884280
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lipopolysaccharide opposes the induction of CYP26A1 and CYP26B1 gene expression by retinoic acid in the rat liver in vivo.
    Zolfaghari R; Cifelli CJ; Lieu SO; Chen Q; Li NQ; Ross AC
    Am J Physiol Gastrointest Liver Physiol; 2007 Apr; 292(4):G1029-36. PubMed ID: 17185629
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of Tazarotenic Acid as the First Xenobiotic Substrate of Human Retinoic Acid Hydroxylase CYP26A1 and CYP26B1.
    Foti RS; Isoherranen N; Zelter A; Dickmann LJ; Buttrick BR; Diaz P; Douguet D
    J Pharmacol Exp Ther; 2016 May; 357(2):281-92. PubMed ID: 26937021
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of a highly specific retinoic acid-4-hydroxylase (CYP26A1) enzyme and all-trans-retinoic acid metabolism in human intestinal, liver, endothelial, and acute promyelocytic leukemia cells.
    Ozpolat B; Mehta K; Lopez-Berestein G
    Leuk Lymphoma; 2005 Oct; 46(10):1497-506. PubMed ID: 16194896
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, and biological evaluation of amide imidazole derivatives as novel metabolic enzyme CYP26A1 inhibitors.
    Sun B; Liu K; Han J; Zhao LY; Su X; Lin B; Zhao DM; Cheng MS
    Bioorg Med Chem; 2015 Oct; 23(20):6763-73. PubMed ID: 26365710
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel human cytochrome P450, CYP26C1, involved in metabolism of 9-cis and all-trans isomers of retinoic acid.
    Taimi M; Helvig C; Wisniewski J; Ramshaw H; White J; Amad M; Korczak B; Petkovich M
    J Biol Chem; 2004 Jan; 279(1):77-85. PubMed ID: 14532297
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of CYP26A1 by metabolites of retinoic acid: evidence that CYP26A1 is an important enzyme in the elimination of active retinoids.
    Topletz AR; Tripathy S; Foti RS; Shimshoni JA; Nelson WL; Isoherranen N
    Mol Pharmacol; 2015; 87(3):430-41. PubMed ID: 25492813
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular recognition of CYP26A1 binding pockets and structure-activity relationship studies for design of potent and selective retinoic acid metabolism blocking agents.
    Sun B; Song S; Hao CZ; Huang WX; Liu CC; Xie HL; Lin B; Cheng MS; Zhao DM
    J Mol Graph Model; 2015 Mar; 56():10-9. PubMed ID: 25541526
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel azolyl-(phenylmethyl)]aryl/heteroarylamines: potent CYP26 inhibitors and enhancers of all-trans retinoic acid activity in neuroblastoma cells.
    Gomaa MS; Armstrong JL; Bobillon B; Veal GJ; Brancale A; Redfern CP; Simons C
    Bioorg Med Chem; 2008 Sep; 16(17):8301-13. PubMed ID: 18722776
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of NADPH-cytochrome P450 reductase on all-trans-retinoic acid efficacy and cytochrome P450 26A1 expression in human myeloid leukaemia HL-60 cells.
    Hu L; Lv JF; Zhuo W; Zhang CM; Zhou HH; Fan L
    J Pharm Pharmacol; 2016 Sep; 68(9):1193-202. PubMed ID: 27366899
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CRABPs Alter
    Yabut KCB; Isoherranen N
    Nutrients; 2022 Apr; 14(9):. PubMed ID: 35565751
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cytochrome p450 retinoic acid 4-hydroxylase inhibitors: potential agents for cancer therapy.
    Njar VC
    Mini Rev Med Chem; 2002 Jun; 2(3):261-9. PubMed ID: 12370067
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Comparison of the ligand binding site of CYP2C8 with CYP26A1 and CYP26B1: a structural basis for the identification of new inhibitors of the retinoic acid hydroxylases.
    Foti RS; Diaz P; Douguet D
    J Enzyme Inhib Med Chem; 2016; 31(sup2):148-161. PubMed ID: 27424662
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development and validation of CYP26A1 inhibition assay for high-throughput screening.
    Sakamuru S; Ma D; Pierro JD; Baker NC; Kleinstreuer N; Cali JJ; Knudsen TB; Xia M
    Biotechnol J; 2024 Jun; 19(6):e2300659. PubMed ID: 38863121
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Small molecule inhibitors of retinoic acid 4-hydroxylase (CYP26): synthesis and biological evaluation of imidazole methyl 3-(4-(aryl-2-ylamino)phenyl)propanoates.
    Gomaa MS; Bridgens CE; Aboraia AS; Veal GJ; Redfern CP; Brancale A; Armstrong JL; Simons C
    J Med Chem; 2011 Apr; 54(8):2778-91. PubMed ID: 21428449
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CYP26B1 plays a major role in the regulation of all-trans-retinoic acid metabolism and signaling in human aortic smooth muscle cells.
    Ocaya PA; Elmabsout AA; Olofsson PS; Törmä H; Gidlöf AC; Sirsjö A
    J Vasc Res; 2011; 48(1):23-30. PubMed ID: 20606468
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.