BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

280 related articles for article (PubMed ID: 26921248)

  • 1. CHK1 regulates NF-κB signaling upon DNA damage in p53- deficient cells and associated tumor-derived microvesicles.
    Carroll BL; Pulkoski-Gross MJ; Hannun YA; Obeid LM
    Oncotarget; 2016 Apr; 7(14):18159-70. PubMed ID: 26921248
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Selective Chk1 inhibitors differentially sensitize p53-deficient cancer cells to cancer therapeutics.
    Chen Z; Xiao Z; Gu WZ; Xue J; Bui MH; Kovar P; Li G; Wang G; Tao ZF; Tong Y; Lin NH; Sham HL; Wang JY; Sowin TJ; Rosenberg SH; Zhang H
    Int J Cancer; 2006 Dec; 119(12):2784-94. PubMed ID: 17019715
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Simulated Microgravity Promotes Cell Apoptosis Through Suppressing Uev1A/TICAM/TRAF/NF-κB-Regulated Anti-Apoptosis and p53/PCNA- and ATM/ATR-Chk1/2-Controlled DNA-Damage Response Pathways.
    Zhao T; Tang X; Umeshappa CS; Ma H; Gao H; Deng Y; Freywald A; Xiang J
    J Cell Biochem; 2016 Sep; 117(9):2138-48. PubMed ID: 26887372
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Knockdown of Chk1 sensitizes human colon carcinoma HCT116 cells in a p53-dependent manner to lidamycin through abrogation of a G2/M checkpoint and induction of apoptosis.
    Pan Y; Ren KH; He HW; Shao RG
    Cancer Biol Ther; 2009 Aug; 8(16):1559-66. PubMed ID: 19502782
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Profilin potentiates chemotherapeutic agents mediated cell death via suppression of NF-κB and upregulation of p53.
    Zaidi AH; Raviprakash N; Mokhamatam RB; Gupta P; Manna SK
    Apoptosis; 2016 Apr; 21(4):502-13. PubMed ID: 26842845
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nuclear factor-(kappa)B modulates the p53 response in neurons exposed to DNA damage.
    Aleyasin H; Cregan SP; Iyirhiaro G; O'Hare MJ; Callaghan SM; Slack RS; Park DS
    J Neurosci; 2004 Mar; 24(12):2963-73. PubMed ID: 15044535
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1.
    Duan L; Perez RE; Hansen M; Gitelis S; Maki CG
    Cancer Biol Ther; 2014; 15(12):1600-12. PubMed ID: 25482935
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chk1 instability is coupled to mitotic cell death of p53-deficient cells in response to virus-induced DNA damage signaling.
    Jurvansuu J; Fragkos M; Ingemarsdotter C; Beard P
    J Mol Biol; 2007 Sep; 372(2):397-406. PubMed ID: 17663993
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The canonical NF-κB pathway differentially protects normal and human tumor cells from ROS-induced DNA damage.
    Sfikas A; Batsi C; Tselikou E; Vartholomatos G; Monokrousos N; Pappas P; Christoforidis S; Tzavaras T; Kanavaros P; Gorgoulis VG; Marcu KB; Kolettas E
    Cell Signal; 2012 Nov; 24(11):2007-23. PubMed ID: 22750558
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Insight into the role of PIKK family members and NF-кB in DNAdamage-induced senescence and senescence-associated secretory phenotype of colon cancer cells.
    Strzeszewska A; Alster O; Mosieniak G; Ciolko A; Sikora E
    Cell Death Dis; 2018 Jan; 9(2):44. PubMed ID: 29352261
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Co-Inhibition of the DNA Damage Response and CHK1 Enhances Apoptosis of Neuroblastoma Cells.
    Ando K; Nakamura Y; Nagase H; Nakagawara A; Koshinaga T; Wada S; Makishima M
    Int J Mol Sci; 2019 Jul; 20(15):. PubMed ID: 31362335
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional.
    Lossaint G; Besnard E; Fisher D; Piette J; Dulić V
    Oncogene; 2011 Oct; 30(41):4261-74. PubMed ID: 21532626
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.
    Menendez JA; Mehmi I; Atlas E; Colomer R; Lupu R
    Int J Oncol; 2004 Mar; 24(3):591-608. PubMed ID: 14767544
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chk1 and Wee1 control genotoxic-stress induced G2-M arrest in melanoma cells.
    Vera J; Raatz Y; Wolkenhauer O; Kottek T; Bhattacharya A; Simon JC; Kunz M
    Cell Signal; 2015 May; 27(5):951-60. PubMed ID: 25683911
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Temozolomide Induces Senescence and Repression of DNA Repair Pathways in Glioblastoma Cells via Activation of ATR-CHK1, p21, and NF-κB.
    Aasland D; Götzinger L; Hauck L; Berte N; Meyer J; Effenberger M; Schneider S; Reuber EE; Roos WP; Tomicic MT; Kaina B; Christmann M
    Cancer Res; 2019 Jan; 79(1):99-113. PubMed ID: 30361254
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Replication and ribosomal stress induced by targeting pyrimidine synthesis and cellular checkpoints suppress p53-deficient tumors.
    Hubackova S; Davidova E; Boukalova S; Kovarova J; Bajzikova M; Coelho A; Terp MG; Ditzel HJ; Rohlena J; Neuzil J
    Cell Death Dis; 2020 Feb; 11(2):110. PubMed ID: 32034120
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Xanthatin triggers Chk1-mediated DNA damage response and destabilizes Cdc25C via lysosomal degradation in lung cancer cells.
    Tao L; Cao Y; Wei Z; Jia Q; Yu S; Zhong J; Wang A; Woodgett JR; Lu Y
    Toxicol Appl Pharmacol; 2017 Dec; 337():85-94. PubMed ID: 29074359
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of NF-kappaB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor.
    Rocha S; Garrett MD; Campbell KJ; Schumm K; Perkins ND
    EMBO J; 2005 Mar; 24(6):1157-69. PubMed ID: 15775976
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Checkpoint kinase 1 down-regulation by an inducible small interfering RNA expression system sensitized in vivo tumors to treatment with 5-fluorouracil.
    Ganzinelli M; Carrassa L; Crippa F; Tavecchio M; Broggini M; Damia G
    Clin Cancer Res; 2008 Aug; 14(16):5131-41. PubMed ID: 18698031
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The checkpoint 1 kinase inhibitor LY2603618 induces cell cycle arrest, DNA damage response and autophagy in cancer cells.
    Wang FZ; Fei HR; Cui YJ; Sun YK; Li ZM; Wang XY; Yang XY; Zhang JG; Sun BL
    Apoptosis; 2014 Sep; 19(9):1389-98. PubMed ID: 24928205
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.