BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

238 related articles for article (PubMed ID: 26926468)

  • 1. Polypharmacology of Approved Anticancer Drugs.
    Amelio I; Lisitsa A; Knight RA; Melino G; Antonov AV
    Curr Drug Targets; 2017; 18(5):534-543. PubMed ID: 26926468
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Polypharmacology: challenges and opportunities in drug discovery.
    Anighoro A; Bajorath J; Rastelli G
    J Med Chem; 2014 Oct; 57(19):7874-87. PubMed ID: 24946140
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Epigenetic polypharmacology: from combination therapy to multitargeted drugs.
    de Lera AR; Ganesan A
    Clin Epigenetics; 2016; 8():105. PubMed ID: 27752293
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Polypharmacology in Precision Oncology: Current Applications and Future Prospects.
    Antolin AA; Workman P; Mestres J; Al-Lazikani B
    Curr Pharm Des; 2016; 22(46):6935-6945. PubMed ID: 27669965
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Human Kinome Targeted by FDA Approved Multi-Target Drugs and Combination Products: A Comparative Study from the Drug-Target Interaction Network Perspective.
    Li YH; Wang PP; Li XX; Yu CY; Yang H; Zhou J; Xue WW; Tan J; Zhu F
    PLoS One; 2016; 11(11):e0165737. PubMed ID: 27828998
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Network pharmacology: the next paradigm in drug discovery.
    Hopkins AL
    Nat Chem Biol; 2008 Nov; 4(11):682-90. PubMed ID: 18936753
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Histone Deacetylase Inhibitors as Multitarget-Directed Epi-Drugs in Blocking PI3K Oncogenic Signaling: A Polypharmacology Approach.
    Ranganna K; Selvam C; Shivachar A; Yousefipour Z
    Int J Mol Sci; 2020 Nov; 21(21):. PubMed ID: 33147762
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Improvement of conventional anti-cancer drugs as new tools against multidrug resistant tumors.
    Dallavalle S; Dobričić V; Lazzarato L; Gazzano E; Machuqueiro M; Pajeva I; Tsakovska I; Zidar N; Fruttero R
    Drug Resist Updat; 2020 May; 50():100682. PubMed ID: 32087558
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dual Inhibitors of Human DNA Topoisomerase II and Other Cancer-Related Targets.
    Skok Ž; Zidar N; Kikelj D; Ilaš J
    J Med Chem; 2020 Feb; 63(3):884-904. PubMed ID: 31592646
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Epigenetic polypharmacology: A new frontier for epi-drug discovery.
    Tomaselli D; Lucidi A; Rotili D; Mai A
    Med Res Rev; 2020 Jan; 40(1):190-244. PubMed ID: 31218726
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Exploiting polypharmacology for improving therapeutic outcome of kinase inhibitors (KIs): An update of recent medicinal chemistry efforts.
    Ma X; Lv X; Zhang J
    Eur J Med Chem; 2018 Jan; 143():449-463. PubMed ID: 29202407
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In Silico Oncology Drug Repositioning and Polypharmacology.
    Cheng F
    Methods Mol Biol; 2019; 1878():243-261. PubMed ID: 30378081
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Multitarget Drug Discovery and Polypharmacology.
    Bolognesi ML; Cavalli A
    ChemMedChem; 2016 Jun; 11(12):1190-2. PubMed ID: 27061625
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Histone deacetylases as an epigenetic pillar for the development of hybrid inhibitors in cancer.
    Stazi G; Fioravanti R; Mai A; Mattevi A; Valente S
    Curr Opin Chem Biol; 2019 Jun; 50():89-100. PubMed ID: 30986654
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery and Development of Topoisomerase Inhibitors as Anticancer Agents.
    Kathiravan MK; Kale AN; Nilewar S
    Mini Rev Med Chem; 2016; 16(15):1219-1229. PubMed ID: 27549098
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Turning liabilities into opportunities: Off-target based drug repurposing in cancer.
    Palve V; Liao Y; Remsing Rix LL; Rix U
    Semin Cancer Biol; 2021 Jan; 68():209-229. PubMed ID: 32044472
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Multi-Targeting Anticancer Agents: Rational Approaches, Synthetic Routes and Structure Activity Relationship.
    Singh H; Kinarivala N; Sharma S
    Anticancer Agents Med Chem; 2019; 19(7):842-874. PubMed ID: 30657048
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Exploration of the mechanism of traditional Chinese medicine by AI approach using unsupervised machine learning for cellular functional similarity of compounds in heterogeneous networks, XiaoErFuPi granules as an example.
    Guo F; Tang X; Zhang W; Wei J; Tang S; Wu H; Yang H
    Pharmacol Res; 2020 Oct; 160():105077. PubMed ID: 32687952
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of type-specific anticancer histone deacetylase inhibitors: road to success.
    Noureen N; Rashid H; Kalsoom S
    Cancer Chemother Pharmacol; 2010 Sep; 66(4):625-33. PubMed ID: 20401613
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Drugs Polypharmacology by In Silico Methods: New Opportunities in Drug Discovery.
    Lauria A; Bonsignore R; Bartolotta R; Perricone U; Martorana A; Gentile C
    Curr Pharm Des; 2016; 22(21):3073-81. PubMed ID: 26907944
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.