BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

104 related articles for article (PubMed ID: 26927311)

  • 1. Assessing the ligand selectivity of sphingosine kinases using molecular dynamics and MM-PBSA binding free energy calculations.
    Fang L; Wang X; Xi M; Liu T; Yin D
    Mol Biosyst; 2016 Apr; 12(4):1174-82. PubMed ID: 26927311
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In Silico Identification of Novel Orthosteric Inhibitors of Sphingosine Kinase 1 (SK1).
    Bayraktar O; Ozkirimli E; Ulgen KO
    Curr Protein Pept Sci; 2018; 19(5):430-444. PubMed ID: 27829348
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sphingosine Kinases: Emerging Structure-Function Insights.
    Adams DR; Pyne S; Pyne NJ
    Trends Biochem Sci; 2016 May; 41(5):395-409. PubMed ID: 27021309
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Topographical Mapping of Isoform-Selectivity Determinants for J-Channel-Binding Inhibitors of Sphingosine Kinases 1 and 2.
    Adams DR; Tawati S; Berretta G; Rivas PL; Baiget J; Jiang Z; Alsfouk A; Mackay SP; Pyne NJ; Pyne S
    J Med Chem; 2019 Apr; 62(7):3658-3676. PubMed ID: 30889352
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of isoenzyme-selective inhibitors of human sphingosine kinases.
    Gao P; Peterson YK; Smith RA; Smith CD
    PLoS One; 2012; 7(9):e44543. PubMed ID: 22970244
    [TBL] [Abstract][Full Text] [Related]  

  • 6. De novo biosynthesis of dihydrosphingosine-1-phosphate by sphingosine kinase 1 in mammalian cells.
    Berdyshev EV; Gorshkova IA; Usatyuk P; Zhao Y; Saatian B; Hubbard W; Natarajan V
    Cell Signal; 2006 Oct; 18(10):1779-92. PubMed ID: 16529909
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-function analysis of lipid substrates and inhibitors of sphingosine kinases.
    Adams DR; Pyne S; Pyne NJ
    Cell Signal; 2020 Dec; 76():109806. PubMed ID: 33035646
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sphingosine kinase 1 (SK1) allosteric inhibitors that target the dimerization site.
    Bayraktar O; Ozkirimli E; Ulgen K
    Comput Biol Chem; 2017 Aug; 69():64-76. PubMed ID: 28587987
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The cross roles of sphingosine kinase 1/2 and ceramide glucosyltransferase in cell growth and death.
    Qin J; Kilkus JP; Dawson G
    Biochem Biophys Res Commun; 2018 Jun; 500(3):597-602. PubMed ID: 29673590
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Roles, regulation and inhibitors of sphingosine kinase 2.
    Neubauer HA; Pitson SM
    FEBS J; 2013 Nov; 280(21):5317-36. PubMed ID: 23638983
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular docking and molecular dynamics studies reveal structural basis of inhibition and selectivity of inhibitors EGCG and OSU-03012 toward glucose regulated protein-78 (GRP78) overexpressed in glioblastoma.
    Bhattacharjee R; Devi A; Mishra S
    J Mol Model; 2015 Oct; 21(10):272. PubMed ID: 26419972
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ablation of sphingosine kinase-2 inhibits tumor cell proliferation and migration.
    Gao P; Smith CD
    Mol Cancer Res; 2011 Nov; 9(11):1509-19. PubMed ID: 21896638
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A selective ATP-competitive sphingosine kinase inhibitor demonstrates anti-cancer properties.
    Pitman MR; Powell JA; Coolen C; Moretti PA; Zebol JR; Pham DH; Finnie JW; Don AS; Ebert LM; Bonder CS; Gliddon BL; Pitson SM
    Oncotarget; 2015 Mar; 6(9):7065-83. PubMed ID: 25788259
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of the Drosophila sphingosine kinases and requirement for Sk2 in normal reproductive function.
    Herr DR; Fyrst H; Creason MB; Phan VH; Saba JD; Harris GL
    J Biol Chem; 2004 Mar; 279(13):12685-94. PubMed ID: 14722126
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The sphingosine kinase 1/sphingosine-1-phosphate pathway mediates COX-2 induction and PGE2 production in response to TNF-alpha.
    Pettus BJ; Bielawski J; Porcelli AM; Reames DL; Johnson KR; Morrow J; Chalfant CE; Obeid LM; Hannun YA
    FASEB J; 2003 Aug; 17(11):1411-21. PubMed ID: 12890694
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sphingosine kinase 1 protects against renal ischemia-reperfusion injury in mice by sphingosine-1-phosphate1 receptor activation.
    Park SW; Kim M; Kim M; D'Agati VD; Lee HT
    Kidney Int; 2011 Dec; 80(12):1315-27. PubMed ID: 21849969
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of dansyl labeled sphingosine kinase 1 inhibitor.
    Park EY; Lee T; Oh YS; Lee JY; Shrestha J; Hong SW; Jin YJ; Jo G; Kim S; Hwang GT; Han DS; Baek DJ
    Chem Phys Lipids; 2018 Sep; 215():29-33. PubMed ID: 30044952
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sphingosine kinase as a regulator of calcium entry through autocrine sphingosine 1-phosphate signaling in thyroid FRTL-5 cells.
    Gratschev D; Löf C; Heikkilä J; Björkbom A; Sukumaran P; Hinkkanen A; Slotte JP; Törnquist K
    Endocrinology; 2009 Nov; 150(11):5125-34. PubMed ID: 19797403
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular dynamics simulation and free energy calculation studies of kinase inhibitors binding to active and inactive conformations of VEGFR-2.
    Wu X; Wan S; Wang G; Jin H; Li Z; Tian Y; Zhu Z; Zhang J
    J Mol Graph Model; 2015 Mar; 56():103-12. PubMed ID: 25594497
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure and catalytic function of sphingosine kinases: analysis by site-directed mutagenesis and enzyme kinetics.
    Baker DL; Pham TC; Sparks MA
    Biochim Biophys Acta; 2013 Jan; 1831(1):139-46. PubMed ID: 23000541
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.