316 related articles for article (PubMed ID: 26930604)
1. Impaired Inactivation of L-Type Ca2+ Current as a Potential Mechanism for Variable Arrhythmogenic Liability of HERG K+ Channel Blocking Drugs.
Kim JG; Sung DJ; Kim HJ; Park SW; Won KJ; Kim B; Shin HC; Kim KS; Leem CH; Zhang YH; Cho H; Bae YM
PLoS One; 2016; 11(3):e0149198. PubMed ID: 26930604
[TBL] [Abstract][Full Text] [Related]
2. Screening for acute IKr block is insufficient to detect torsades de pointes liability: role of late sodium current.
Yang T; Chun YW; Stroud DM; Mosley JD; Knollmann BC; Hong C; Roden DM
Circulation; 2014 Jul; 130(3):224-34. PubMed ID: 24895457
[TBL] [Abstract][Full Text] [Related]
3. Comparative pharmacology of guinea pig cardiac myocyte and cloned hERG (I(Kr)) channel.
Davie C; Pierre-Valentin J; Pollard C; Standen N; Mitcheson J; Alexander P; Thong B
J Cardiovasc Electrophysiol; 2004 Nov; 15(11):1302-9. PubMed ID: 15574182
[TBL] [Abstract][Full Text] [Related]
4. Selective block of IKs plays a significant role in MAP triangulation induced by IKr block in isolated rabbit heart.
Guérard NC; Traebert M; Suter W; Dumotier BM
J Pharmacol Toxicol Methods; 2008; 58(1):32-40. PubMed ID: 18582585
[TBL] [Abstract][Full Text] [Related]
5. Effects of L-type calcium channel and human ether-a-go-go related gene blockers on the electrical activity of the human heart: a simulation study.
Zemzemi N; Rodriguez B
Europace; 2015 Feb; 17(2):326-33. PubMed ID: 25228500
[TBL] [Abstract][Full Text] [Related]
6. Evaluation of Possible Proarrhythmic Potency: Comparison of the Effect of Dofetilide, Cisapride, Sotalol, Terfenadine, and Verapamil on hERG and Native IKr Currents and on Cardiac Action Potential.
Orvos P; Kohajda Z; Szlovák J; Gazdag P; Árpádffy-Lovas T; Tóth D; Geramipour A; Tálosi L; Jost N; Varró A; Virág L
Toxicol Sci; 2019 Apr; 168(2):365-380. PubMed ID: 30561737
[TBL] [Abstract][Full Text] [Related]
7. Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Wiśniowska B; Mendyk A; Fijorek K; Glinka A; Polak S
J Appl Toxicol; 2012 Oct; 32(10):858-66. PubMed ID: 22761000
[TBL] [Abstract][Full Text] [Related]
8. Mechanisms of QT prolongation by buprenorphine cannot be explained by direct hERG channel block.
Tran PN; Sheng J; Randolph AL; Baron CA; Thiebaud N; Ren M; Wu M; Johannesen L; Volpe DA; Patel D; Blinova K; Strauss DG; Wu WW
PLoS One; 2020; 15(11):e0241362. PubMed ID: 33157550
[TBL] [Abstract][Full Text] [Related]
9. Effect of azelastine on cardiac repolarization of guinea-pig cardiomyocytes, hERG K⁺ channel, and human L-type and T-type Ca²⁺ channel.
Park MH; Lee SH; Chu DH; Won KH; Choi BH; Choe H; Jo SH
J Pharmacol Sci; 2013 Sep; 123(1):67-77. PubMed ID: 24005046
[TBL] [Abstract][Full Text] [Related]
10. Mechanisms of gefitinib-induced QT prolongation.
Jie LJ; Li YD; Zhang HQ; Mao L; Xie HB; Zhou FG; Zhou TL; Xie D; Lin JL; Li GY; Cai BN; Zhang YH; Wang Y
Eur J Pharmacol; 2021 Nov; 910():174441. PubMed ID: 34474028
[TBL] [Abstract][Full Text] [Related]
11. Dehydroevodiamine and hortiamine, alkaloids from the traditional Chinese herbal drug Evodia rutaecarpa, are I
Baburin I; Varkevisser R; Schramm A; Saxena P; Beyl S; Szkokan P; Linder T; Stary-Weinzinger A; van der Heyden MAG; Houtman M; Takanari H; Jonsson M; Beekman JHD; Hamburger M; Vos MA; Hering S
Pharmacol Res; 2018 May; 131():150-163. PubMed ID: 29477480
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of human ether-a-go-go-related gene K+ channel and IKr of guinea pig cardiomyocytes by antipsychotic drug trifluoperazine.
Choi SY; Koh YS; Jo SH
J Pharmacol Exp Ther; 2005 May; 313(2):888-95. PubMed ID: 15722405
[TBL] [Abstract][Full Text] [Related]
13. Blockade of K+ and Ca2+ channels by azole antifungal agents in neonatal rat ventricular myocytes.
Sung DJ; Kim JG; Won KJ; Kim B; Shin HC; Park JY; Bae YM
Biol Pharm Bull; 2012; 35(9):1469-75. PubMed ID: 22975497
[TBL] [Abstract][Full Text] [Related]
14. Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle.
Jost N; Virág L; Bitay M; Takács J; Lengyel C; Biliczki P; Nagy Z; Bogáts G; Lathrop DA; Papp JG; Varró A
Circulation; 2005 Sep; 112(10):1392-9. PubMed ID: 16129791
[TBL] [Abstract][Full Text] [Related]
15. The antiestrogen tamoxifen blocks the delayed rectifier potassium current, IKr, in rabbit ventricular myocytes.
Liu XK; Katchman A; Ebert SN; Woosley RL
J Pharmacol Exp Ther; 1998 Dec; 287(3):877-83. PubMed ID: 9864267
[TBL] [Abstract][Full Text] [Related]
16. Inhibitory effect of erythromycin on potassium currents in rat ventricular myocytes in comparison with disopyramide.
Hanada E; Ohtani H; Hirota M; Uemura N; Nakaya H; Kotaki H; Sato H; Yamada Y; Iga T
J Pharm Pharmacol; 2003 Jul; 55(7):995-1002. PubMed ID: 12906757
[TBL] [Abstract][Full Text] [Related]
17. Does terfenadine-induced ventricular tachycardia/fibrillation directly relate to its QT prolongation and Torsades de Pointes?
Lu HR; Hermans AN; Gallacher DJ
Br J Pharmacol; 2012 Jun; 166(4):1490-502. PubMed ID: 22300168
[TBL] [Abstract][Full Text] [Related]
18. H(1) antihistamine drug promethazine directly blocks hERG K(+) channel.
Jo SH; Hong HK; Chong SH; Lee HS; Choe H
Pharmacol Res; 2009 Nov; 60(5):429-37. PubMed ID: 19497368
[TBL] [Abstract][Full Text] [Related]
19. Cardiac glycosides as novel inhibitors of human ether-a-go-go-related gene channel trafficking.
Wang L; Wible BA; Wan X; Ficker E
J Pharmacol Exp Ther; 2007 Feb; 320(2):525-34. PubMed ID: 17095614
[TBL] [Abstract][Full Text] [Related]
20. Human ether-a-go-go-related (HERG) gene and ATP-sensitive potassium channels as targets for adverse drug effects.
Zünkler BJ
Pharmacol Ther; 2006 Oct; 112(1):12-37. PubMed ID: 16647758
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
