241 related articles for article (PubMed ID: 26934697)
1. Biochemical Screening of Five Protein Kinases from Plasmodium falciparum against 14,000 Cell-Active Compounds.
Crowther GJ; Hillesland HK; Keyloun KR; Reid MC; Lafuente-Monasterio MJ; Ghidelli-Disse S; Leonard SE; He P; Jones JC; Krahn MM; Mo JS; Dasari KS; Fox AM; Boesche M; El Bakkouri M; Rivas KL; Leroy D; Hui R; Drewes G; Maly DJ; Van Voorhis WC; Ojo KK
PLoS One; 2016; 11(3):e0149996. PubMed ID: 26934697
[TBL] [Abstract][Full Text] [Related]
2. Imidazopyridazine Inhibitors of Plasmodium falciparum Calcium-Dependent Protein Kinase 1 Also Target Cyclic GMP-Dependent Protein Kinase and Heat Shock Protein 90 To Kill the Parasite at Different Stages of Intracellular Development.
Green JL; Moon RW; Whalley D; Bowyer PW; Wallace C; Rochani A; Nageshan RK; Howell SA; Grainger M; Jones HM; Ansell KH; Chapman TM; Taylor DL; Osborne SA; Baker DA; Tatu U; Holder AA
Antimicrob Agents Chemother; 2015 Dec; 60(3):1464-75. PubMed ID: 26711771
[TBL] [Abstract][Full Text] [Related]
3. Plasmodium falciparum protein kinase as a potential therapeutic target for antimalarial drugs development.
Mahmud F; Lee PC; Abdul Wahab H; Mustaffa KMF; Leow CH; Azhar R; Lai NS
Trop Biomed; 2020 Sep; 37(3):822-841. PubMed ID: 33612795
[TBL] [Abstract][Full Text] [Related]
4. Biochemical and antiparasitic properties of inhibitors of the Plasmodium falciparum calcium-dependent protein kinase PfCDPK1.
Ansell KH; Jones HM; Whalley D; Hearn A; Taylor DL; Patin EC; Chapman TM; Osborne SA; Wallace C; Birchall K; Large J; Bouloc N; Smiljanic-Hurley E; Clough B; Moon RW; Green JL; Holder AA
Antimicrob Agents Chemother; 2014 Oct; 58(10):6032-43. PubMed ID: 25070106
[TBL] [Abstract][Full Text] [Related]
5. Artificial Intelligence Applied to the Rapid Identification of New Antimalarial Candidates with Dual-Stage Activity.
Lima MNN; Borba JVB; Cassiano GC; Mottin M; Mendonça SS; Silva AC; Tomaz KCP; Calit J; Bargieri DY; Costa FTM; Andrade CH
ChemMedChem; 2021 Apr; 16(7):1093-1103. PubMed ID: 33247522
[TBL] [Abstract][Full Text] [Related]
6. Development of novel anti-malarial from structurally diverse library of molecules, targeting plant-like CDPK1, a multistage growth regulator of P. falciparum.
Jain R; Gupta S; Munde M; Pati S; Singh S
Biochem J; 2020 May; 477(10):1951-1970. PubMed ID: 32401306
[TBL] [Abstract][Full Text] [Related]
7. Identification via a Parallel Hit Progression Strategy of Improved Small Molecule Inhibitors of the Malaria Purine Uptake Transporter that Inhibit
Sosa Y; Deniskin R; Frame IJ; Steiginga MS; Bandyopadhyay D; Graybill TL; Kallal LA; Ouellette MT; Pope AJ; Widdowson KL; Young RJ; Akabas MH
ACS Infect Dis; 2019 Oct; 5(10):1738-1753. PubMed ID: 31373203
[TBL] [Abstract][Full Text] [Related]
8. Reduced Activity of Mutant Calcium-Dependent Protein Kinase 1 Is Compensated in Plasmodium falciparum through the Action of Protein Kinase G.
Bansal A; Ojo KK; Mu J; Maly DJ; Van Voorhis WC; Miller LH
mBio; 2016 Dec; 7(6):. PubMed ID: 27923926
[TBL] [Abstract][Full Text] [Related]
9. Discovery of Dual-Stage Malaria Inhibitors with New Targets.
Raphemot R; Lafuente-Monasterio MJ; Gamo-Benito FJ; Clardy J; Derbyshire ER
Antimicrob Agents Chemother; 2015 Dec; 60(3):1430-7. PubMed ID: 26666931
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of the SR protein-phosphorylating CLK kinases of Plasmodium falciparum impairs blood stage replication and malaria transmission.
Kern S; Agarwal S; Huber K; Gehring AP; Strödke B; Wirth CC; Brügl T; Abodo LO; Dandekar T; Doerig C; Fischer R; Tobin AB; Alam MM; Bracher F; Pradel G
PLoS One; 2014; 9(9):e105732. PubMed ID: 25188378
[TBL] [Abstract][Full Text] [Related]
11. In silico Screening and Evaluation of Plasmodium falciparum Protein Kinase 5 (PK5) Inhibitors.
Eubanks AL; Perkins MM; Sylvester K; Ganley JG; Posfai D; Sanschargrin PC; Hong J; Sliz P; Derbyshire ER
ChemMedChem; 2018 Dec; 13(23):2479-2483. PubMed ID: 30328274
[TBL] [Abstract][Full Text] [Related]
12. Preliminary LC-MS Based Screening for Inhibitors of Plasmodium falciparum Thioredoxin Reductase (PfTrxR) among a Set of Antimalarials from the Malaria Box.
Tiwari NK; Reynolds PJ; Calderón AI
Molecules; 2016 Mar; 21(4):424. PubMed ID: 27043496
[TBL] [Abstract][Full Text] [Related]
13. The motor complex of Plasmodium falciparum: phosphorylation by a calcium-dependent protein kinase.
Green JL; Rees-Channer RR; Howell SA; Martin SR; Knuepfer E; Taylor HM; Grainger M; Holder AA
J Biol Chem; 2008 Nov; 283(45):30980-9. PubMed ID: 18768477
[TBL] [Abstract][Full Text] [Related]
14. Expression of the essential Kinase PfCDPK1 from Plasmodium falciparum in Toxoplasma gondii facilitates the discovery of novel antimalarial drugs.
Gaji RY; Checkley L; Reese ML; Ferdig MT; Arrizabalaga G
Antimicrob Agents Chemother; 2014 May; 58(5):2598-607. PubMed ID: 24550330
[TBL] [Abstract][Full Text] [Related]
15. Plasmodium kinases as targets for new-generation antimalarials.
Lucet IS; Tobin A; Drewry D; Wilks AF; Doerig C
Future Med Chem; 2012 Dec; 4(18):2295-310. PubMed ID: 23234552
[TBL] [Abstract][Full Text] [Related]
16. Substituted imidazopyridazines are potent and selective inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1).
Chapman TM; Osborne SA; Bouloc N; Large JM; Wallace C; Birchall K; Ansell KH; Jones HM; Taylor D; Clough B; Green JL; Holder AA
Bioorg Med Chem Lett; 2013 May; 23(10):3064-9. PubMed ID: 23570789
[TBL] [Abstract][Full Text] [Related]
17. A specific inhibitor of PfCDPK4 blocks malaria transmission: chemical-genetic validation.
Ojo KK; Eastman RT; Vidadala R; Zhang Z; Rivas KL; Choi R; Lutz JD; Reid MC; Fox AM; Hulverson MA; Kennedy M; Isoherranen N; Kim LM; Comess KM; Kempf DJ; Verlinde CL; Su XZ; Kappe SH; Maly DJ; Fan E; Van Voorhis WC
J Infect Dis; 2014 Jan; 209(2):275-84. PubMed ID: 24123773
[TBL] [Abstract][Full Text] [Related]
18. Targeting the Plasmodium vivax equilibrative nucleoside transporter 1 (PvENT1) for antimalarial drug development.
Deniskin R; Frame IJ; Sosa Y; Akabas MH
Int J Parasitol Drugs Drug Resist; 2016 Apr; 6(1):1-11. PubMed ID: 26862473
[TBL] [Abstract][Full Text] [Related]
19. Invasion of hepatocytes by Plasmodium sporozoites requires cGMP-dependent protein kinase and calcium dependent protein kinase 4.
Govindasamy K; Jebiwott S; Jaijyan DK; Davidow A; Ojo KK; Van Voorhis WC; Brochet M; Billker O; Bhanot P
Mol Microbiol; 2016 Oct; 102(2):349-363. PubMed ID: 27425827
[TBL] [Abstract][Full Text] [Related]
20. 3,5-bis(benzylidene)-4-piperidones and related N-acyl analogs: a novel cluster of antimalarials targeting the liver stage of Plasmodium falciparum.
Das U; Singh RS; Alcorn J; Hickman MR; Sciotti RJ; Leed SE; Lee PJ; Roncal N; Dimmock JR
Bioorg Med Chem; 2013 Dec; 21(23):7250-6. PubMed ID: 24139941
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]