BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

576 related articles for article (PubMed ID: 26939044)

  • 1. New design of nucleotide excision repair (NER) inhibitors for combination cancer therapy.
    Gentile F; Tuszynski JA; Barakat KH
    J Mol Graph Model; 2016 Apr; 65():71-82. PubMed ID: 26939044
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Virtual screening and biological evaluation of inhibitors targeting the XPA-ERCC1 interaction.
    Barakat KH; Jordheim LP; Perez-Pineiro R; Wishart D; Dumontet C; Tuszynski JA
    PLoS One; 2012; 7(12):e51329. PubMed ID: 23272099
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Computational Characterization of Small Molecules Binding to the Human XPF Active Site and Virtual Screening to Identify Potential New DNA Repair Inhibitors Targeting the ERCC1-XPF Endonuclease.
    Gentile F; Barakat KH; Tuszynski JA
    Int J Mol Sci; 2018 Apr; 19(5):. PubMed ID: 29710850
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A truncated human xeroderma pigmentosum complementation group A protein expressed from an adenovirus sensitizes human tumor cells to ultraviolet light and cisplatin.
    Rosenberg E; Taher MM; Kuemmerle NB; Farnsworth J; Valerie K
    Cancer Res; 2001 Jan; 61(2):764-70. PubMed ID: 11212280
    [TBL] [Abstract][Full Text] [Related]  

  • 5. XPA versus ERCC1 as chemosensitising agents to cisplatin and mitomycin C in prostate cancer cells: role of ERCC1 in homologous recombination repair.
    Cummings M; Higginbottom K; McGurk CJ; Wong OG; Köberle B; Oliver RT; Masters JR
    Biochem Pharmacol; 2006 Jul; 72(2):166-75. PubMed ID: 16756962
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of an inhibitory dynamic pharmacophore for the ERCC1-XPA interaction using a combined molecular dynamics and virtual screening approach.
    Barakat KH; Torin Huzil J; Luchko T; Jordheim L; Dumontet C; Tuszynski J
    J Mol Graph Model; 2009 Sep; 28(2):113-30. PubMed ID: 19473860
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cell cycle checkpoint abrogator UCN-01 inhibits DNA repair: association with attenuation of the interaction of XPA and ERCC1 nucleotide excision repair proteins.
    Jiang H; Yang LY
    Cancer Res; 1999 Sep; 59(18):4529-34. PubMed ID: 10493501
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Expression of domains for protein-protein interaction of nucleotide excision repair proteins modifies cancer cell sensitivity to platinum derivatives and genomic stability.
    Jordheim LP; Cros-Perrial E; Matera EL; Bouledrak K; Dumontet C
    Clin Exp Pharmacol Physiol; 2014 Oct; 41(10):817-24. PubMed ID: 25115435
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Small Molecule Antagonists of the DNA Repair ERCC1/XPA Protein-Protein Interaction.
    Obermann R; Yemane B; Jarvis C; Franco FM; Kyriukha Y; Nolan W; Gohara B; Krezel AM; Wildman SA; Janetka JW
    ChemMedChem; 2024 Apr; 19(8):e202300648. PubMed ID: 38300970
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Functional and physical interactions between ERCC1 and MSH2 complexes for resistance to cis-diamminedichloroplatinum(II) in mammalian cells.
    Lan L; Hayashi T; Rabeya RM; Nakajima S; Kanno Si; Takao M; Matsunaga T; Yoshino M; Ichikawa M; Riele Ht; Tsuchiya S; Tanaka K; Yasui A
    DNA Repair (Amst); 2004 Feb; 3(2):135-43. PubMed ID: 14706347
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of novel small molecule inhibitors of the XPA protein using in silico based screening.
    Neher TM; Shuck SC; Liu JY; Zhang JT; Turchi JJ
    ACS Chem Biol; 2010 Oct; 5(10):953-65. PubMed ID: 20662484
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cyclosporin A inhibits nucleotide excision repair via downregulation of the xeroderma pigmentosum group A and G proteins, which is mediated by calcineurin inhibition.
    Kuschal C; Thoms KM; Boeckmann L; Laspe P; Apel A; Schön MP; Emmert S
    Exp Dermatol; 2011 Oct; 20(10):795-9. PubMed ID: 21707758
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural basis for the recruitment of ERCC1-XPF to nucleotide excision repair complexes by XPA.
    Tsodikov OV; Ivanov D; Orelli B; Staresincic L; Shoshani I; Oberman R; Schärer OD; Wagner G; Ellenberger T
    EMBO J; 2007 Nov; 26(22):4768-76. PubMed ID: 17948053
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The XPA-binding domain of ERCC1 is required for nucleotide excision repair but not other DNA repair pathways.
    Orelli B; McClendon TB; Tsodikov OV; Ellenberger T; Niedernhofer LJ; Schärer OD
    J Biol Chem; 2010 Feb; 285(6):3705-3712. PubMed ID: 19940136
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Conformational determinants for the recruitment of ERCC1 by XPA in the nucleotide excision repair (NER) Pathway: structure and dynamics of the XPA binding motif.
    Fadda E
    Biophys J; 2013 Jun; 104(11):2503-11. PubMed ID: 23746523
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular docking and molecular dynamics study on the effect of ERCC1 deleterious polymorphisms in ERCC1-XPF heterodimer.
    Priya Doss CG; Nagasundaram N
    Appl Biochem Biotechnol; 2014 Feb; 172(3):1265-81. PubMed ID: 24158589
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Computer-aided drug design of small molecule inhibitors of the ERCC1-XPF protein-protein interaction.
    Gentile F; Elmenoufy AH; Ciniero G; Jay D; Karimi-Busheri F; Barakat KH; Weinfeld M; West FG; Tuszynski JA
    Chem Biol Drug Des; 2020 Apr; 95(4):460-471. PubMed ID: 31891209
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metal binding mediated conformational change of XPA protein:a potential cytotoxic mechanism of nickel in the nucleotide excision repair.
    Hu J; Hu Z; Zhang Y; Gou X; Mu Y; Wang L; Xie XQ
    J Mol Model; 2016 Jul; 22(7):156. PubMed ID: 27307058
    [TBL] [Abstract][Full Text] [Related]  

  • 19. XPA: DNA Repair Protein of Significant Clinical Importance.
    Borszéková Pulzová L; Ward TA; Chovanec M
    Int J Mol Sci; 2020 Mar; 21(6):. PubMed ID: 32235701
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The role of conformational selection in the molecular recognition of the wild type and mutants XPA67-80 peptides by ERCC1.
    Fadda E
    Proteins; 2015 Jul; 83(7):1341-51. PubMed ID: 25973722
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.