BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 26941261)

  • 1. Small molecule inhibitors of the Dishevelled-CXXC5 interaction are new drug candidates for bone anabolic osteoporosis therapy.
    Kim HY; Choi S; Yoon JH; Lim HJ; Lee H; Choi J; Ro EJ; Heo JN; Lee W; No KT; Choi KY
    EMBO Mol Med; 2016 Apr; 8(4):375-87. PubMed ID: 26941261
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of a small-molecule inhibitor of Dvl-CXXC5 interaction by computational approaches.
    Ma S; Choi J; Jin X; Kim HY; Yun JH; Lee W; Choi KY; No KT
    J Comput Aided Mol Des; 2018 May; 32(5):643-655. PubMed ID: 29627878
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structure of the PDZ domain of mouse Dishevelled 1 and its interaction with CXXC5.
    Lee I; Choi S; Yun JH; Seo SH; Choi S; Choi KY; Lee W
    Biochem Biophys Res Commun; 2017 Apr; 485(3):584-590. PubMed ID: 27932247
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CXXC5 is a negative-feedback regulator of the Wnt/β-catenin pathway involved in osteoblast differentiation.
    Kim HY; Yoon JY; Yun JH; Cho KW; Lee SH; Rhee YM; Jung HS; Lim HJ; Lee H; Choi J; Heo JN; Lee W; No KT; Min D; Choi KY
    Cell Death Differ; 2015 Jun; 22(6):912-20. PubMed ID: 25633194
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Indirubin-3'-alkoxime derivatives for upregulation of Wnt signaling through dual inhibition of GSK-3β and the CXXC5-Dvl interaction.
    Song D; Lee Y; Kang MJ; Won Kim J; Lee SH; Choi KY; Kim EY; Lee K; Han G
    Bioorg Chem; 2022 Apr; 121():105664. PubMed ID: 35176556
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Dishevelled-binding protein CXXC5 negatively regulates cutaneous wound healing.
    Lee SH; Kim MY; Kim HY; Lee YM; Kim H; Nam KA; Roh MR; Min do S; Chung KY; Choi KY
    J Exp Med; 2015 Jun; 212(7):1061-80. PubMed ID: 26056233
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CXXC5 mediates growth plate senescence and is a target for enhancement of longitudinal bone growth.
    Choi S; Kim HY; Cha PH; Seo SH; Lee C; Choi Y; Shin W; Heo Y; Han G; Lee W; Choi KY
    Life Sci Alliance; 2019 Apr; 2(2):. PubMed ID: 30971423
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of CXXC5 function rescues Alzheimer's disease phenotypes by restoring Wnt/β-catenin signaling pathway.
    Yoon M; Kim H; Shin H; Lee H; Kang MJ; Park SH; Han G; Kim Y; Choi KY
    Pharmacol Res; 2023 Aug; 194():106836. PubMed ID: 37355147
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of CXXC5 function reverses obesity-related metabolic diseases.
    Seo SH; Kim E; Lee SH; Lee YH; Han DH; Go H; Seong JK; Choi KY
    Clin Transl Med; 2022 Apr; 12(4):e742. PubMed ID: 35384342
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of small-molecule compounds targeting the dishevelled PDZ domain by virtual screening and binding studies.
    Choi J; Ma S; Kim HY; Yun JH; Heo JN; Lee W; Choi KY; No KT
    Bioorg Med Chem; 2016 Aug; 24(15):3259-66. PubMed ID: 27112452
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting of CXXC5 by a Competing Peptide Stimulates Hair Regrowth and Wound-Induced Hair Neogenesis.
    Lee SH; Seo SH; Lee DH; Pi LQ; Lee WS; Choi KY
    J Invest Dermatol; 2017 Nov; 137(11):2260-2269. PubMed ID: 28595998
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Blockade of CXXC5-dishevelled interaction inhibits adipogenic differentiation, obesity, and insulin resistance in mice.
    Seo SH; Lee D; Lee SH; Choi KY
    Sci Rep; 2022 Nov; 12(1):20669. PubMed ID: 36450849
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CXXC5 is a novel BMP4-regulated modulator of Wnt signaling in neural stem cells.
    Andersson T; Södersten E; Duckworth JK; Cascante A; Fritz N; Sacchetti P; Cervenka I; Bryja V; Hermanson O
    J Biol Chem; 2009 Feb; 284(6):3672-81. PubMed ID: 19001364
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chrysosplenetin promotes osteoblastogenesis of bone marrow stromal cells via Wnt/β-catenin pathway and enhances osteogenesis in estrogen deficiency-induced bone loss.
    Hong G; He X; Shen Y; Chen X; Yang F; Yang P; Pang F; Han X; He W; Wei Q
    Stem Cell Res Ther; 2019 Aug; 10(1):277. PubMed ID: 31464653
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ginkgolide B promotes osteoblast differentiation via activation of canonical Wnt signalling and alleviates osteoporosis through a bone anabolic way.
    Zhu B; Xue F; Zhang C; Li G
    J Cell Mol Med; 2019 Aug; 23(8):5782-5793. PubMed ID: 31225702
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Indirubin-3'-oxime reverses bone loss in ovariectomized and hindlimb-unloaded mice via activation of the Wnt/β-catenin signaling.
    Zahoor M; Cha PH; Min do S; Choi KY
    J Bone Miner Res; 2014; 29(5):1196-205. PubMed ID: 24243753
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hovenia dulcis Thunb extract and its ingredient methyl vanillate activate Wnt/β-catenin pathway and increase bone mass in growing or ovariectomized mice.
    Cha PH; Shin W; Zahoor M; Kim HY; Min do S; Choi KY
    PLoS One; 2014; 9(1):e85546. PubMed ID: 24465596
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metabolic improvement and liver regeneration by inhibiting CXXC5 function for non-alcoholic steatohepatitis treatment.
    Seo SH; Kim E; Yoon M; Lee SH; Park BH; Choi KY
    Exp Mol Med; 2022 Sep; 54(9):1511-1523. PubMed ID: 36114279
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ubiquitin-Specific Protease 4 Antagonizes Osteoblast Differentiation Through Dishevelled.
    Zhou F; Li F; Fang P; Dai T; Yang B; van Dam H; Jia J; Zheng M; Zhang L
    J Bone Miner Res; 2016 Oct; 31(10):1888-1898. PubMed ID: 27128386
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD
    Ryu YC; Park J; Kim YR; Choi S; Kim GU; Kim E; Hwang Y; Kim H; Han G; Lee SH; Choi KY
    Cells; 2023 Feb; 12(4):. PubMed ID: 36831222
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.