BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

431 related articles for article (PubMed ID: 26942771)

  • 1. Development of Solid-Phase Site-Specific Conjugation and Its Application toward Generation of Dual Labeled Antibody and Fab Drug Conjugates.
    Puthenveetil S; Musto S; Loganzo F; Tumey LN; O'Donnell CJ; Graziani E
    Bioconjug Chem; 2016 Apr; 27(4):1030-9. PubMed ID: 26942771
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Utilizing Solid-Phase to Enable High-Throughput, Site-Specific Conjugation and Dual-Labeled Antibody and Fab Conjugates.
    Puthenveetil S
    Methods Mol Biol; 2020; 2078():99-112. PubMed ID: 31643052
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Specific Conjugation of the Hinge Region for Homogeneous Preparation of Antibody Fragment-Drug Conjugate: A Case Study for Doxorubicin-PEG-anti-CD20 Fab' Synthesis.
    Zhou Z; Zhang J; Zhang Y; Ma G; Su Z
    Bioconjug Chem; 2016 Jan; 27(1):238-46. PubMed ID: 26700095
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Advances in the Development of Site-Specific Antibody-Drug Conjugation.
    Zhou Q; Kim J
    Anticancer Agents Med Chem; 2015; 15(7):828-36. PubMed ID: 25731178
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Recent Chemical Approaches for Site-Specific Conjugation of Native Antibodies: Technologies toward Next-Generation Antibody-Drug Conjugates.
    Yamada K; Ito Y
    Chembiochem; 2019 Nov; 20(21):2729-2737. PubMed ID: 30973187
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antibody drug conjugates: design and selection of linker, payload and conjugation chemistry.
    McCombs JR; Owen SC
    AAPS J; 2015 Mar; 17(2):339-51. PubMed ID: 25604608
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Modulating Antibody-Drug Conjugate Payload Metabolism by Conjugation Site and Linker Modification.
    Su D; Kozak KR; Sadowsky J; Yu SF; Fourie-O'Donohue A; Nelson C; Vandlen R; Ohri R; Liu L; Ng C; He J; Davis H; Lau J; Del Rosario G; Cosino E; Cruz-Chuh JD; Ma Y; Zhang D; Darwish M; Cai W; Chen C; Zhou H; Lu J; Liu Y; Kaur S; Xu K; Pillow TH
    Bioconjug Chem; 2018 Apr; 29(4):1155-1167. PubMed ID: 29481745
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of Disulfide Bond Rebridged Fab-Drug Conjugates Prepared Using a Dual Maleimide Pyrrolobenzodiazepine Cytotoxic Payload.
    Ruddle BT; Fleming R; Wu H; Gao C; Dimasi N
    ChemMedChem; 2019 Jun; 14(12):1185-1195. PubMed ID: 30980702
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antibody-drug conjugates: recent advances in conjugation and linker chemistries.
    Tsuchikama K; An Z
    Protein Cell; 2018 Jan; 9(1):33-46. PubMed ID: 27743348
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Multivalent peptidic linker enables identification of preferred sites of conjugation for a potent thialanstatin antibody drug conjugate.
    Puthenveetil S; He H; Loganzo F; Musto S; Teske J; Green M; Tan X; Hosselet C; Lucas J; Tumey LN; Sapra P; Subramanyam C; O'Donnell CJ; Graziani EI
    PLoS One; 2017; 12(5):e0178452. PubMed ID: 28558059
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Thiolation of Q295: Site-Specific Conjugation of Hydrophobic Payloads without the Need for Genetic Engineering.
    Benjamin SR; Jackson CP; Fang S; Carlson DP; Guo Z; Tumey LN
    Mol Pharm; 2019 Jun; 16(6):2795-2807. PubMed ID: 31067063
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Aldehyde tag coupled with HIPS chemistry enables the production of ADCs conjugated site-specifically to different antibody regions with distinct in vivo efficacy and PK outcomes.
    Drake PM; Albers AE; Baker J; Banas S; Barfield RM; Bhat AS; de Hart GW; Garofalo AW; Holder P; Jones LC; Kudirka R; McFarland J; Zmolek W; Rabuka D
    Bioconjug Chem; 2014 Jul; 25(7):1331-41. PubMed ID: 24924618
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antibody-Drug Conjugates: Design, Formulation and Physicochemical Stability.
    Singh SK; Luisi DL; Pak RH
    Pharm Res; 2015 Nov; 32(11):3541-71. PubMed ID: 25986175
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Production of site-specific antibody-drug conjugates using optimized non-natural amino acids in a cell-free expression system.
    Zimmerman ES; Heibeck TH; Gill A; Li X; Murray CJ; Madlansacay MR; Tran C; Uter NT; Yin G; Rivers PJ; Yam AY; Wang WD; Steiner AR; Bajad SU; Penta K; Yang W; Hallam TJ; Thanos CD; Sato AK
    Bioconjug Chem; 2014 Feb; 25(2):351-61. PubMed ID: 24437342
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Proof of site-specificity of antibody-drug conjugates produced by chemical conjugation technology: AJICAP first generation.
    Matsuda Y; Malinao MC; Robles V; Song J; Yamada K; Mendelsohn BA
    J Chromatogr B Analyt Technol Biomed Life Sci; 2020 Mar; 1140():121981. PubMed ID: 32036254
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chemical Site-Specific Conjugation Platform to Improve the Pharmacokinetics and Therapeutic Index of Antibody-Drug Conjugates.
    Matsuda Y; Seki T; Yamada K; Ooba Y; Takahashi K; Fujii T; Kawaguchi S; Narita T; Nakayama A; Kitahara Y; Mendelsohn BA; Okuzumi T
    Mol Pharm; 2021 Nov; 18(11):4058-4066. PubMed ID: 34579528
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Location matters: site of conjugation modulates stability and pharmacokinetics of antibody drug conjugates.
    Strop P; Liu SH; Dorywalska M; Delaria K; Dushin RG; Tran TT; Ho WH; Farias S; Casas MG; Abdiche Y; Zhou D; Chandrasekaran R; Samain C; Loo C; Rossi A; Rickert M; Krimm S; Wong T; Chin SM; Yu J; Dilley J; Chaparro-Riggers J; Filzen GF; O'Donnell CJ; Wang F; Myers JS; Pons J; Shelton DL; Rajpal A
    Chem Biol; 2013 Feb; 20(2):161-7. PubMed ID: 23438745
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design and Validation of Linkers for Site-Specific Preparation of Antibody-Drug Conjugates Carrying Multiple Drug Copies Per Cysteine Conjugation Site.
    Kumar A; Mao S; Dimasi N; Gao C
    Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32961794
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Custom-Designed Affinity Capture LC-MS F(ab')2 Assay for Biotransformation Assessment of Site-Specific Antibody Drug Conjugates.
    Su D; Ng C; Khosraviani M; Yu SF; Cosino E; Kaur S; Xu K
    Anal Chem; 2016 Dec; 88(23):11340-11346. PubMed ID: 27779866
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antibody conjugates with unnatural amino acids.
    Hallam TJ; Wold E; Wahl A; Smider VV
    Mol Pharm; 2015 Jun; 12(6):1848-62. PubMed ID: 25898256
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.