343 related articles for article (PubMed ID: 26946220)
1. Application of the TGx-28.65 transcriptomic biomarker to classify genotoxic and non-genotoxic chemicals in human TK6 cells in the presence of rat liver S9.
Yauk CL; Buick JK; Williams A; Swartz CD; Recio L; Li HH; Fornace AJ; Thomson EM; Aubrecht J
Environ Mol Mutagen; 2016 May; 57(4):243-60. PubMed ID: 26946220
[TBL] [Abstract][Full Text] [Related]
2. Integration of metabolic activation with a predictive toxicogenomics signature to classify genotoxic versus nongenotoxic chemicals in human TK6 cells.
Buick JK; Moffat I; Williams A; Swartz CD; Recio L; Hyduke DR; Li HH; Fornace AJ; Aubrecht J; Yauk CL
Environ Mol Mutagen; 2015 Jul; 56(6):520-34. PubMed ID: 25733247
[TBL] [Abstract][Full Text] [Related]
3. Integration of the TGx-28.65 genomic biomarker with the flow cytometry micronucleus test to assess the genotoxicity of disperse orange and 1,2,4-benzenetriol in human TK6 cells.
Buick JK; Williams A; Kuo B; Wills JW; Swartz CD; Recio L; Li HH; Fornace AJ; Aubrecht J; Yauk CL
Mutat Res; 2017 Dec; 806():51-62. PubMed ID: 29017062
[TBL] [Abstract][Full Text] [Related]
4. Flow cytometric micronucleus assay and TGx-DDI transcriptomic biomarker analysis of ten genotoxic and non-genotoxic chemicals in human HepaRG™ cells.
Buick JK; Williams A; Gagné R; Swartz CD; Recio L; Ferguson SS; Yauk CL
Genes Environ; 2020; 42():5. PubMed ID: 32042365
[TBL] [Abstract][Full Text] [Related]
5. Assessment of the performance of the TGx-DDI biomarker to detect DNA damage-inducing agents using quantitative RT-PCR in TK6 cells.
Cho E; Buick JK; Williams A; Chen R; Li HH; Corton JC; Fornace AJ; Aubrecht J; Yauk CL
Environ Mol Mutagen; 2019 Mar; 60(2):122-133. PubMed ID: 30488505
[TBL] [Abstract][Full Text] [Related]
6. The TGx-28.65 biomarker online application for analysis of transcriptomics data to identify DNA damage-inducing chemicals in human cell cultures.
Jackson MA; Yang L; Lea I; Rashid A; Kuo B; Williams A; Lyn Yauk C; Fostel J
Environ Mol Mutagen; 2017 Aug; 58(7):529-535. PubMed ID: 28766826
[TBL] [Abstract][Full Text] [Related]
7. 3Rs-friendly approach to exogenous metabolic activation that supports high-throughput genetic toxicology testing.
Tian S; Cyr A; Zeise K; Bryce SM; Hall N; Bemis JC; Dertinger SD
Environ Mol Mutagen; 2020 Apr; 61(4):408-432. PubMed ID: 32039521
[TBL] [Abstract][Full Text] [Related]
8. A predictive toxicogenomics signature to classify genotoxic versus non-genotoxic chemicals in human TK6 cells.
Williams A; Buick JK; Moffat I; Swartz CD; Recio L; Hyduke DR; Li HH; Fornace AJ; Aubrecht J; Yauk CL
Data Brief; 2015 Dec; 5():77-83. PubMed ID: 26425668
[TBL] [Abstract][Full Text] [Related]
9. A Modern Genotoxicity Testing Paradigm: Integration of the High-Throughput CometChip® and the TGx-DDI Transcriptomic Biomarker in Human HepaRG™ Cell Cultures.
Buick JK; Williams A; Meier MJ; Swartz CD; Recio L; Gagné R; Ferguson SS; Engelward BP; Yauk CL
Front Public Health; 2021; 9():694834. PubMed ID: 34485225
[TBL] [Abstract][Full Text] [Related]
10. The utility of metabolic activation mixtures containing human hepatic post-mitochondrial supernatant (S9) for in vitro genetic toxicity assessment.
Cox JA; Fellows MD; Hashizume T; White PA
Mutagenesis; 2016 Mar; 31(2):117-30. PubMed ID: 26712374
[TBL] [Abstract][Full Text] [Related]
11. Development and validation of the TGx-HDACi transcriptomic biomarker to detect histone deacetylase inhibitors in human TK6 cells.
Cho E; Rowan-Carroll A; Williams A; Corton JC; Li HH; Fornace AJ; Hobbs CA; Yauk CL
Arch Toxicol; 2021 May; 95(5):1631-1645. PubMed ID: 33770205
[TBL] [Abstract][Full Text] [Related]
12. Evaluation of phenobarbital/beta-naphthoflavone as an alternative S9-induction regime to Aroclor 1254 in the rat for use in in vitro genotoxicity assays.
Callander RD; Mackay JM; Clay P; Elcombe CR; Elliott BM
Mutagenesis; 1995 Nov; 10(6):517-22. PubMed ID: 8596471
[TBL] [Abstract][Full Text] [Related]
13. Validation of a genotoxicity test based on p53R2 gene expression in human lymphoblastoid cells.
Mizota T; Ohno K; Yamada T
Mutat Res; 2011 Sep; 724(1-2):76-85. PubMed ID: 21704725
[TBL] [Abstract][Full Text] [Related]
14. Human liver S-9 metabolic activation: proficiency in cytogenetic assays and comparison with phenobarbital/beta-naphthoflavone or aroclor 1254 induced rat S-9.
Johnson TE; Umbenhauer DR; Galloway SM
Environ Mol Mutagen; 1996; 28(1):51-9. PubMed ID: 8698047
[TBL] [Abstract][Full Text] [Related]
15. A comparison of classical and 21st century genotoxicity tools: A proof of concept study of 18 chemicals comparing in vitro micronucleus, ToxTracker and genomics-based methods (TGx-DDI, whole genome clustering and connectivity mapping).
Allemang A; De Abrew KN; Shan YK; Krailler JM; Pfuhler S
Environ Mol Mutagen; 2021 Feb; 62(2):92-107. PubMed ID: 33252785
[TBL] [Abstract][Full Text] [Related]
16. Development and validation of a high-throughput transcriptomic biomarker to address 21st century genetic toxicology needs.
Li HH; Chen R; Hyduke DR; Williams A; Frötschl R; Ellinger-Ziegelbauer H; O'Lone R; Yauk CL; Aubrecht J; Fornace AJ
Proc Natl Acad Sci U S A; 2017 Dec; 114(51):E10881-E10889. PubMed ID: 29203651
[TBL] [Abstract][Full Text] [Related]
17. Salmonella/human S9 mutagenicity test: a collaborative study with 58 compounds.
Hakura A; Shimada H; Nakajima M; Sui H; Kitamoto S; Suzuki S; Satoh T
Mutagenesis; 2005 May; 20(3):217-28. PubMed ID: 15843387
[TBL] [Abstract][Full Text] [Related]
18. Effect of dietary casein levels on activation of promutagens in the spiral Salmonella mutagenicity assay. II. Studies with induced rat liver S9.
Woodall GM; Dauterman WC; DeMarini DM
Mutat Res; 1996 Jun; 360(2):127-43. PubMed ID: 8649465
[TBL] [Abstract][Full Text] [Related]
19. γH2AX and p53 responses in TK6 cells discriminate promutagens and nongenotoxicants in the presence of rat liver S9.
Bernacki DT; Bryce SM; Bemis JC; Kirkland D; Dertinger SD
Environ Mol Mutagen; 2016 Aug; 57(7):546-558. PubMed ID: 27364561
[TBL] [Abstract][Full Text] [Related]
20. Biomarkers of DNA damage response improve in vitro micronucleus assays by revealing genotoxic mode of action and reducing the occurrence of irrelevant positive results.
Avlasevich S; Pellegrin T; Godse M; Bryce S; Bemis J; Bajorski P; Dertinger S
Mutagenesis; 2021 Nov; 36(6):407-418. PubMed ID: 34718711
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
