322 related articles for article (PubMed ID: 26950371)
1. Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects.
Shukla S; Schmidt JC; Goldfarb KC; Cech TR; Parker R
Nat Struct Mol Biol; 2016 Apr; 23(4):286-92. PubMed ID: 26950371
[TBL] [Abstract][Full Text] [Related]
2. Chemical inhibition of PAPD5/7 rescues telomerase function and hematopoiesis in dyskeratosis congenita.
Shukla S; Jeong HC; Sturgeon CM; Parker R; Batista LFZ
Blood Adv; 2020 Jun; 4(12):2717-2722. PubMed ID: 32559291
[TBL] [Abstract][Full Text] [Related]
3. Posttranscriptional modulation of TERC by PAPD5 inhibition rescues hematopoietic development in dyskeratosis congenita.
Fok WC; Shukla S; Vessoni AT; Brenner KA; Parker R; Sturgeon CM; Batista LFZ
Blood; 2019 Mar; 133(12):1308-1312. PubMed ID: 30728146
[TBL] [Abstract][Full Text] [Related]
4. N-terminal residues of human dyskerin are required for interactions with telomerase RNA that prevent RNA degradation.
MacNeil DE; Lambert-Lanteigne P; Autexier C
Nucleic Acids Res; 2019 Jun; 47(10):5368-5380. PubMed ID: 30931479
[TBL] [Abstract][Full Text] [Related]
5. Single-molecule analysis of the human telomerase RNA.dyskerin interaction and the effect of dyskeratosis congenita mutations.
Ashbridge B; Orte A; Yeoman JA; Kirwan M; Vulliamy T; Dokal I; Klenerman D; Balasubramanian S
Biochemistry; 2009 Nov; 48(46):10858-65. PubMed ID: 19835419
[TBL] [Abstract][Full Text] [Related]
6. The C-terminal extension of dyskerin is a dyskeratosis congenita mutational hotspot that modulates interaction with telomerase RNA and subcellular localization.
Qin J; Garus A; Autexier C
Hum Mol Genet; 2024 Feb; 33(4):318-332. PubMed ID: 37879098
[TBL] [Abstract][Full Text] [Related]
7. Dyskeratosis congenita mutations in dyskerin SUMOylation consensus sites lead to impaired telomerase RNA accumulation and telomere defects.
Brault ME; Lauzon C; Autexier C
Hum Mol Genet; 2013 Sep; 22(17):3498-507. PubMed ID: 23660516
[TBL] [Abstract][Full Text] [Related]
8. The H/ACA complex disrupts triplex in hTR precursor to permit processing by RRP6 and PARN.
Tseng CK; Wang HF; Schroeder MR; Baumann P
Nat Commun; 2018 Dec; 9(1):5430. PubMed ID: 30575725
[TBL] [Abstract][Full Text] [Related]
9. Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease.
Roake CM; Chen L; Chakravarthy AL; Ferrell JE; Raffa GD; Artandi SE
Mol Cell; 2019 May; 74(4):688-700.e3. PubMed ID: 30930056
[TBL] [Abstract][Full Text] [Related]
10. Telomere biology disorders: time for moving towards the clinic?
Batista LFZ; Dokal I; Parker R
Trends Mol Med; 2022 Oct; 28(10):882-891. PubMed ID: 36057525
[TBL] [Abstract][Full Text] [Related]
11. The RNase PARN Controls the Levels of Specific miRNAs that Contribute to p53 Regulation.
Shukla S; Bjerke GA; Muhlrad D; Yi R; Parker R
Mol Cell; 2019 Mar; 73(6):1204-1216.e4. PubMed ID: 30770239
[TBL] [Abstract][Full Text] [Related]
12. PARN Modulates Y RNA Stability and Its 3'-End Formation.
Shukla S; Parker R
Mol Cell Biol; 2017 Oct; 37(20):. PubMed ID: 28760775
[TBL] [Abstract][Full Text] [Related]
13. Severity of X-linked dyskeratosis congenita (DKCX) cellular defects is not directly related to dyskerin (DKC1) activity in ribosomal RNA biogenesis or mRNA translation.
Thumati NR; Zeng XL; Au HH; Jang CJ; Jan E; Wong JM
Hum Mutat; 2013 Dec; 34(12):1698-707. PubMed ID: 24115260
[TBL] [Abstract][Full Text] [Related]
14. The accumulation and not the specific activity of telomerase ribonucleoprotein determines telomere maintenance deficiency in X-linked dyskeratosis congenita.
Zeng XL; Thumati NR; Fleisig HB; Hukezalie KR; Savage SA; Giri N; Alter BP; Wong JM
Hum Mol Genet; 2012 Feb; 21(4):721-9. PubMed ID: 22058290
[TBL] [Abstract][Full Text] [Related]
15. Defects in mTR stability and telomerase activity produced by the Dkc1 A353V mutation in dyskeratosis congenita are rescued by a peptide from the dyskerin TruB domain.
Machado-Pinilla R; Carrillo J; Manguan-Garcia C; Sastre L; Mentzer A; Gu BW; Mason PJ; Perona R
Clin Transl Oncol; 2012 Oct; 14(10):755-63. PubMed ID: 22855157
[TBL] [Abstract][Full Text] [Related]
16. Domain specific mutations in dyskerin disrupt 3' end processing of scaRNA13.
Nagpal N; Tai AK; Nandakumar J; Agarwal S
Nucleic Acids Res; 2022 Sep; 50(16):9413-9425. PubMed ID: 36018809
[TBL] [Abstract][Full Text] [Related]
17. Regulation of poly(a)-specific ribonuclease activity by reversible lysine acetylation.
Dejene EA; Li Y; Showkatian Z; Ling H; Seto E
J Biol Chem; 2020 Jul; 295(30):10255-10270. PubMed ID: 32457045
[TBL] [Abstract][Full Text] [Related]
18. A Polyadenylation-Dependent 3' End Maturation Pathway Is Required for the Synthesis of the Human Telomerase RNA.
Nguyen D; Grenier St-Sauveur V; Bergeron D; Dupuis-Sandoval F; Scott MS; Bachand F
Cell Rep; 2015 Dec; 13(10):2244-57. PubMed ID: 26628368
[TBL] [Abstract][Full Text] [Related]
19. Decreased dyskerin levels as a mechanism of telomere shortening in X-linked dyskeratosis congenita.
Parry EM; Alder JK; Lee SS; Phillips JA; Loyd JE; Duggal P; Armanios M
J Med Genet; 2011 May; 48(5):327-33. PubMed ID: 21415081
[TBL] [Abstract][Full Text] [Related]
20. Posttranscriptional manipulation of TERC reverses molecular hallmarks of telomere disease.
Boyraz B; Moon DH; Segal M; Muosieyiri MZ; Aykanat A; Tai AK; Cahan P; Agarwal S
J Clin Invest; 2016 Sep; 126(9):3377-82. PubMed ID: 27482890
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]