418 related articles for article (PubMed ID: 26956619)
1. ERK mediated upregulation of death receptor 5 overcomes the lack of p53 functionality in the diaminothiazole DAT1 induced apoptosis in colon cancer models: efficiency of DAT1 in Ras-Raf mutated cells.
Thamkachy R; Kumar R; Rajasekharan KN; Sengupta S
Mol Cancer; 2016 Mar; 15():22. PubMed ID: 26956619
[TBL] [Abstract][Full Text] [Related]
2. Upregulation of DR5 receptor by the diaminothiazole DAT1 [4-amino-5-benzoyl-2-(4-methoxy phenyl amino) thiazole] triggers an independent extrinsic pathway of apoptosis in colon cancer cells with compromised pro and antiapoptotic proteins.
Thomas SA; Vasudevan S; Thamkachy R; Lekshmi SU; Santhoshkumar TR; Rajasekharan KN; Sengupta S
Apoptosis; 2013 Jun; 18(6):713-26. PubMed ID: 23435998
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of B-Raf/MEK/ERK signaling suppresses DR5 expression and impairs response of cancer cells to DR5-mediated apoptosis and T cell-induced killing.
Oh YT; Deng J; Yue P; Owonikoko TK; Khuri FR; Sun SY
Oncogene; 2016 Jan; 35(4):459-67. PubMed ID: 25867065
[TBL] [Abstract][Full Text] [Related]
4. HOXA3 promotes tumor growth of human colon cancer through activating EGFR/Ras/Raf/MEK/ERK signaling pathway.
Zhang X; Liu G; Ding L; Jiang T; Shao S; Gao Y; Lu Y
J Cell Biochem; 2018 Mar; 119(3):2864-2874. PubMed ID: 29073728
[TBL] [Abstract][Full Text] [Related]
5. Asperolide A, a marine-derived tetranorditerpenoid, induces G2/M arrest in human NCI-H460 lung carcinoma cells, is mediated by p53-p21 stabilization and modulated by Ras/Raf/MEK/ERK signaling pathway.
Lv C; Sun W; Sun H; Wei S; Chen R; Wang B; Huang C
Mar Drugs; 2013 Jan; 11(2):316-31. PubMed ID: 23434831
[TBL] [Abstract][Full Text] [Related]
6. Wentilactone A as a novel potential antitumor agent induces apoptosis and G2/M arrest of human lung carcinoma cells, and is mediated by HRas-GTP accumulation to excessively activate the Ras/Raf/ERK/p53-p21 pathway.
Lv C; Hong Y; Miao L; Li C; Xu G; Wei S; Wang B; Huang C; Jiao B
Cell Death Dis; 2013 Dec; 4(12):e952. PubMed ID: 24309939
[TBL] [Abstract][Full Text] [Related]
7. Paradoxical activation of MEK/ERK signaling induced by B-Raf inhibition enhances DR5 expression and DR5 activation-induced apoptosis in Ras-mutant cancer cells.
Oh YT; Deng J; Yue P; Sun SY
Sci Rep; 2016 May; 6():26803. PubMed ID: 27222248
[TBL] [Abstract][Full Text] [Related]
8. Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance.
McCubrey JA; Steelman LS; Chappell WH; Abrams SL; Wong EW; Chang F; Lehmann B; Terrian DM; Milella M; Tafuri A; Stivala F; Libra M; Basecke J; Evangelisti C; Martelli AM; Franklin RA
Biochim Biophys Acta; 2007 Aug; 1773(8):1263-84. PubMed ID: 17126425
[TBL] [Abstract][Full Text] [Related]
9. Resistance to mitogen-activated protein kinase kinase (MEK) inhibitors correlates with up-regulation of the MEK/extracellular signal-regulated kinase pathway in hepatocellular carcinoma cells.
Yip-Schneider MT; Klein PJ; Wentz SC; Zeni A; Menze A; Schmidt CM
J Pharmacol Exp Ther; 2009 Jun; 329(3):1063-70. PubMed ID: 19258520
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of extracellular signal regulated kinase (ERK) leads to apoptosis inducing factor (AIF) mediated apoptosis in epithelial breast cancer cells: the lack of effect of ERK in p53 mediated copper induced apoptosis.
Ostrakhovitch EA; Cherian MG
J Cell Biochem; 2005 Aug; 95(6):1120-34. PubMed ID: 15880691
[TBL] [Abstract][Full Text] [Related]
11. Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.
McCubrey JA; Steelman LS; Abrams SL; Lee JT; Chang F; Bertrand FE; Navolanic PM; Terrian DM; Franklin RA; D'Assoro AB; Salisbury JL; Mazzarino MC; Stivala F; Libra M
Adv Enzyme Regul; 2006; 46():249-79. PubMed ID: 16854453
[TBL] [Abstract][Full Text] [Related]
12. 5-Fluorouracil signaling through a calcium-calmodulin-dependent pathway is required for p53 activation and apoptosis in colon carcinoma cells.
Can G; Akpinar B; Baran Y; Zhivotovsky B; Olsson M
Oncogene; 2013 Sep; 32(38):4529-38. PubMed ID: 23108402
[TBL] [Abstract][Full Text] [Related]
13. The transcription factor NFAT1 induces apoptosis through cooperation with Ras/Raf/MEK/ERK pathway and upregulation of TNF-α expression.
Robbs BK; Lucena PI; Viola JP
Biochim Biophys Acta; 2013 Aug; 1833(8):2016-28. PubMed ID: 23583303
[TBL] [Abstract][Full Text] [Related]
14. Oridonin induces G2/M arrest and apoptosis via activating ERK-p53 apoptotic pathway and inhibiting PTK-Ras-Raf-JNK survival pathway in murine fibrosarcoma L929 cells.
Cheng Y; Qiu F; Ye YC; Tashiro S; Onodera S; Ikejima T
Arch Biochem Biophys; 2009 Oct; 490(1):70-5. PubMed ID: 19699177
[TBL] [Abstract][Full Text] [Related]
15. Involvement of p53 and Raf/MEK/ERK pathways in hematopoietic drug resistance.
McCubrey JA; Abrams SL; Ligresti G; Misaghian N; Wong EW; Steelman LS; Bäsecke J; Troppmair J; Libra M; Nicoletti F; Molton S; McMahon M; Evangelisti C; Martelli AM
Leukemia; 2008 Nov; 22(11):2080-90. PubMed ID: 18685611
[TBL] [Abstract][Full Text] [Related]
16. FOXD3 is a tumor suppressor of colon cancer by inhibiting EGFR-Ras-Raf-MEK-ERK signal pathway.
Li K; Guo Q; Yang J; Chen H; Hu K; Zhao J; Zheng S; Pang X; Zhou S; Dang Y; Li L
Oncotarget; 2017 Jan; 8(3):5048-5056. PubMed ID: 27926503
[TBL] [Abstract][Full Text] [Related]
17. Dihydrosanguinarine suppresses pancreatic cancer cells via regulation of mut-p53/WT-p53 and the Ras/Raf/Mek/Erk pathway.
Wu SZ; Xu HC; Wu XL; Liu P; Shi YC; Pang P; Deng L; Zhou GX; Chen XY
Phytomedicine; 2019 Jun; 59():152895. PubMed ID: 30913453
[TBL] [Abstract][Full Text] [Related]
18. Calcium-activated RAF/MEK/ERK signaling pathway mediates p53-dependent apoptosis and is abrogated by alpha B-crystallin through inhibition of RAS activation.
Li DW; Liu JP; Mao YW; Xiang H; Wang J; Ma WY; Dong Z; Pike HM; Brown RE; Reed JC
Mol Biol Cell; 2005 Sep; 16(9):4437-53. PubMed ID: 16000378
[TBL] [Abstract][Full Text] [Related]
19. CrkL plays a role in SDF-1-induced activation of the Raf-1/MEK/Erk pathway through Ras and Rac to mediate chemotactic signaling in hematopoietic cells.
Arai A; Aoki M; Weihua Y; Jin A; Miura O
Cell Signal; 2006 Dec; 18(12):2162-71. PubMed ID: 16781119
[TBL] [Abstract][Full Text] [Related]
20. Involvement of Ras/Raf-1/ERK actions in the magnolol-induced upregulation of p21 and cell-cycle arrest in colon cancer cells.
Hsu YF; Lee TS; Lin SY; Hsu SP; Juan SH; Hsu YH; Zhong WB; Lee WS
Mol Carcinog; 2007 Apr; 46(4):275-83. PubMed ID: 17295239
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
