BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

218 related articles for article (PubMed ID: 26962022)

  • 1. A comprehensive analysis and functional characterization of naturally occurring non-synonymous variants of nuclear receptor PXR.
    Rana M; Devi S; Gourinath S; Goswami R; Tyagi RK
    Biochim Biophys Acta; 2016 Sep; 1859(9):1183-1197. PubMed ID: 26962022
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Acetylation of lysine 109 modulates pregnane X receptor DNA binding and transcriptional activity.
    Pasquel D; Doricakova A; Li H; Kortagere S; Krasowski MD; Biswas A; Walton WG; Redinbo MR; Dvorak Z; Mani S
    Biochim Biophys Acta; 2016 Sep; 1859(9):1155-1169. PubMed ID: 26855179
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional characterization of four naturally occurring variants of human pregnane X receptor (PXR): one variant causes dramatic loss of both DNA binding activity and the transactivation of the CYP3A4 promoter/enhancer region.
    Koyano S; Kurose K; Saito Y; Ozawa S; Hasegawa R; Komamura K; Ueno K; Kamakura S; Kitakaze M; Nakajima T; Matsumoto K; Akasawa A; Saito H; Sawada J
    Drug Metab Dispos; 2004 Jan; 32(1):149-54. PubMed ID: 14709632
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants.
    Zhang J; Kuehl P; Green ED; Touchman JW; Watkins PB; Daly A; Hall SD; Maurel P; Relling M; Brimer C; Yasuda K; Wrighton SA; Hancock M; Kim RB; Strom S; Thummel K; Russell CG; Hudson JR; Schuetz EG; Boguski MS
    Pharmacogenetics; 2001 Oct; 11(7):555-72. PubMed ID: 11668216
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes.
    Kandel BA; Thomas M; Winter S; Damm G; Seehofer D; Burk O; Schwab M; Zanger UM
    Biochim Biophys Acta; 2016 Sep; 1859(9):1218-1227. PubMed ID: 26994748
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel functions of PXR in cardiometabolic disease.
    Zhou C
    Biochim Biophys Acta; 2016 Sep; 1859(9):1112-1120. PubMed ID: 26924429
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RNA-Seq reveals common and unique PXR- and CAR-target gene signatures in the mouse liver transcriptome.
    Cui JY; Klaassen CD
    Biochim Biophys Acta; 2016 Sep; 1859(9):1198-1217. PubMed ID: 27113289
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The role of residues T248, Y249 and T422 in the function of human pregnane X receptor.
    Doricakova A; Novotna A; Vrzal R; Pavek P; Dvorak Z
    Arch Toxicol; 2013 Feb; 87(2):291-301. PubMed ID: 22976785
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A SUMO-acetyl switch in PXR biology.
    Cui W; Sun M; Zhang S; Shen X; Galeva N; Williams TD; Staudinger JL
    Biochim Biophys Acta; 2016 Sep; 1859(9):1170-1182. PubMed ID: 26883953
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nuclear receptor SHP dampens transcription function and abrogates mitotic chromatin association of PXR and ERα via intermolecular interactions.
    Kumar S; Vijayan R; Dash AK; Gourinath S; Tyagi RK
    Biochim Biophys Acta Gene Regul Mech; 2021 Mar; 1864(3):194683. PubMed ID: 33444783
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of hepatic energy metabolism by the nuclear receptor PXR.
    Hakkola J; Rysä J; Hukkanen J
    Biochim Biophys Acta; 2016 Sep; 1859(9):1072-1082. PubMed ID: 27041449
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in zebrafish (Danio rerio).
    Bainy AC; Kubota A; Goldstone JV; Lille-Langøy R; Karchner SI; Celander MC; Hahn ME; Goksøyr A; Stegeman JJ
    Aquat Toxicol; 2013 Oct; 142-143():447-57. PubMed ID: 24121122
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transcription regulation of nuclear receptor PXR: Role of SUMO-1 modification and NDSM in receptor function.
    Priyanka ; Kotiya D; Rana M; Subbarao N; Puri N; Tyagi RK
    Mol Cell Endocrinol; 2016 Jan; 420():194-207. PubMed ID: 26549688
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification and interplay of sequence specific DNA binding proteins involved in regulation of human Pregnane and Xenobiotic Receptor gene.
    Saradhi M; Kumari S; Rana M; Mukhopadhyay G; Tyagi RK
    Exp Cell Res; 2015 Dec; 339(2):187-96. PubMed ID: 26586566
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Influence of a critical single nucleotide polymorphism on nuclear receptor PXR-promoter function.
    Rana M; Coshic P; Goswami R; Tyagi RK
    Cell Biol Int; 2017 May; 41(5):570-576. PubMed ID: 28198586
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution.
    Jones SA; Moore LB; Shenk JL; Wisely GB; Hamilton GA; McKee DD; Tomkinson NC; LeCluyse EL; Lambert MH; Willson TM; Kliewer SA; Moore JT
    Mol Endocrinol; 2000 Jan; 14(1):27-39. PubMed ID: 10628745
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MicroRNA-30c-1-3p is a silencer of the pregnane X receptor by targeting the 3'-untranslated region and alters the expression of its target gene cytochrome P450 3A4.
    Vachirayonstien T; Yan B
    Biochim Biophys Acta; 2016 Sep; 1859(9):1238-1244. PubMed ID: 27085140
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Post-translational and post-transcriptional modifications of pregnane X receptor (PXR) in regulation of the cytochrome P450 superfamily.
    Smutny T; Mani S; Pavek P
    Curr Drug Metab; 2013 Dec; 14(10):1059-69. PubMed ID: 24329114
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mathematical Models in the Description of Pregnane X Receptor (PXR)-Regulated Cytochrome P450 Enzyme Induction.
    Tebbens JD; Azar M; Friedmann E; Lanzendörfer M; Pávek P
    Int J Mol Sci; 2018 Jun; 19(6):. PubMed ID: 29914136
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Screening for polymorphisms in the PXR gene in a Dutch population.
    Bosch TM; Deenen M; Pruntel R; Smits PH; Schellens JH; Beijnen JH; Meijerman I
    Eur J Clin Pharmacol; 2006 May; 62(5):395-9. PubMed ID: 16568343
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.