These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

344 related articles for article (PubMed ID: 26963025)

  • 1. Insulin-degrading enzyme secretion from astrocytes is mediated by an autophagy-based unconventional secretory pathway in Alzheimer disease.
    Son SM; Cha MY; Choi H; Kang S; Choi H; Lee MS; Park SA; Mook-Jung I
    Autophagy; 2016 May; 12(5):784-800. PubMed ID: 26963025
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Statins induce insulin-degrading enzyme secretion from astrocytes via an autophagy-based unconventional secretory pathway.
    Son SM; Kang S; Choi H; Mook-Jung I
    Mol Neurodegener; 2015 Oct; 10():56. PubMed ID: 26520569
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insulin-signaling Pathway Regulates the Degradation of Amyloid β-protein via Astrocytes.
    Yamamoto N; Ishikuro R; Tanida M; Suzuki K; Ikeda-Matsuo Y; Sobue K
    Neuroscience; 2018 Aug; 385():227-236. PubMed ID: 29932983
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Oxidative inactivation of amyloid beta-degrading proteases by cholesterol-enhanced mitochondrial stress.
    de Dios C; Bartolessis I; Roca-Agujetas V; Barbero-Camps E; Mari M; Morales A; Colell A
    Redox Biol; 2019 Sep; 26():101283. PubMed ID: 31376793
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Simvastatin and atorvastatin facilitates amyloid β-protein degradation in extracellular spaces by increasing neprilysin secretion from astrocytes through activation of MAPK/Erk1/2 pathways.
    Yamamoto N; Fujii Y; Kasahara R; Tanida M; Ohora K; Ono Y; Suzuki K; Sobue K
    Glia; 2016 Jun; 64(6):952-62. PubMed ID: 26875818
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Epigallocatechin gallate induces extracellular degradation of amyloid β-protein by increasing neprilysin secretion from astrocytes through activation of ERK and PI3K pathways.
    Yamamoto N; Shibata M; Ishikuro R; Tanida M; Taniguchi Y; Ikeda-Matsuo Y; Sobue K
    Neuroscience; 2017 Oct; 362():70-78. PubMed ID: 28844000
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Plaque-associated overexpression of insulin-degrading enzyme in the cerebral cortex of aged transgenic tg2576 mice with Alzheimer pathology.
    Leal MC; Dorfman VB; Gamba AF; Frangione B; Wisniewski T; Castaño EM; Sigurdsson EM; Morelli L
    J Neuropathol Exp Neurol; 2006 Oct; 65(10):976-87. PubMed ID: 17021402
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo.
    Farris W; Mansourian S; Chang Y; Lindsley L; Eckman EA; Frosch MP; Eckman CB; Tanzi RE; Selkoe DJ; Guenette S
    Proc Natl Acad Sci U S A; 2003 Apr; 100(7):4162-7. PubMed ID: 12634421
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Insulin-degrading enzyme sorting in exosomes: a secretory pathway for a key brain amyloid-beta degrading protease.
    Bulloj A; Leal MC; Xu H; Castaño EM; Morelli L
    J Alzheimers Dis; 2010; 19(1):79-95. PubMed ID: 20061628
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation.
    Qiu WQ; Walsh DM; Ye Z; Vekrellis K; Zhang J; Podlisny MB; Rosner MR; Safavi A; Hersh LB; Selkoe DJ
    J Biol Chem; 1998 Dec; 273(49):32730-8. PubMed ID: 9830016
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme.
    Vekrellis K; Ye Z; Qiu WQ; Walsh D; Hartley D; Chesneau V; Rosner MR; Selkoe DJ
    J Neurosci; 2000 Mar; 20(5):1657-65. PubMed ID: 10684867
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: review and hypothesis.
    Qiu WQ; Folstein MF
    Neurobiol Aging; 2006 Feb; 27(2):190-8. PubMed ID: 16399206
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion.
    Tamboli IY; Barth E; Christian L; Siepmann M; Kumar S; Singh S; Tolksdorf K; Heneka MT; Lütjohann D; Wunderlich P; Walter J
    J Biol Chem; 2010 Nov; 285(48):37405-14. PubMed ID: 20876579
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 6-Hydroxydopamine induces secretion of PARK7/DJ-1 via autophagy-based unconventional secretory pathway.
    Urano Y; Mori C; Fuji A; Konno K; Yamamoto T; Yashirogi S; Ando M; Saito Y; Noguchi N
    Autophagy; 2018; 14(11):1943-1958. PubMed ID: 30112966
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BRI2 protein regulates β-amyloid degradation by increasing levels of secreted insulin-degrading enzyme (IDE).
    Kilger E; Buehler A; Woelfing H; Kumar S; Kaeser SA; Nagarathinam A; Walter J; Jucker M; Coomaraswamy J
    J Biol Chem; 2011 Oct; 286(43):37446-57. PubMed ID: 21873424
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein.
    Farris W; Mansourian S; Leissring MA; Eckman EA; Bertram L; Eckman CB; Tanzi RE; Selkoe DJ
    Am J Pathol; 2004 Apr; 164(4):1425-34. PubMed ID: 15039230
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Insulin degrading enzyme contributes to the pathology in a mixed model of Type 2 diabetes and Alzheimer's disease: possible mechanisms of IDE in T2D and AD.
    Li H; Wu J; Zhu L; Sha L; Yang S; Wei J; Ji L; Tang X; Mao K; Cao L; Wei N; Xie W; Yang Z
    Biosci Rep; 2018 Feb; 38(1):. PubMed ID: 29222348
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aβ secretion and plaque formation depend on autophagy.
    Nilsson P; Loganathan K; Sekiguchi M; Matsuba Y; Hui K; Tsubuki S; Tanaka M; Iwata N; Saito T; Saido TC
    Cell Rep; 2013 Oct; 5(1):61-9. PubMed ID: 24095740
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Statins in unconventional secretion of insulin-degrading enzyme and degradation of the amyloid-β peptide.
    Glebov K; Walter J
    Neurodegener Dis; 2012; 10(1-4):309-12. PubMed ID: 22205103
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The catalytic domain of insulin-degrading enzyme forms a denaturant-resistant complex with amyloid beta peptide: implications for Alzheimer disease pathogenesis.
    Llovera RE; de Tullio M; Alonso LG; Leissring MA; Kaufman SB; Roher AE; de Prat Gay G; Morelli L; Castaño EM
    J Biol Chem; 2008 Jun; 283(25):17039-48. PubMed ID: 18411275
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.