421 related articles for article (PubMed ID: 26963853)
1. TGF-β activates APC through Cdh1 binding for Cks1 and Skp2 proteasomal destruction stabilizing p27kip1 for normal endometrial growth.
Pavlides SC; Lecanda J; Daubriac J; Pandya UM; Gama P; Blank S; Mittal K; Shukla P; Gold LI
Cell Cycle; 2016; 15(7):931-47. PubMed ID: 26963853
[TBL] [Abstract][Full Text] [Related]
2. Estrogen and progesterone regulate p27kip1 levels via the ubiquitin-proteasome system: pathogenic and therapeutic implications for endometrial cancer.
Huang KT; Pavlides SC; Lecanda J; Blank SV; Mittal KR; Gold LI
PLoS One; 2012; 7(9):e46072. PubMed ID: 23029392
[TBL] [Abstract][Full Text] [Related]
3. Inhibitors of SCF-Skp2/Cks1 E3 ligase block estrogen-induced growth stimulation and degradation of nuclear p27kip1: therapeutic potential for endometrial cancer.
Pavlides SC; Huang KT; Reid DA; Wu L; Blank SV; Mittal K; Guo L; Rothenberg E; Rueda B; Cardozo T; Gold LI
Endocrinology; 2013 Nov; 154(11):4030-45. PubMed ID: 24035998
[TBL] [Abstract][Full Text] [Related]
4. Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase.
Bashir T; Dorrello NV; Amador V; Guardavaccaro D; Pagano M
Nature; 2004 Mar; 428(6979):190-3. PubMed ID: 15014502
[TBL] [Abstract][Full Text] [Related]
5. Negative regulation of SCFSkp2 ubiquitin ligase by TGF-beta signaling.
Wang W; Ungermannova D; Jin J; Harper JW; Liu X
Oncogene; 2004 Feb; 23(5):1064-75. PubMed ID: 14676846
[TBL] [Abstract][Full Text] [Related]
6. SKP2 and CKS1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosis.
Calvisi DF; Ladu S; Pinna F; Frau M; Tomasi ML; Sini M; Simile MM; Bonelli P; Muroni MR; Seddaiu MA; Lim DS; Feo F; Pascale RM
Gastroenterology; 2009 Nov; 137(5):1816-26.e1-10. PubMed ID: 19686743
[TBL] [Abstract][Full Text] [Related]
7. High-throughput screening AlphaScreen assay for identification of small-molecule inhibitors of ubiquitin E3 ligase SCFSkp2-Cks1.
Ungermannova D; Lee J; Zhang G; Dallmann HG; McHenry CS; Liu X
J Biomol Screen; 2013 Sep; 18(8):910-20. PubMed ID: 23589337
[TBL] [Abstract][Full Text] [Related]
8. Cdh1-anaphase-promoting complex targets Skp2 for destruction in transforming growth factor beta-induced growth inhibition.
Liu W; Wu G; Li W; Lobur D; Wan Y
Mol Cell Biol; 2007 Apr; 27(8):2967-79. PubMed ID: 17283060
[TBL] [Abstract][Full Text] [Related]
9. Epidermal growth factor upregulates Skp2/Cks1 and p27(kip1) in human extrahepatic cholangiocarcinoma cells.
Kim JY; Kim HJ; Park JH; Park DI; Cho YK; Sohn CI; Jeon WK; Kim BI; Kim DH; Chae SW; Sohn JH
World J Gastroenterol; 2014 Jan; 20(3):755-73. PubMed ID: 24574749
[TBL] [Abstract][Full Text] [Related]
10. Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1.
Rowland RJ; Heath R; Maskell D; Thompson RF; Ranson NA; Blaza JN; Endicott JA; Noble MEM; Salamina M
Sci Rep; 2023 Jul; 13(1):10718. PubMed ID: 37400515
[TBL] [Abstract][Full Text] [Related]
11. Cell adhesion induces p27Kip1-associated cell-cycle arrest through down-regulation of the SCFSkp2 ubiquitin ligase pathway in mantle-cell and other non-Hodgkin B-cell lymphomas.
Lwin T; Hazlehurst LA; Dessureault S; Lai R; Bai W; Sotomayor E; Moscinski LC; Dalton WS; Tao J
Blood; 2007 Sep; 110(5):1631-8. PubMed ID: 17502456
[TBL] [Abstract][Full Text] [Related]
12. Vorinostat enhances protein stability of p27 and p21 through negative regulation of Skp2 and Cks1 in human breast cancer cells.
Uehara N; Yoshizawa K; Tsubura A
Oncol Rep; 2012 Jul; 28(1):105-10. PubMed ID: 22484732
[TBL] [Abstract][Full Text] [Related]
13. Cks1 promotion of S phase entry and proliferation is independent of p27Kip1 suppression.
Hoellein A; Graf S; Bassermann F; Schoeffmann S; Platz U; Hölzlwimmer G; Kröger M; Peschel C; Oostendorp R; Quintanilla-Fend L; Keller U
Mol Cell Biol; 2012 Jul; 32(13):2416-27. PubMed ID: 22508990
[TBL] [Abstract][Full Text] [Related]
14. Transforming growth factor-beta, estrogen, and progesterone converge on the regulation of p27Kip1 in the normal and malignant endometrium.
Lecanda J; Parekh TV; Gama P; Lin K; Liarski V; Uretsky S; Mittal K; Gold LI
Cancer Res; 2007 Feb; 67(3):1007-18. PubMed ID: 17283133
[TBL] [Abstract][Full Text] [Related]
15. Skp2 directs Myc-mediated suppression of p27Kip1 yet has modest effects on Myc-driven lymphomagenesis.
Old JB; Kratzat S; Hoellein A; Graf S; Nilsson JA; Nilsson L; Nakayama KI; Peschel C; Cleveland JL; Keller UB
Mol Cancer Res; 2010 Mar; 8(3):353-62. PubMed ID: 20197382
[TBL] [Abstract][Full Text] [Related]
16. Specific small molecule inhibitors of Skp2-mediated p27 degradation.
Wu L; Grigoryan AV; Li Y; Hao B; Pagano M; Cardozo TJ
Chem Biol; 2012 Dec; 19(12):1515-24. PubMed ID: 23261596
[TBL] [Abstract][Full Text] [Related]
17. Inverse correlation between Skp2 and p27(Kip1) in normal endometrium and endometrial carcinoma.
Miyamoto T; Horiuchi A; Kashima H; Suzuki A; Yamada T; Kurai M; Konishi I; Shiozawa T
Gynecol Endocrinol; 2010 Mar; 26(3):220-9. PubMed ID: 19724954
[TBL] [Abstract][Full Text] [Related]
18. CD28 costimulation mediates transcription of SKP2 and CKS1, the substrate recognition components of SCFSkp2 ubiquitin ligase that leads p27kip1 to degradation.
Appleman LJ; Chernova I; Li L; Boussiotis VA
Cell Cycle; 2006 Sep; 5(18):2123-9. PubMed ID: 16969077
[TBL] [Abstract][Full Text] [Related]
19. Statin-induced depletion of geranylgeranyl pyrophosphate inhibits cell proliferation by a novel pathway of Skp2 degradation.
Vosper J; Masuccio A; Kullmann M; Ploner C; Geley S; Hengst L
Oncotarget; 2015 Feb; 6(5):2889-902. PubMed ID: 25605247
[TBL] [Abstract][Full Text] [Related]
20. p27T187A knockin identifies Skp2/Cks1 pocket inhibitors for advanced prostate cancer.
Zhao H; Lu Z; Bauzon F; Fu H; Cui J; Locker J; Zhu L
Oncogene; 2017 Jan; 36(1):60-70. PubMed ID: 27181203
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
