185 related articles for article (PubMed ID: 26964673)
1. Compound profiling and 3D-QSAR studies of hydrazone derivatives with activity against intracellular Trypanosoma cruzi.
Costa LB; Cardoso MV; de Oliveira Filho GB; de Moraes Gomes PA; Espíndola JW; de Jesus Silva TG; Torres PH; Silva Junior FP; Martin J; de Figueiredo RC; Leite AC
Bioorg Med Chem; 2016 Apr; 24(8):1608-18. PubMed ID: 26964673
[TBL] [Abstract][Full Text] [Related]
2. Synthesis, Biological Evaluation and Molecular Docking of New Benzenesulfonylhydrazone as Potential anti-Trypanosoma cruzi Agents.
Elizondo-Jimenez S; Moreno-Herrera A; Reyes-Olivares R; Dorantes-Gonzalez E; Nogueda-Torres B; Oliveira EAG; Romeiro NC; Lima LM; Palos I; Rivera G
Med Chem; 2017; 13(2):149-158. PubMed ID: 27396731
[TBL] [Abstract][Full Text] [Related]
3. 2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: structural design, synthesis and pharmacological evaluation.
Cardoso MV; de Siqueira LR; da Silva EB; Costa LB; Hernandes MZ; Rabello MM; Ferreira RS; da Cruz LF; Moreira DR; Pereira VR; de Castro MC; Bernhardt PV; Leite AC
Eur J Med Chem; 2014 Oct; 86():48-59. PubMed ID: 25147146
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and antitrypanosomal profile of new functionalized 1,3,4-thiadiazole-2-arylhydrazone derivatives, designed as non-mutagenic megazol analogues.
Carvalho SA; da Silva EF; Santa-Rita RM; de Castro SL; Fraga CA
Bioorg Med Chem Lett; 2004 Dec; 14(24):5967-70. PubMed ID: 15546709
[TBL] [Abstract][Full Text] [Related]
5. Identification of three classes of heteroaromatic compounds with activity against intracellular Trypanosoma cruzi by chemical library screening.
Bettiol E; Samanovic M; Murkin AS; Raper J; Buckner F; Rodriguez A
PLoS Negl Trop Dis; 2009; 3(2):e384. PubMed ID: 19238193
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and 2D-QSAR studies of neolignan-based diaryl-tetrahydrofuran and -furan analogues with remarkable activity against Trypanosoma cruzi and assessment of the trypanothione reductase activity.
Hartmann AP; de Carvalho MR; Bernardes LSC; Moraes MH; de Melo EB; Lopes CD; Steindel M; da Silva JS; Carvalho I
Eur J Med Chem; 2017 Nov; 140():187-199. PubMed ID: 28926763
[TBL] [Abstract][Full Text] [Related]
7. Ligand-based design, synthesis, and experimental evaluation of novel benzofuroxan derivatives as anti-Trypanosoma cruzi agents.
Jorge SD; Palace-Berl F; Mesquita Pasqualoto KF; Ishii M; Ferreira AK; Berra CM; Bosch RV; Maria DA; Tavares LC
Eur J Med Chem; 2013 Jun; 64():200-14. PubMed ID: 23644203
[TBL] [Abstract][Full Text] [Related]
8. Studies toward the structural optimization of new brazilizone-related trypanocidal 1,3,4-thiadiazole-2-arylhydrazone derivatives.
Carvalho SA; Lopes FA; Salomão K; Romeiro NC; Wardell SM; de Castro SL; da Silva EF; Fraga CA
Bioorg Med Chem; 2008 Jan; 16(1):413-21. PubMed ID: 17904851
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis and biological evaluation of hybrid bioisoster derivatives of N-acylhydrazone and furoxan groups with potential and selective anti-Trypanosoma cruzi activity.
Massarico Serafim RA; Gonçalves JE; de Souza FP; de Melo Loureiro AP; Storpirtis S; Krogh R; Andricopulo AD; Dias LC; Ferreira EI
Eur J Med Chem; 2014 Jul; 82():418-25. PubMed ID: 24929292
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and tripanocidal activity of ferrocenyl and benzyl diamines against Trypanosoma brucei and Trypanosoma cruzi.
Velásquez AM; Francisco AI; Kohatsu AA; Silva FA; Rodrigues DF; Teixeira RG; Chiari BG; de Almeida MG; Isaac VL; Vargas MD; Cicarelli RM
Bioorg Med Chem Lett; 2014 Apr; 24(7):1707-10. PubMed ID: 24630563
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and Antitrypanosomal Profile of Novel Hydrazonoyl Derivatives.
Santiago NN; de Alcântara GP; da Costa JS; Carvalho SA; Barbosa JMC; Salomão K; de Castro SL; Pereira HMG; da Silva EF
Med Chem; 2020; 16(4):487-494. PubMed ID: 31309899
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1,2,4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents.
dos Santos Filho JM; Leite AC; de Oliveira BG; Moreira DR; Lima MS; Soares MB; Leite LF
Bioorg Med Chem; 2009 Sep; 17(18):6682-91. PubMed ID: 19683450
[TBL] [Abstract][Full Text] [Related]
13. Desing and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles derivatives which induce apoptotic parasite death.
da Silva EB; Oliveira E Silva DA; Oliveira AR; da Silva Mendes CH; Dos Santos TA; da Silva AC; de Castro MC; Ferreira RS; Moreira DR; Cardoso MV; de Simone CA; Pereira VR; Leite AC
Eur J Med Chem; 2017 Apr; 130():39-50. PubMed ID: 28242550
[TBL] [Abstract][Full Text] [Related]
14. Structural design, synthesis and pharmacological evaluation of 4-thiazolidinones against Trypanosoma cruzi.
de Oliveira Filho GB; de Oliveira Cardoso MV; Espíndola JW; Ferreira LF; de Simone CA; Ferreira RS; Coelho PL; Meira CS; Magalhaes Moreira DR; Soares MB; Lima Leite AC
Bioorg Med Chem; 2015 Dec; 23(23):7478-86. PubMed ID: 26549870
[TBL] [Abstract][Full Text] [Related]
15. Molecular modeling and structure-activity relationships for a series of benzimidazole derivatives as cruzain inhibitors.
Pauli I; Ferreira LG; de Souza ML; Oliva G; Ferreira RS; Dessoy MA; Slafer BW; Dias LC; Andricopulo AD
Future Med Chem; 2017 May; 9(7):641-657. PubMed ID: 28509592
[TBL] [Abstract][Full Text] [Related]
16. Novel coumarins active against Trypanosoma cruzi and toxicity assessment using the animal model Caenorhabditis elegans.
Soares FGN; Göethel G; Kagami LP; das Neves GM; Sauer E; Birriel E; Varela J; Gonçalves IL; Von Poser G; González M; Kawano DF; Paula FR; de Melo EB; Garcia SC; Cerecetto H; Eifler-Lima VL
BMC Pharmacol Toxicol; 2019 Dec; 20(Suppl 1):76. PubMed ID: 31852548
[TBL] [Abstract][Full Text] [Related]
17. Discovery of new potent hits against intracellular Trypanosoma cruzi by QSAR-based virtual screening.
Melo-Filho CC; Braga RC; Muratov EN; Franco CH; Moraes CB; Freitas-Junior LH; Andrade CH
Eur J Med Chem; 2019 Feb; 163():649-659. PubMed ID: 30562700
[TBL] [Abstract][Full Text] [Related]
18. Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death.
Magalhaes Moreira DR; de Oliveira AD; Teixeira de Moraes Gomes PA; de Simone CA; Villela FS; Ferreira RS; da Silva AC; dos Santos TA; Brelaz de Castro MC; Pereira VR; Leite AC
Eur J Med Chem; 2014 Mar; 75():467-78. PubMed ID: 24561675
[TBL] [Abstract][Full Text] [Related]
19. Identification of small-molecule inhibitors of Trypansoma cruzi replication.
Germain AR; Carmody LC; Dockendorff C; Galan-Rodriguez C; Rodriguez A; Johnston S; Bittker JA; MacPherson L; Dandapani S; Palmer M; Schreiber SL; Munoz B
Bioorg Med Chem Lett; 2011 Dec; 21(23):7197-200. PubMed ID: 22018462
[TBL] [Abstract][Full Text] [Related]
20. New potent 5-substituted benzofuroxans as inhibitors of Trypanosoma cruzi growth: quantitative structure-activity relationship studies.
Aguirre G; Boiani L; Boiani M; Cerecetto H; Di Maio R; González M; Porcal W; Denicola A; Piro OE; Castellano EE; Sant'Anna CM; Barreiro EJ
Bioorg Med Chem; 2005 Dec; 13(23):6336-46. PubMed ID: 16202608
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
