450 related articles for article (PubMed ID: 26972920)
1. Rational design, synthesis and biological evaluation of 1,3,4-oxadiazole pyrimidine derivatives as novel pyruvate dehydrogenase complex E1 inhibitors.
He H; Wang W; Zhou Y; Xia Q; Ren Y; Feng J; Peng H; He H; Feng L
Bioorg Med Chem; 2016 Apr; 24(8):1879-88. PubMed ID: 26972920
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis and biological evaluation of novel 2-methylpyrimidine-4-ylamine derivatives as inhibitors of Escherichia coli pyruvate dehydrogenase complex E1.
He J; Feng L; Li J; Tao R; Wang F; Liao X; Sun Q; Long Q; Ren Y; Wan J; He H
Bioorg Med Chem; 2012 Mar; 20(5):1665-70. PubMed ID: 22305934
[TBL] [Abstract][Full Text] [Related]
3. Design and synthesis of highly selective pyruvate dehydrogenase complex E1 inhibitors as bactericides.
Zhou Y; Zhang S; He H; Jiang W; Hou L; Xie D; Cai M; Peng H; Feng L
Bioorg Med Chem; 2018 Jan; 26(1):84-95. PubMed ID: 29170025
[TBL] [Abstract][Full Text] [Related]
4. Design, Synthesis, and Potency of Pyruvate Dehydrogenase Complex E1 Inhibitors against Cyanobacteria.
Zhou Y; Feng J; He H; Hou L; Jiang W; Xie D; Feng L; Cai M; Peng H
Biochemistry; 2017 Dec; 56(49):6491-6502. PubMed ID: 28990770
[TBL] [Abstract][Full Text] [Related]
5. Design and optimization of N-acylhydrazone pyrimidine derivatives as E. coli PDHc E1 inhibitors: Structure-activity relationship analysis, biological evaluation and molecular docking study.
He H; Xia H; Xia Q; Ren Y; He H
Bioorg Med Chem; 2017 Oct; 25(20):5652-5661. PubMed ID: 28866375
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and Activity of 1,2,3-Triazole Aminopyrimidines against Cyanobacteria as PDHc-E1 Competitive Inhibitors.
Zhou Y; Feng J; Feng L; Xie D; Peng H; Cai M; He H
J Agric Food Chem; 2019 Nov; 67(45):12538-12546. PubMed ID: 31638796
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and antifungal activity of 5-iodo-1,4-disubstituted-1,2,3-triazole derivatives as pyruvate dehydrogenase complex E1 inhibitors.
He JB; He HF; Zhao LL; Zhang L; You GY; Feng LL; Wan J; He HW
Bioorg Med Chem; 2015 Apr; 23(7):1395-401. PubMed ID: 25766628
[TBL] [Abstract][Full Text] [Related]
8. The design, synthesis and biological evaluation of novel thiamin diphosphate analog inhibitors against the pyruvate dehydrogenase multienzyme complex E1 from Escherichia coli.
Feng L; He J; He H; Zhao L; Deng L; Zhang L; Zhang L; Ren Y; Wan J; He H
Org Biomol Chem; 2014 Nov; 12(44):8911-8. PubMed ID: 25268578
[TBL] [Abstract][Full Text] [Related]
9. Structure optimization and bioactivity evaluation of ThDP analogs targeting cyanobacterial pyruvate dehydrogenase E1.
Feng J; He H; Zhou Y; Cai M; Peng H; Liu H; Liu L; Feng L; He H
Bioorg Med Chem; 2019 Dec; 27(24):115159. PubMed ID: 31699453
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis and molecular docking of amide and urea derivatives as Escherichia coli PDHc-E1 inhibitors.
He JB; Ren YL; Sun QS; You GY; Zhang L; Zou P; Feng LL; Wan J; He HW
Bioorg Med Chem; 2014 Jun; 22(12):3180-6. PubMed ID: 24800939
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis and biological evaluation of novel inhibitors against cyanobacterial pyruvate dehydrogenase multienzyme complex E1.
Feng J; He H; Zhou Y; Guo X; Liu H; Cai M; Wang F; Feng L; He H
Bioorg Med Chem; 2019 Jun; 27(12):2413-2420. PubMed ID: 30692021
[TBL] [Abstract][Full Text] [Related]
12. Design, Synthesis, and Antifungal Activity of 2,6-Dimethyl-4-aminopyrimidine Hydrazones as PDHc-E1 Inhibitors with a Novel Binding Mode.
Zhou Y; Zhang S; Cai M; Wang K; Feng J; Xie D; Feng L; Peng H; He H
J Agric Food Chem; 2021 Jun; 69(21):5804-5817. PubMed ID: 34008970
[TBL] [Abstract][Full Text] [Related]
13. Discovery of efficient inhibitors against pyruvate dehydrogenase complex component E1 with bactericidal activity using computer aided design.
Zhou Y; Cai M; Zhou H; Hou L; Peng H; He H
Pestic Biochem Physiol; 2021 Aug; 177():104894. PubMed ID: 34301356
[TBL] [Abstract][Full Text] [Related]
14. In silico molecular docking studies of oxadiazole and pyrimidine bearing heterocyclic compounds as potential antimicrobial agents.
Desai NC; Vaghani HV; Jethawa AM; Khedkar VM
Arch Pharm (Weinheim); 2021 Oct; 354(10):e2100134. PubMed ID: 34169569
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and biological evaluation of novel series of aminopyrimidine derivatives as urease inhibitors and antimicrobial agents.
Adsul LK; Bandgar BP; Chavan HV; Jalde SS; Dhakane VD; Shirfule AL
J Enzyme Inhib Med Chem; 2013 Dec; 28(6):1316-23. PubMed ID: 23230954
[TBL] [Abstract][Full Text] [Related]
16. Structure-based rational design of novel hit compounds for pyruvate dehydrogenase multienzyme complex E1 components from Escherichia coli.
Ren Y; He J; Feng L; Liao X; Jin J; Li Y; Cao Y; Wan J; He H
Bioorg Med Chem; 2011 Dec; 19(24):7501-6. PubMed ID: 22078411
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis and molecular modeling of novel N-acylhydrazone derivatives as pyruvate dehydrogenase complex E1 inhibitors.
He JB; Feng LL; Li J; Tao RJ; Ren YL; Wan J; He HW
Bioorg Med Chem; 2014 Jan; 22(1):89-94. PubMed ID: 24359707
[TBL] [Abstract][Full Text] [Related]
18. Rational design, molecular docking and synthesis of novel homopiperazine linked imidazo[1,2-a]pyrimidine derivatives as potent cytotoxic and antimicrobial agents.
Mantipally M; Gangireddy MR; Gundla R; Badavath VN; Mandha SR; Maddipati VC
Bioorg Med Chem Lett; 2019 Aug; 29(16):2248-2253. PubMed ID: 31239178
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and antimicrobical evaluation of a novel class of 1,3,4-thiadiazole: derivatives bearing 1,2,4-triazolo[1,5-a]pyrimidine moiety.
Luo Y; Zhang S; Liu ZJ; Chen W; Fu J; Zeng QF; Zhu HL
Eur J Med Chem; 2013 Jun; 64():54-61. PubMed ID: 23644188
[TBL] [Abstract][Full Text] [Related]
20. Design, synthesis, neuroprotective, antibacterial activities and docking studies of novel thieno[2,3-d]pyrimidine-alkyne Mannich base and oxadiazole hybrids.
Triloknadh S; Venkata Rao C; Nagaraju K; Hari Krishna N; Venkata Ramaiah C; Rajendra W; Trinath D; Suneetha Y
Bioorg Med Chem Lett; 2018 May; 28(9):1663-1669. PubMed ID: 29602681
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
