BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

328 related articles for article (PubMed ID: 26976726)

  • 1. Recent findings and future directions for interpolar mitotic kinesin inhibitors in cancer therapy.
    Myers SM; Collins I
    Future Med Chem; 2016; 8(4):463-89. PubMed ID: 26976726
    [TBL] [Abstract][Full Text] [Related]  

  • 2. KIF15 nanomechanics and kinesin inhibitors, with implications for cancer chemotherapeutics.
    Milic B; Chakraborty A; Han K; Bassik MC; Block SM
    Proc Natl Acad Sci U S A; 2018 May; 115(20):E4613-E4622. PubMed ID: 29703754
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Kolaflavanone, a biflavonoid derived from medicinal plant Garcinia, is an inhibitor of mitotic kinesin Eg5.
    Alrazi IMD; Ogunwa TH; Kolawole AO; Elekofehinti OO; Omotuyi OI; Miyanishi T; Maruta S
    J Biochem; 2021 Dec; 170(5):611-622. PubMed ID: 34264310
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis, and biological evaluation of an allosteric inhibitor of HSET that targets cancer cells with supernumerary centrosomes.
    Watts CA; Richards FM; Bender A; Bond PJ; Korb O; Kern O; Riddick M; Owen P; Myers RM; Raff J; Gergely F; Jodrell DI; Ley SV
    Chem Biol; 2013 Nov; 20(11):1399-410. PubMed ID: 24210220
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of KSP Inhibitors as Anti-cancer Therapeutics: An Update.
    Chamariya R; Suvarna V
    Anticancer Agents Med Chem; 2022; 22(14):2517-2538. PubMed ID: 35043768
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Optical Control of Mitosis with a Photoswitchable Eg5 Inhibitor.
    Impastato AC; Shemet A; Vepřek NA; Saper G; Hess H; Rao L; Gennerich A; Trauner D
    Angew Chem Int Ed Engl; 2022 Feb; 61(9):e202115846. PubMed ID: 34958711
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mitotic kinesins: prospects for antimitotic drug discovery.
    Bergnes G; Brejc K; Belmont L
    Curr Top Med Chem; 2005; 5(2):127-45. PubMed ID: 15853642
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Non-canonical functions of the mitotic kinesin Eg5.
    Liu M; Ran J; Zhou J
    Thorac Cancer; 2018 Aug; 9(8):904-910. PubMed ID: 29927078
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Kinesins and cancer.
    Rath O; Kozielski F
    Nat Rev Cancer; 2012 Jul; 12(8):527-39. PubMed ID: 22825217
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mitotic kinesin inhibitors induce mitotic arrest and cell death in Taxol-resistant and -sensitive cancer cells.
    Marcus AI; Peters U; Thomas SL; Garrett S; Zelnak A; Kapoor TM; Giannakakou P
    J Biol Chem; 2005 Mar; 280(12):11569-77. PubMed ID: 15653676
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Kinesin-5: cross-bridging mechanism to targeted clinical therapy.
    Wojcik EJ; Buckley RS; Richard J; Liu L; Huckaba TM; Kim S
    Gene; 2013 Dec; 531(2):133-49. PubMed ID: 23954229
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of 2-(3-Benzamidopropanamido)thiazole-5-carboxylate Inhibitors of the Kinesin HSET (KIFC1) and the Development of Cellular Target Engagement Probes.
    Saint-Dizier F; Matthews TP; Gregson AM; Prevet H; McHardy T; Colombano G; Saville H; Rowlands M; Ewens C; McAndrew PC; Tomlin K; Guillotin D; Mak GW; Drosopoulos K; Poursaitidis I; Burke R; van Montfort R; Linardopoulos S; Collins I
    J Med Chem; 2023 Feb; 66(4):2622-2645. PubMed ID: 36749938
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Screening for inhibitors of microtubule-associated motor proteins.
    Kozielski F; DeBonis S; Skoufias DA
    Methods Mol Med; 2007; 137():189-207. PubMed ID: 18085231
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Processive Kinesin-14 HSET Exhibits Directional Flexibility Depending on Motor Traffic.
    Reinemann DN; Norris SR; Ohi R; Lang MJ
    Curr Biol; 2018 Jul; 28(14):2356-2362.e5. PubMed ID: 30017484
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of novel scaffolds to inhibit human mitotic kinesin Eg5 targeting the second allosteric binding site using in silico methods.
    Makala H; Ulaganathan V
    J Recept Signal Transduct Res; 2018 Feb; 38(1):12-19. PubMed ID: 29041840
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development and biological evaluation of potent and specific inhibitors of mitotic Kinesin Eg5.
    Gartner M; Sunder-Plassmann N; Seiler J; Utz M; Vernos I; Surrey T; Giannis A
    Chembiochem; 2005 Jul; 6(7):1173-7. PubMed ID: 15912555
    [No Abstract]   [Full Text] [Related]  

  • 17. Kinesin Eg5 Targeting Inhibitors as a New Strategy for Gastric Adenocarcinoma Treatment.
    Marconi GD; Carradori S; Ricci A; Guglielmi P; Cataldi A; Zara S
    Molecules; 2019 Oct; 24(21):. PubMed ID: 31683688
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The crystal structure and biochemical characterization of Kif15: a bifunctional molecular motor involved in bipolar spindle formation and neuronal development.
    Klejnot M; Falnikar A; Ulaganathan V; Cross RA; Baas PW; Kozielski F
    Acta Crystallogr D Biol Crystallogr; 2014 Jan; 70(Pt 1):123-33. PubMed ID: 24419385
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dihydropyrazole and dihydropyrrole structures based design of Kif15 inhibitors as novel therapeutic agents for cancer.
    Sebastian J
    Comput Biol Chem; 2017 Jun; 68():164-174. PubMed ID: 28355588
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Eg5 targeting agents: From new anti-mitotic based inhibitor discovery to cancer therapy and resistance.
    Garcia-Saez I; Skoufias DA
    Biochem Pharmacol; 2021 Feb; 184():114364. PubMed ID: 33310050
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.