BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

315 related articles for article (PubMed ID: 26980189)

  • 1. Fan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction.
    Thongthip S; Bellani M; Gregg SQ; Sridhar S; Conti BA; Chen Y; Seidman MM; Smogorzewska A
    Genes Dev; 2016 Mar; 30(6):645-59. PubMed ID: 26980189
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Karyomegalic interstitial nephritis and DNA damage-induced polyploidy in Fan1 nuclease-defective knock-in mice.
    Lachaud C; Slean M; Marchesi F; Lock C; Odell E; Castor D; Toth R; Rouse J
    Genes Dev; 2016 Mar; 30(6):639-44. PubMed ID: 26980188
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair.
    Smogorzewska A; Desetty R; Saito TT; Schlabach M; Lach FP; Sowa ME; Clark AB; Kunkel TA; Harper JW; Colaiácovo MP; Elledge SJ
    Mol Cell; 2010 Jul; 39(1):36-47. PubMed ID: 20603073
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents.
    Kratz K; Schöpf B; Kaden S; Sendoel A; Eberhard R; Lademann C; Cannavó E; Sartori AA; Hengartner MO; Jiricny J
    Cell; 2010 Jul; 142(1):77-88. PubMed ID: 20603016
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2.
    MacKay C; Déclais AC; Lundin C; Agostinho A; Deans AJ; MacArtney TJ; Hofmann K; Gartner A; West SC; Helleday T; Lilley DM; Rouse J
    Cell; 2010 Jul; 142(1):65-76. PubMed ID: 20603015
    [TBL] [Abstract][Full Text] [Related]  

  • 6. FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair.
    Zhou W; Otto EA; Cluckey A; Airik R; Hurd TW; Chaki M; Diaz K; Lach FP; Bennett GR; Gee HY; Ghosh AK; Natarajan S; Thongthip S; Veturi U; Allen SJ; Janssen S; Ramaswami G; Dixon J; Burkhalter F; Spoendlin M; Moch H; Mihatsch MJ; Verine J; Reade R; Soliman H; Godin M; Kiss D; Monga G; Mazzucco G; Amann K; Artunc F; Newland RC; Wiech T; Zschiedrich S; Huber TB; Friedl A; Slaats GG; Joles JA; Goldschmeding R; Washburn J; Giles RH; Levy S; Smogorzewska A; Hildebrandt F
    Nat Genet; 2012 Jul; 44(8):910-5. PubMed ID: 22772369
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A FANCD2/FANCI-Associated Nuclease 1-Knockout Model Develops Karyomegalic Interstitial Nephritis.
    Airik R; Schueler M; Airik M; Cho J; Porath JD; Mukherjee E; Sims-Lucas S; Hildebrandt F
    J Am Soc Nephrol; 2016 Dec; 27(12):3552-3559. PubMed ID: 27026368
    [TBL] [Abstract][Full Text] [Related]  

  • 8. FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2.
    Porro A; Berti M; Pizzolato J; Bologna S; Kaden S; Saxer A; Ma Y; Nagasawa K; Sartori AA; Jiricny J
    Nat Commun; 2017 Oct; 8(1):1073. PubMed ID: 29051491
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural and functional relationships of FAN1.
    Jin H; Cho Y
    DNA Repair (Amst); 2017 Aug; 56():135-143. PubMed ID: 28623094
    [TBL] [Abstract][Full Text] [Related]  

  • 10. KIAA1018/FAN1 nuclease protects cells against genomic instability induced by interstrand cross-linking agents.
    Yoshikiyo K; Kratz K; Hirota K; Nishihara K; Takata M; Kurumizaka H; Horimoto S; Takeda S; Jiricny J
    Proc Natl Acad Sci U S A; 2010 Dec; 107(50):21553-7. PubMed ID: 21115814
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway.
    Yamamoto KN; Kobayashi S; Tsuda M; Kurumizaka H; Takata M; Kono K; Jiricny J; Takeda S; Hirota K
    Proc Natl Acad Sci U S A; 2011 Apr; 108(16):6492-6. PubMed ID: 21464321
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Persistent DNA damage underlies tubular cell polyploidization and progression to chronic kidney disease in kidneys deficient in the DNA repair protein FAN1.
    Airik M; Phua YL; Huynh AB; McCourt BT; Rush BM; Tan RJ; Vockley J; Murray SL; Dorman A; Conlon PJ; Airik R
    Kidney Int; 2022 Nov; 102(5):1042-1056. PubMed ID: 35931300
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1.
    Wang R; Persky NS; Yoo B; Ouerfelli O; Smogorzewska A; Elledge SJ; Pavletich NP
    Science; 2014 Nov; 346(6213):1127-30. PubMed ID: 25430771
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Crystal structure of a Fanconi anemia-associated nuclease homolog bound to 5' flap DNA: basis of interstrand cross-link repair by FAN1.
    Gwon GH; Kim Y; Liu Y; Watson AT; Jo A; Etheridge TJ; Yuan F; Zhang Y; Kim Y; Carr AM; Cho Y
    Genes Dev; 2014 Oct; 28(20):2276-90. PubMed ID: 25319828
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Orchestrating the nucleases involved in DNA interstrand cross-link (ICL) repair.
    Sengerová B; Wang AT; McHugh PJ
    Cell Cycle; 2011 Dec; 10(23):3999-4008. PubMed ID: 22101340
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The conserved Fanconi anemia nuclease Fan1 and the SUMO E3 ligase Pli1 act in two novel Pso2-independent pathways of DNA interstrand crosslink repair in yeast.
    Fontebasso Y; Etheridge TJ; Oliver AW; Murray JM; Carr AM
    DNA Repair (Amst); 2013 Dec; 12(12):1011-23. PubMed ID: 24192486
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ubiquitinated Fancd2 recruits Fan1 to stalled replication forks to prevent genome instability.
    Lachaud C; Moreno A; Marchesi F; Toth R; Blow JJ; Rouse J
    Science; 2016 Feb; 351(6275):846-9. PubMed ID: 26797144
    [TBL] [Abstract][Full Text] [Related]  

  • 18. FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair.
    Liu T; Ghosal G; Yuan J; Chen J; Huang J
    Science; 2010 Aug; 329(5992):693-6. PubMed ID: 20671156
    [TBL] [Abstract][Full Text] [Related]  

  • 19. FANCD2-controlled chromatin access of the Fanconi-associated nuclease FAN1 is crucial for the recovery of stalled replication forks.
    Chaudhury I; Stroik DR; Sobeck A
    Mol Cell Biol; 2014 Nov; 34(21):3939-54. PubMed ID: 25135477
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanism and regulation of incisions during DNA interstrand cross-link repair.
    Zhang J; Walter JC
    DNA Repair (Amst); 2014 Jul; 19():135-42. PubMed ID: 24768452
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.