BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 26992888)

  • 1. Rapamycin prevents, but does not reverse, aberrant migration in Pten knockout neurons.
    Getz SA; DeSpenza T; Li M; Luikart BW
    Neurobiol Dis; 2016 Sep; 93():12-20. PubMed ID: 26992888
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PTEN Regulates Dendritic Arborization by Decreasing Microtubule Polymerization Rate.
    Getz SA; Tariq K; Marchand DH; Dickson CR; Howe Vi JR; Skelton PD; Wang W; Li M; Barry JM; Hong J; Luikart BW
    J Neurosci; 2022 Mar; 42(10):1945-1957. PubMed ID: 35101965
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice.
    Zhou J; Blundell J; Ogawa S; Kwon CH; Zhang W; Sinton C; Powell CM; Parada LF
    J Neurosci; 2009 Feb; 29(6):1773-83. PubMed ID: 19211884
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Rapamycin improves social and stereotypic behavior abnormalities induced by pre-mitotic neuronal subset specific Pten deletion.
    Narvaiz DA; Nolan SO; Smith GD; Holley AJ; Reynolds CD; Blandin KJ; Nguyen PH; Tran DLK; Lugo JN
    Genes Brain Behav; 2023 Aug; 22(4):e12854. PubMed ID: 37376966
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Disruption of mTORC1 rescues neuronal overgrowth and synapse function dysregulated by Pten loss.
    Tariq K; Cullen E; Getz SA; Conching AKS; Goyette AR; Prina ML; Wang W; Li M; Weston MC; Luikart BW
    Cell Rep; 2022 Nov; 41(5):111574. PubMed ID: 36323257
    [TBL] [Abstract][Full Text] [Related]  

  • 6. mTOR inhibition suppresses established epilepsy in a mouse model of cortical dysplasia.
    Nguyen LH; Brewster AL; Clark ME; Regnier-Golanov A; Sunnen CN; Patil VV; D'Arcangelo G; Anderson AE
    Epilepsia; 2015 Apr; 56(4):636-46. PubMed ID: 25752454
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Impact of mTOR hyperactive neurons on the morphology and physiology of adjacent neurons: Do PTEN KO cells make bad neighbors?
    LaSarge CL; Pun RYK; Gu Z; Santos VR; Danzer SC
    Exp Neurol; 2019 Nov; 321():113029. PubMed ID: 31377403
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential roles for Akt and mTORC1 in the hypertrophy of Pten mutant neurons, a cellular model of brain overgrowth disorders.
    Nikolaeva I; Kazdoba TM; Crowell B; D'Arcangelo G
    Neuroscience; 2017 Jun; 354():196-207. PubMed ID: 28457820
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of mammalian target of rapamycin with rapamycin reverses hypertrophic cardiomyopathy in mice with cardiomyocyte-specific knockout of PTEN.
    Xu X; Roe ND; Weiser-Evans MC; Ren J
    Hypertension; 2014 Apr; 63(4):729-39. PubMed ID: 24446058
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nuclear Excluded Autism-Associated Phosphatase and Tensin Homolog Mutations Dysregulate Neuronal Growth.
    Fricano-Kugler CJ; Getz SA; Williams MR; Zurawel AA; DeSpenza T; Frazel PW; Li M; O'Malley AJ; Moen EL; Luikart BW
    Biol Psychiatry; 2018 Aug; 84(4):265-277. PubMed ID: 29373119
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synergistic hyperactivation of both mTORC1 and mTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and cortical organoids.
    Dhaliwal NK; Weng OY; Dong X; Bhattacharya A; Ahmed M; Nishimura H; Choi WWY; Aggarwal A; Luikart BW; Shu Q; Li X; Wilson MD; Moffat J; Wang LY; Muffat J; Li Y
    Cell Rep; 2024 May; 43(5):114173. PubMed ID: 38700984
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Balancing Proliferation and Connectivity in PTEN-associated Autism Spectrum Disorder.
    Tilot AK; Frazier TW; Eng C
    Neurotherapeutics; 2015 Jul; 12(3):609-19. PubMed ID: 25916396
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hyperactive mTOR signals in the proopiomelanocortin-expressing hippocampal neurons cause age-dependent epilepsy and premature death in mice.
    Matsushita Y; Sakai Y; Shimmura M; Shigeto H; Nishio M; Akamine S; Sanefuji M; Ishizaki Y; Torisu H; Nakabeppu Y; Suzuki A; Takada H; Hara T
    Sci Rep; 2016 Mar; 6():22991. PubMed ID: 26961412
    [TBL] [Abstract][Full Text] [Related]  

  • 14. mTOR-dependent alterations of Kv1.1 subunit expression in the neuronal subset-specific Pten knockout mouse model of cortical dysplasia with epilepsy.
    Nguyen LH; Anderson AE
    Sci Rep; 2018 Feb; 8(1):3568. PubMed ID: 29476105
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Development and characterization of NEX- Pten, a novel forebrain excitatory neuron-specific knockout mouse.
    Kazdoba TM; Sunnen CN; Crowell B; Lee GH; Anderson AE; D'Arcangelo G
    Dev Neurosci; 2012; 34(2-3):198-209. PubMed ID: 22572802
    [TBL] [Abstract][Full Text] [Related]  

  • 16. mTORC2 Inhibition Improves Morphological Effects of PTEN Loss, But Does Not Correct Synaptic Dysfunction or Prevent Seizures.
    Cullen ER; Tariq K; Shore AN; Luikart BW; Weston MC
    J Neurosci; 2023 Feb; 43(5):827-845. PubMed ID: 36526374
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neurovascular Development in
    Dusing M; LaSarge CL; White A; Jerow LG; Gross C; Danzer SC
    eNeuro; 2023 Feb; 10(2):. PubMed ID: 36759189
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism.
    Takeuchi K; Gertner MJ; Zhou J; Parada LF; Bennett MV; Zukin RS
    Proc Natl Acad Sci U S A; 2013 Mar; 110(12):4738-43. PubMed ID: 23487788
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Autism-relevant behaviors are minimally impacted by conditional deletion of Pten in oxytocinergic neurons.
    Clipperton-Allen AE; Chen Y; Page DT
    Autism Res; 2016 Dec; 9(12):1248-1262. PubMed ID: 27220363
    [TBL] [Abstract][Full Text] [Related]  

  • 20. S6k1 is not required for Pten-deficient neuronal hypertrophy.
    Chalhoub N; Kozma SC; Baker SJ
    Brain Res; 2006 Jul; 1100(1):32-41. PubMed ID: 16777079
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.