941 related articles for article (PubMed ID: 26994748)
1. Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes.
Kandel BA; Thomas M; Winter S; Damm G; Seehofer D; Burk O; Schwab M; Zanger UM
Biochim Biophys Acta; 2016 Sep; 1859(9):1218-1227. PubMed ID: 26994748
[TBL] [Abstract][Full Text] [Related]
2. RNA-Seq reveals common and unique PXR- and CAR-target gene signatures in the mouse liver transcriptome.
Cui JY; Klaassen CD
Biochim Biophys Acta; 2016 Sep; 1859(9):1198-1217. PubMed ID: 27113289
[TBL] [Abstract][Full Text] [Related]
3. Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice.
Shizu R; Benoki S; Numakura Y; Kodama S; Miyata M; Yamazoe Y; Yoshinari K
PLoS One; 2013; 8(4):e61802. PubMed ID: 23626729
[TBL] [Abstract][Full Text] [Related]
4. Differences in Gene Regulation by Dual Ligands of Nuclear Receptors Constitutive Androstane Receptor (CAR) and Pregnane X Receptor (PXR) in HepG2 Cells Stably Expressing CAR/PXR.
Kanno Y; Tanuma N; Yazawa S; Zhao S; Inaba M; Nakamura S; Nemoto K; Inouye Y
Drug Metab Dispos; 2016 Aug; 44(8):1158-63. PubMed ID: 27197997
[TBL] [Abstract][Full Text] [Related]
5. Bioinformatic analysis of microRNA networks following the activation of the constitutive androstane receptor (CAR) in mouse liver.
Hao R; Su S; Wan Y; Shen F; Niu B; Coslo DM; Albert I; Han X; Omiecinski CJ
Biochim Biophys Acta; 2016 Sep; 1859(9):1228-1237. PubMed ID: 27080131
[TBL] [Abstract][Full Text] [Related]
6. Transcriptional activation of PPARalpha by phenobarbital in the absence of CAR and PXR.
Tamasi V; Juvan P; Beer M; Rozman D; Meyer UA
Mol Pharm; 2009; 6(5):1573-81. PubMed ID: 19708687
[TBL] [Abstract][Full Text] [Related]
7. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
[TBL] [Abstract][Full Text] [Related]
8. Activating and Inhibitory Functions of WNT/β-Catenin in the Induction of Cytochromes P450 by Nuclear Receptors in HepaRG Cells.
Thomas M; Bayha C; Vetter S; Hofmann U; Schwarz M; Zanger UM; Braeuning A
Mol Pharmacol; 2015 Jun; 87(6):1013-20. PubMed ID: 25824487
[TBL] [Abstract][Full Text] [Related]
9. Nuclear receptors and nonalcoholic fatty liver disease.
Cave MC; Clair HB; Hardesty JE; Falkner KC; Feng W; Clark BJ; Sidey J; Shi H; Aqel BA; McClain CJ; Prough RA
Biochim Biophys Acta; 2016 Sep; 1859(9):1083-1099. PubMed ID: 26962021
[TBL] [Abstract][Full Text] [Related]
10. Editor's Highlight: Neonatal Activation of the Xenobiotic-Sensors PXR and CAR Results in Acute and Persistent Down-regulation of PPARα-Signaling in Mouse Liver.
Li CY; Cheng SL; Bammler TK; Cui JY
Toxicol Sci; 2016 Oct; 153(2):282-302. PubMed ID: 27413110
[TBL] [Abstract][Full Text] [Related]
11. Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification.
Maglich JM; Stoltz CM; Goodwin B; Hawkins-Brown D; Moore JT; Kliewer SA
Mol Pharmacol; 2002 Sep; 62(3):638-46. PubMed ID: 12181440
[TBL] [Abstract][Full Text] [Related]
12. Modulation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation by ursolic acid (UA) attenuates rifampin-isoniazid cytotoxicity.
Chang HY; Chen CJ; Ma WC; Cheng WK; Lin YN; Lee YR; Chen JJ; Lim YP
Phytomedicine; 2017 Dec; 36():37-49. PubMed ID: 29157826
[TBL] [Abstract][Full Text] [Related]
13. PXR- and CAR-mediated herbal effect on human diseases.
Xu C; Huang M; Bi H
Biochim Biophys Acta; 2016 Sep; 1859(9):1121-1129. PubMed ID: 26906544
[TBL] [Abstract][Full Text] [Related]
14. Mechanisms of xenobiotic receptor activation: Direct vs. indirect.
Mackowiak B; Wang H
Biochim Biophys Acta; 2016 Sep; 1859(9):1130-1140. PubMed ID: 26877237
[TBL] [Abstract][Full Text] [Related]
15. Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor.
Duret C; Daujat-Chavanieu M; Pascussi JM; Pichard-Garcia L; Balaguer P; Fabre JM; Vilarem MJ; Maurel P; Gerbal-Chaloin S
Mol Pharmacol; 2006 Jul; 70(1):329-39. PubMed ID: 16608920
[TBL] [Abstract][Full Text] [Related]
16. Transcriptional regulation of the PXR gene: identification and characterization of a functional peroxisome proliferator-activated receptor alpha binding site within the proximal promoter of PXR.
Aouabdi S; Gibson G; Plant N
Drug Metab Dispos; 2006 Jan; 34(1):138-44. PubMed ID: 16243957
[TBL] [Abstract][Full Text] [Related]
17. Establishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human Hepatocytes.
Moscovitz JE; Kalgutkar AS; Nulick K; Johnson N; Lin Z; Goosen TC; Weng Y
J Pharmacol Exp Ther; 2018 May; 365(2):262-271. PubMed ID: 29440451
[TBL] [Abstract][Full Text] [Related]
18. Coordinated regulation of hepatic phase I and II drug-metabolizing genes and transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-null mice.
Aleksunes LM; Klaassen CD
Drug Metab Dispos; 2012 Jul; 40(7):1366-79. PubMed ID: 22496397
[TBL] [Abstract][Full Text] [Related]
19. Regulation of the human CYP2B6 gene by the nuclear pregnane X receptor.
Goodwin B; Moore LB; Stoltz CM; McKee DD; Kliewer SA
Mol Pharmacol; 2001 Sep; 60(3):427-31. PubMed ID: 11502872
[TBL] [Abstract][Full Text] [Related]
20. Small-molecule modulators of PXR and CAR.
Chai SC; Cherian MT; Wang YM; Chen T
Biochim Biophys Acta; 2016 Sep; 1859(9):1141-1154. PubMed ID: 26921498
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
