942 related articles for article (PubMed ID: 26994748)
21. Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor.
Faucette SR; Sueyoshi T; Smith CM; Negishi M; Lecluyse EL; Wang H
J Pharmacol Exp Ther; 2006 Jun; 317(3):1200-9. PubMed ID: 16513849
[TBL] [Abstract][Full Text] [Related]
22. Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes.
Sahi J; Shord SS; Lindley C; Ferguson S; LeCluyse EL
J Biochem Mol Toxicol; 2009; 23(1):43-58. PubMed ID: 19202563
[TBL] [Abstract][Full Text] [Related]
23. Characterization of ligand-dependent activation of bovine and pig constitutive androstane (CAR) and pregnane X receptors (PXR) with interspecies comparisons.
Küblbeck J; Zancanella V; Prantner V; Molnár F; Squires EJ; Dacasto M; Honkakoski P; Giantin M
Xenobiotica; 2016; 46(3):200-10. PubMed ID: 26153444
[TBL] [Abstract][Full Text] [Related]
24. The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes.
Song X; Xie M; Zhang H; Li Y; Sachdeva K; Yan B
Drug Metab Dispos; 2004 Jan; 32(1):35-42. PubMed ID: 14709618
[TBL] [Abstract][Full Text] [Related]
25. Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes.
Maglich JM; Parks DJ; Moore LB; Collins JL; Goodwin B; Billin AN; Stoltz CA; Kliewer SA; Lambert MH; Willson TM; Moore JT
J Biol Chem; 2003 May; 278(19):17277-83. PubMed ID: 12611900
[TBL] [Abstract][Full Text] [Related]
26. Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR.
Tolson AH; Wang H
Adv Drug Deliv Rev; 2010 Oct; 62(13):1238-49. PubMed ID: 20727377
[TBL] [Abstract][Full Text] [Related]
27. A SUMO-acetyl switch in PXR biology.
Cui W; Sun M; Zhang S; Shen X; Galeva N; Williams TD; Staudinger JL
Biochim Biophys Acta; 2016 Sep; 1859(9):1170-1182. PubMed ID: 26883953
[TBL] [Abstract][Full Text] [Related]
28. Regulation of Drug Metabolism by the Interplay of Inflammatory Signaling, Steatosis, and Xeno-Sensing Receptors in HepaRG Cells.
Tanner N; Kubik L; Luckert C; Thomas M; Hofmann U; Zanger UM; Böhmert L; Lampen A; Braeuning A
Drug Metab Dispos; 2018 Apr; 46(4):326-335. PubMed ID: 29330220
[TBL] [Abstract][Full Text] [Related]
29. The role of hepatocyte RXR alpha in xenobiotic-sensing nuclear receptor-mediated pathways.
Cai Y; Konishi T; Han G; Campwala KH; French SW; Wan YJ
Eur J Pharm Sci; 2002 Feb; 15(1):89-96. PubMed ID: 11803135
[TBL] [Abstract][Full Text] [Related]
30. The nuclear receptors pregnane X receptor and constitutive androstane receptor contribute to the impact of fipronil on hepatic gene expression linked to thyroid hormone metabolism.
Roques BB; Leghait J; Lacroix MZ; Lasserre F; Pineau T; Viguié C; Martin PG
Biochem Pharmacol; 2013 Oct; 86(7):997-1039. PubMed ID: 23962444
[TBL] [Abstract][Full Text] [Related]
31. Direct transcriptional regulation of human hepatic cytochrome P450 3A4 (CYP3A4) by peroxisome proliferator-activated receptor alpha (PPARα).
Thomas M; Burk O; Klumpp B; Kandel BA; Damm G; Weiss TS; Klein K; Schwab M; Zanger UM
Mol Pharmacol; 2013 Mar; 83(3):709-18. PubMed ID: 23295386
[TBL] [Abstract][Full Text] [Related]
32. The human primary hepatocyte transcriptome reveals novel insights into atorvastatin and rosuvastatin action.
Hafner M; Juvan P; Rezen T; Monostory K; Pascussi JM; Rozman D
Pharmacogenet Genomics; 2011 Nov; 21(11):741-50. PubMed ID: 21869732
[TBL] [Abstract][Full Text] [Related]
33. Regulation of mouse organic anion-transporting polypeptides (Oatps) in liver by prototypical microsomal enzyme inducers that activate distinct transcription factor pathways.
Cheng X; Maher J; Dieter MZ; Klaassen CD
Drug Metab Dispos; 2005 Sep; 33(9):1276-82. PubMed ID: 15919853
[TBL] [Abstract][Full Text] [Related]
34. Effects of nuclear receptor transactivation on boar taint metabolism and gene expression in porcine hepatocytes.
Gray MA; Squires EJ
J Steroid Biochem Mol Biol; 2013 Jan; 133():110-9. PubMed ID: 23032374
[TBL] [Abstract][Full Text] [Related]
35. A human immunodeficiency virus protease inhibitor is a novel functional inhibitor of human pregnane X receptor.
Healan-Greenberg C; Waring JF; Kempf DJ; Blomme EA; Tirona RG; Kim RB
Drug Metab Dispos; 2008 Mar; 36(3):500-7. PubMed ID: 18096673
[TBL] [Abstract][Full Text] [Related]
36. Genome-wide analysis of human constitutive androstane receptor (CAR) transcriptome in wild-type and CAR-knockout HepaRG cells.
Li D; Mackowiak B; Brayman TG; Mitchell M; Zhang L; Huang SM; Wang H
Biochem Pharmacol; 2015 Nov; 98(1):190-202. PubMed ID: 26275810
[TBL] [Abstract][Full Text] [Related]
37. Perfluorocarboxylic acids induce cytochrome P450 enzymes in mouse liver through activation of PPAR-alpha and CAR transcription factors.
Cheng X; Klaassen CD
Toxicol Sci; 2008 Nov; 106(1):29-36. PubMed ID: 18648086
[TBL] [Abstract][Full Text] [Related]
38. Role of constitutive androstane receptor in Toll-like receptor-mediated regulation of gene expression of hepatic drug-metabolizing enzymes and transporters.
Shah P; Guo T; Moore DD; Ghose R
Drug Metab Dispos; 2014 Jan; 42(1):172-81. PubMed ID: 24194512
[TBL] [Abstract][Full Text] [Related]
39. Effects of atorvastatin metabolites on induction of drug-metabolizing enzymes and membrane transporters through human pregnane X receptor.
Hoffart E; Ghebreghiorghis L; Nussler AK; Thasler WE; Weiss TS; Schwab M; Burk O
Br J Pharmacol; 2012 Mar; 165(5):1595-608. PubMed ID: 21913896
[TBL] [Abstract][Full Text] [Related]
40. Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4alpha.
Ferguson SS; Chen Y; LeCluyse EL; Negishi M; Goldstein JA
Mol Pharmacol; 2005 Sep; 68(3):747-57. PubMed ID: 15933212
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
