These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 26999093)

  • 1. Binding Mode and Selectivity of Steroids towards Glucose-6-phosphate Dehydrogenase from the Pathogen Trypanosoma cruzi.
    Ortiz C; Moraca F; Medeiros A; Botta M; Hamilton N; Comini MA
    Molecules; 2016 Mar; 21(3):368. PubMed ID: 26999093
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Glucose 6-Phosphate Dehydrogenase from Trypanosomes: Selectivity for Steroids and Chemical Validation in Bloodstream
    Ortíz C; Moraca F; Laverriere M; Jordan A; Hamilton N; Comini MA
    Molecules; 2021 Jan; 26(2):. PubMed ID: 33445584
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 16-bromoepiandrosterone, an activator of the mammalian immune system, inhibits glucose 6-phosphate dehydrogenase from Trypanosoma cruzi and is toxic to these parasites grown in culture.
    Cordeiro AT; Thiemann OH
    Bioorg Med Chem; 2010 Jul; 18(13):4762-8. PubMed ID: 20570159
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glucose-6-phosphate dehydrogenase is the target for the trypanocidal action of human steroids.
    Gupta S; Cordeiro AT; Michels PA
    Mol Biochem Parasitol; 2011 Apr; 176(2):112-5. PubMed ID: 21185333
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of new uncompetitive inhibitors of glucose-6-phosphate dehydrogenase.
    Mercaldi GF; Ranzani AT; Cordeiro AT
    J Biomol Screen; 2014 Dec; 19(10):1362-71. PubMed ID: 25121555
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glucose-6-Phosphate Dehydrogenase from the Human Pathogen Trypanosoma cruzi Evolved Unique Structural Features to Support Efficient Product Formation.
    Ortíz C; Botti H; Buschiazzo A; Comini MA
    J Mol Biol; 2019 May; 431(11):2143-2162. PubMed ID: 30930048
    [TBL] [Abstract][Full Text] [Related]  

  • 7. NADPH Producing Enzymes as Promising Drug Targets for Chagas Disease.
    Cordeiro AT
    Curr Med Chem; 2019; 26(36):6564-6571. PubMed ID: 30306853
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The structure of a Trypanosoma cruzi glucose-6-phosphate dehydrogenase reveals differences from the mammalian enzyme.
    Mercaldi GF; Dawson A; Hunter WN; Cordeiro AT
    FEBS Lett; 2016 Aug; 590(16):2776-86. PubMed ID: 27391210
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of Trypanosoma brucei glucose-6-phosphate dehydrogenase by human steroids and their effects on the viability of cultured parasites.
    Cordeiro AT; Thiemann OH; Michels PA
    Bioorg Med Chem; 2009 Mar; 17(6):2483-9. PubMed ID: 19231202
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In silico identification of inhibitors of ribose 5-phosphate isomerase from Trypanosoma cruzi using ligand and structure based approaches.
    de V C Sinatti V; R Baptista LP; Alves-Ferreira M; Dardenne L; Hermínio Martins da Silva J; Guimarães AC
    J Mol Graph Model; 2017 Oct; 77():168-180. PubMed ID: 28865321
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The glucose-6-phosphate dehydrogenase from Trypanosoma cruzi: its role in the defense of the parasite against oxidative stress.
    Igoillo-Esteve M; Cazzulo JJ
    Mol Biochem Parasitol; 2006 Oct; 149(2):170-81. PubMed ID: 16828178
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Recent developments in trans-sialidase inhibitors of Trypanosoma cruzi.
    Kashif M; Moreno-Herrera A; Lara-Ramirez EE; Ramírez-Moreno E; Bocanegra-García V; Ashfaq M; Rivera G
    J Drug Target; 2017 Jul; 25(6):485-498. PubMed ID: 28140698
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Development of Selective Steroid Inhibitors for the Glucose-6-phosphate Dehydrogenase from
    Fredo Naciuk F; do Nascimento Faria J; Gonçalves Eufrásio A; Torres Cordeiro A; Bruder M
    ACS Med Chem Lett; 2020 Jun; 11(6):1250-1256. PubMed ID: 32551008
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis, and evaluation of substrate - analogue inhibitors of Trypanosoma cruzi ribose 5-phosphate isomerase type B.
    Gonzalez SN; Mills JJ; Maugeri D; Olaya C; Laguera BL; Enders JR; Sherman J; Rodriguez A; Pierce JG; Cazzulo JJ; D'Antonio EL
    Bioorg Med Chem Lett; 2021 Jan; 32():127723. PubMed ID: 33249135
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The synthesis and kinetic evaluation of aryl α-aminophosphonates as novel inhibitors of T. cruzi trans-sialidase.
    Chen Z; Marcé P; Resende R; Alzari PM; Frasch AC; van den Elsen JMH; Crennell SJ; Watts AG
    Eur J Med Chem; 2018 Oct; 158():25-33. PubMed ID: 30199703
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, molecular docking and biological evaluation of novel phthaloyl derivatives of 3-amino-3-aryl propionic acids as inhibitors of Trypanosoma cruzi trans-sialidase.
    Kashif M; Chacón-Vargas KF; López-Cedillo JC; Nogueda-Torres B; Paz-González AD; Ramírez-Moreno E; Agusti R; Uhrig ML; Reyes-Arellano A; Peralta-Cruz J; Ashfaq M; Rivera G
    Eur J Med Chem; 2018 Aug; 156():252-268. PubMed ID: 30006170
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Anti-Trypanosoma cruzi activity of nicotinamide.
    Soares MB; Silva CV; Bastos TM; Guimarães ET; Figueira CP; Smirlis D; Azevedo WF
    Acta Trop; 2012 May; 122(2):224-9. PubMed ID: 22281243
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel N,N-di-alkylnaphthoimidazolium derivative of β-lapachone impaired Trypanosoma cruzi mitochondrial electron transport system.
    Bombaça ACS; Silva LA; Chaves OA; da Silva LS; Barbosa JMC; da Silva AM; Ferreira ABB; Menna-Barreto RFS
    Biomed Pharmacother; 2021 Mar; 135():111186. PubMed ID: 33395606
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Efficient identification of inhibitors targeting the closed active site conformation of the HPRT from Trypanosoma cruzi.
    Freymann DM; Wenck MA; Engel JC; Feng J; Focia PJ; Eakin AE; Craig SP
    Chem Biol; 2000 Dec; 7(12):957-68. PubMed ID: 11137818
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluation of proline analogs as trypanocidal agents through the inhibition of a Trypanosoma cruzi proline transporter.
    Sayé M; Fargnoli L; Reigada C; Labadie GR; Pereira CA
    Biochim Biophys Acta Gen Subj; 2017 Nov; 1861(11 Pt A):2913-2921. PubMed ID: 28844978
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.