1136 related articles for article (PubMed ID: 27002158)
1. Enhancing NAD+ Salvage Pathway Reverts the Toxicity of Primary Astrocytes Expressing Amyotrophic Lateral Sclerosis-linked Mutant Superoxide Dismutase 1 (SOD1).
Harlan BA; Pehar M; Sharma DR; Beeson G; Beeson CC; Vargas MR
J Biol Chem; 2016 May; 291(20):10836-46. PubMed ID: 27002158
[TBL] [Abstract][Full Text] [Related]
2. Evaluation of the NAD
Harlan BA; Killoy KM; Pehar M; Liu L; Auwerx J; Vargas MR
Exp Neurol; 2020 May; 327():113219. PubMed ID: 32014438
[TBL] [Abstract][Full Text] [Related]
3. Mitochondria-targeted catalase reverts the neurotoxicity of hSOD1G⁹³A astrocytes without extending the survival of ALS-linked mutant hSOD1 mice.
Pehar M; Beeson G; Beeson CC; Johnson JA; Vargas MR
PLoS One; 2014; 9(7):e103438. PubMed ID: 25054289
[TBL] [Abstract][Full Text] [Related]
4. Enhanced SIRT6 activity abrogates the neurotoxic phenotype of astrocytes expressing ALS-linked mutant SOD1.
Harlan BA; Pehar M; Killoy KM; Vargas MR
FASEB J; 2019 Jun; 33(6):7084-7091. PubMed ID: 30841754
[TBL] [Abstract][Full Text] [Related]
5. Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1
Zhou Q; Zhu L; Qiu W; Liu Y; Yang F; Chen W; Xu R
Int J Biol Sci; 2020; 16(2):284-297. PubMed ID: 31929756
[TBL] [Abstract][Full Text] [Related]
6. Mutant copper-zinc superoxide dismutase (SOD1) induces protein secretion pathway alterations and exosome release in astrocytes: implications for disease spreading and motor neuron pathology in amyotrophic lateral sclerosis.
Basso M; Pozzi S; Tortarolo M; Fiordaliso F; Bisighini C; Pasetto L; Spaltro G; Lidonnici D; Gensano F; Battaglia E; Bendotti C; Bonetto V
J Biol Chem; 2013 May; 288(22):15699-711. PubMed ID: 23592792
[TBL] [Abstract][Full Text] [Related]
7. Modulation of astrocytic mitochondrial function by dichloroacetate improves survival and motor performance in inherited amyotrophic lateral sclerosis.
Miquel E; Cassina A; Martínez-Palma L; Bolatto C; Trías E; Gandelman M; Radi R; Barbeito L; Cassina P
PLoS One; 2012; 7(4):e34776. PubMed ID: 22509356
[TBL] [Abstract][Full Text] [Related]
8. Knocking down metabotropic glutamate receptor 1 improves survival and disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
Milanese M; Giribaldi F; Melone M; Bonifacino T; Musante I; Carminati E; Rossi PI; Vergani L; Voci A; Conti F; Puliti A; Bonanno G
Neurobiol Dis; 2014 Apr; 64():48-59. PubMed ID: 24361555
[TBL] [Abstract][Full Text] [Related]
9. NR1D1 downregulation in astrocytes induces a phenotype that is detrimental to cocultured motor neurons.
Killoy KM; Harlan BA; Pehar M; Vargas MR
FASEB J; 2022 Apr; 36(4):e22262. PubMed ID: 35319791
[TBL] [Abstract][Full Text] [Related]
10. NLRP3 inflammasome is expressed by astrocytes in the SOD1 mouse model of ALS and in human sporadic ALS patients.
Johann S; Heitzer M; Kanagaratnam M; Goswami A; Rizo T; Weis J; Troost D; Beyer C
Glia; 2015 Dec; 63(12):2260-73. PubMed ID: 26200799
[TBL] [Abstract][Full Text] [Related]
11. Urate mitigates oxidative stress and motor neuron toxicity of astrocytes derived from ALS-linked SOD1
Bakshi R; Xu Y; Mueller KA; Chen X; Granucci E; Paganoni S; Sadri-Vakili G; Schwarzschild MA
Mol Cell Neurosci; 2018 Oct; 92():12-16. PubMed ID: 29928993
[TBL] [Abstract][Full Text] [Related]
12. Modulation of the IGF1R-MTOR pathway attenuates motor neuron toxicity of human ALS SOD1
Granatiero V; Sayles NM; Savino AM; Konrad C; Kharas MG; Kawamata H; Manfredi G
Autophagy; 2021 Dec; 17(12):4029-4042. PubMed ID: 33749521
[TBL] [Abstract][Full Text] [Related]
13. Increased mitochondrial antioxidative activity or decreased oxygen free radical propagation prevent mutant SOD1-mediated motor neuron cell death and increase amyotrophic lateral sclerosis-like transgenic mouse survival.
Liu R; Li B; Flanagan SW; Oberley LW; Gozal D; Qiu M
J Neurochem; 2002 Feb; 80(3):488-500. PubMed ID: 11905995
[TBL] [Abstract][Full Text] [Related]
14. Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants.
Cassina P; Cassina A; Pehar M; Castellanos R; Gandelman M; de León A; Robinson KM; Mason RP; Beckman JS; Barbeito L; Radi R
J Neurosci; 2008 Apr; 28(16):4115-22. PubMed ID: 18417691
[TBL] [Abstract][Full Text] [Related]
15. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
Jaarsma D; Haasdijk ED; Grashorn JA; Hawkins R; van Duijn W; Verspaget HW; London J; Holstege JC
Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261
[TBL] [Abstract][Full Text] [Related]
16. Enhancing mitochondrial calcium buffering capacity reduces aggregation of misfolded SOD1 and motor neuron cell death without extending survival in mouse models of inherited amyotrophic lateral sclerosis.
Parone PA; Da Cruz S; Han JS; McAlonis-Downes M; Vetto AP; Lee SK; Tseng E; Cleveland DW
J Neurosci; 2013 Mar; 33(11):4657-71. PubMed ID: 23486940
[TBL] [Abstract][Full Text] [Related]
17. Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis.
Urushitani M; Kurisu J; Tsukita K; Takahashi R
J Neurochem; 2002 Dec; 83(5):1030-42. PubMed ID: 12437574
[TBL] [Abstract][Full Text] [Related]
18. Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis.
Pehar M; Cassina P; Vargas MR; Castellanos R; Viera L; Beckman JS; Estévez AG; Barbeito L
J Neurochem; 2004 Apr; 89(2):464-73. PubMed ID: 15056289
[TBL] [Abstract][Full Text] [Related]
19. Amyotrophic lateral sclerosis-related mutant superoxide dismutase 1 aggregates inhibit 14-3-3-mediated cell survival by sequestration into the JUNQ compartment.
Park JH; Jang HR; Lee IY; Oh HK; Choi EJ; Rhim H; Kang S
Hum Mol Genet; 2017 Sep; 26(18):3615-3629. PubMed ID: 28666328
[TBL] [Abstract][Full Text] [Related]
20. Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons.
Nagai M; Re DB; Nagata T; Chalazonitis A; Jessell TM; Wichterle H; Przedborski S
Nat Neurosci; 2007 May; 10(5):615-22. PubMed ID: 17435755
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
