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4. Membrane Interactions Accelerate the Self-Aggregation of Huntingtin Exon 1 Fragments in a Polyglutamine Length-Dependent Manner. Marquette A; Aisenbrey C; Bechinger B Int J Mol Sci; 2021 Jun; 22(13):. PubMed ID: 34201610 [TBL] [Abstract][Full Text] [Related]
5. The Polyglutamine Expansion at the N-Terminal of Huntingtin Protein Modulates the Dynamic Configuration and Phosphorylation of the C-Terminal HEAT Domain. Jung T; Shin B; Tamo G; Kim H; Vijayvargia R; Leitner A; Marcaida MJ; Astorga-Wells J; Jung R; Aebersold R; Peraro MD; Hebert H; Seong IS; Song JJ Structure; 2020 Sep; 28(9):1035-1050.e8. PubMed ID: 32668197 [TBL] [Abstract][Full Text] [Related]
10. Polyglutamine domain flexibility mediates the proximity between flanking sequences in huntingtin. Caron NS; Desmond CR; Xia J; Truant R Proc Natl Acad Sci U S A; 2013 Sep; 110(36):14610-5. PubMed ID: 23898200 [TBL] [Abstract][Full Text] [Related]
11. The folding equilibrium of huntingtin exon 1 monomer depends on its polyglutamine tract. Bravo-Arredondo JM; Kegulian NC; Schmidt T; Pandey NK; Situ AJ; Ulmer TS; Langen R J Biol Chem; 2018 Dec; 293(51):19613-19623. PubMed ID: 30315108 [TBL] [Abstract][Full Text] [Related]
12. Structural insights into the aggregation mechanism of huntingtin exon 1 protein fragment with different polyQ-lengths. Priya SB; Gromiha MM J Cell Biochem; 2019 Jun; 120(6):10519-10529. PubMed ID: 30672003 [TBL] [Abstract][Full Text] [Related]
13. The 17-residue-long N terminus in huntingtin controls stepwise aggregation in solution and on membranes via different mechanisms. Pandey NK; Isas JM; Rawat A; Lee RV; Langen J; Pandey P; Langen R J Biol Chem; 2018 Feb; 293(7):2597-2605. PubMed ID: 29282287 [TBL] [Abstract][Full Text] [Related]
14. Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex. Huang B; Guo Q; Niedermeier ML; Cheng J; Engler T; Maurer M; Pautsch A; Baumeister W; Stengel F; Kochanek S; Fernández-Busnadiego R Structure; 2021 Aug; 29(8):804-809.e5. PubMed ID: 33909994 [TBL] [Abstract][Full Text] [Related]
15. The predominantly HEAT-like motif structure of huntingtin and its association and coincident nuclear entry with dorsal, an NF-kB/Rel/dorsal family transcription factor. Takano H; Gusella JF BMC Neurosci; 2002 Oct; 3():15. PubMed ID: 12379151 [TBL] [Abstract][Full Text] [Related]
17. Fibril polymorphism affects immobilized non-amyloid flanking domains of huntingtin exon1 rather than its polyglutamine core. Lin HK; Boatz JC; Krabbendam IE; Kodali R; Hou Z; Wetzel R; Dolga AM; Poirier MA; van der Wel PCA Nat Commun; 2017 May; 8():15462. PubMed ID: 28537272 [TBL] [Abstract][Full Text] [Related]
18. Does N-terminal huntingtin function as a 'holdase' for inhibiting cellular protein aggregation? Sethi R; Tripathi N; Pallapati AR; Gaikar A; Bharatam PV; Roy I FEBS J; 2018 May; 285(10):1791-1811. PubMed ID: 29630769 [TBL] [Abstract][Full Text] [Related]
19. Free-Energy Landscape of the Amino-Terminal Fragment of Huntingtin in Aqueous Solution. Binette V; Côté S; Mousseau N Biophys J; 2016 Mar; 110(5):1075-88. PubMed ID: 26958885 [TBL] [Abstract][Full Text] [Related]
20. Phosphorylation of huntingtin at residue T3 is decreased in Huntington's disease and modulates mutant huntingtin protein conformation. Cariulo C; Azzollini L; Verani M; Martufi P; Boggio R; Chiki A; Deguire SM; Cherubini M; Gines S; Marsh JL; Conforti P; Cattaneo E; Santimone I; Squitieri F; Lashuel HA; Petricca L; Caricasole A Proc Natl Acad Sci U S A; 2017 Dec; 114(50):E10809-E10818. PubMed ID: 29162692 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]