231 related articles for article (PubMed ID: 27006450)
1. Up-regulation of the mammalian target of rapamycin complex 1 subunit Raptor by aldosterone induces abnormal pulmonary artery smooth muscle cell survival patterns to promote pulmonary arterial hypertension.
Aghamohammadzadeh R; Zhang YY; Stephens TE; Arons E; Zaman P; Polach KJ; Matar M; Yung LM; Yu PB; Bowman FP; Opotowsky AR; Waxman AB; Loscalzo J; Leopold JA; Maron BA
FASEB J; 2016 Jul; 30(7):2511-27. PubMed ID: 27006450
[TBL] [Abstract][Full Text] [Related]
2. Mammalian target of rapamycin complex 2 (mTORC2) coordinates pulmonary artery smooth muscle cell metabolism, proliferation, and survival in pulmonary arterial hypertension.
Goncharov DA; Kudryashova TV; Ziai H; Ihida-Stansbury K; DeLisser H; Krymskaya VP; Tuder RM; Kawut SM; Goncharova EA
Circulation; 2014 Feb; 129(8):864-74. PubMed ID: 24270265
[TBL] [Abstract][Full Text] [Related]
3. Rapamycin attenuates BAFF-extended proliferation and survival via disruption of mTORC1/2 signaling in normal and neoplastic B-lymphoid cells.
Zeng Q; Qin S; Zhang H; Liu B; Qin J; Wang X; Zhang R; Liu C; Dong X; Zhang S; Huang S; Chen L
J Cell Physiol; 2018 Jan; 233(1):516-529. PubMed ID: 28300280
[TBL] [Abstract][Full Text] [Related]
4. Intestinal cell kinase (ICK) promotes activation of mTOR complex 1 (mTORC1) through phosphorylation of Raptor Thr-908.
Wu D; Chapman JR; Wang L; Harris TE; Shabanowitz J; Hunt DF; Fu Z
J Biol Chem; 2012 Apr; 287(15):12510-9. PubMed ID: 22356909
[TBL] [Abstract][Full Text] [Related]
5. Involvement of the bone morphogenetic protein system in endothelin- and aldosterone-induced cell proliferation of pulmonary arterial smooth muscle cells isolated from human patients with pulmonary arterial hypertension.
Yamanaka R; Otsuka F; Nakamura K; Yamashita M; Otani H; Takeda M; Matsumoto Y; Kusano KF; Ito H; Makino H
Hypertens Res; 2010 May; 33(5):435-45. PubMed ID: 20186146
[TBL] [Abstract][Full Text] [Related]
6. Calpain-2 activates Akt via TGF-β1-mTORC2 pathway in pulmonary artery smooth muscle cells.
Abeyrathna P; Kovacs L; Han W; Su Y
Am J Physiol Cell Physiol; 2016 Jul; 311(1):C24-34. PubMed ID: 27099352
[TBL] [Abstract][Full Text] [Related]
7. Pharmacological Inhibition of mTOR Kinase Reverses Right Ventricle Remodeling and Improves Right Ventricle Structure and Function in Rats.
Pena A; Kobir A; Goncharov D; Goda A; Kudryashova TV; Ray A; Vanderpool R; Baust J; Chang B; Mora AL; Gorcsan J; Goncharova EA
Am J Respir Cell Mol Biol; 2017 Nov; 57(5):615-625. PubMed ID: 28679058
[TBL] [Abstract][Full Text] [Related]
8. Akt-dependent activation of mTORC1 complex involves phosphorylation of mTOR (mammalian target of rapamycin) by IκB kinase α (IKKα).
Dan HC; Ebbs A; Pasparakis M; Van Dyke T; Basseres DS; Baldwin AS
J Biol Chem; 2014 Sep; 289(36):25227-40. PubMed ID: 24990947
[TBL] [Abstract][Full Text] [Related]
9. Loss of DP1 Aggravates Vascular Remodeling in Pulmonary Arterial Hypertension via mTORC1 Signaling.
He Y; Zuo C; Jia D; Bai P; Kong D; Chen D; Liu G; Li J; Wang Y; Chen G; Yan S; Xiao B; Zhang J; Piao L; Li Y; Deng Y; Li B; Roux PP; Andreasson KI; Breyer RM; Su Y; Wang J; Lyu A; Shen Y; Yu Y
Am J Respir Crit Care Med; 2020 May; 201(10):1263-1276. PubMed ID: 31917615
[No Abstract] [Full Text] [Related]
10. Selective Tuberous Sclerosis Complex 1 Gene Deletion in Smooth Muscle Activates Mammalian Target of Rapamycin Signaling and Induces Pulmonary Hypertension.
Houssaini A; Abid S; Derumeaux G; Wan F; Parpaleix A; Rideau D; Marcos E; Kebe K; Czibik G; Sawaki D; Treins C; Dubois-Randé JL; Li Z; Amsellem V; Lipskaia L; Pende M; Adnot S
Am J Respir Cell Mol Biol; 2016 Sep; 55(3):352-67. PubMed ID: 26991739
[TBL] [Abstract][Full Text] [Related]
11. mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells.
Le Bacquer O; Queniat G; Gmyr V; Kerr-Conte J; Lefebvre B; Pattou F
J Endocrinol; 2013 Jan; 216(1):21-9. PubMed ID: 23092880
[TBL] [Abstract][Full Text] [Related]
12. Rapamycin-Induced Hypoxia Inducible Factor 2A Is Essential for Chondrogenic Differentiation of Amniotic Fluid Stem Cells.
Preitschopf A; Schörghofer D; Kinslechner K; Schütz B; Zwickl H; Rosner M; Joó JG; Nehrer S; Hengstschläger M; Mikula M
Stem Cells Transl Med; 2016 May; 5(5):580-90. PubMed ID: 27025692
[TBL] [Abstract][Full Text] [Related]
13. Activation of mTORC1 is essential for β-adrenergic stimulation of adipose browning.
Liu D; Bordicchia M; Zhang C; Fang H; Wei W; Li JL; Guilherme A; Guntur K; Czech MP; Collins S
J Clin Invest; 2016 May; 126(5):1704-16. PubMed ID: 27018708
[TBL] [Abstract][Full Text] [Related]
14. PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.
Woo SY; Kim DH; Jun CB; Kim YM; Haar EV; Lee SI; Hegg JW; Bandhakavi S; Griffin TJ; Kim DH
J Biol Chem; 2007 Aug; 282(35):25604-12. PubMed ID: 17599906
[TBL] [Abstract][Full Text] [Related]
15. Calcineurin/NFAT Signaling Modulates Pulmonary Artery Smooth Muscle Cell Proliferation, Migration and Apoptosis in Monocrotaline-Induced Pulmonary Arterial Hypertension Rats.
He RL; Wu ZJ; Liu XR; Gui LX; Wang RX; Lin MJ
Cell Physiol Biochem; 2018; 49(1):172-189. PubMed ID: 30134231
[TBL] [Abstract][Full Text] [Related]
16. GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling.
Stretton C; Hoffmann TM; Munson MJ; Prescott A; Taylor PM; Ganley IG; Hundal HS
Biochem J; 2015 Sep; 470(2):207-21. PubMed ID: 26348909
[TBL] [Abstract][Full Text] [Related]
17. Conditional Disruption of Raptor Reveals an Essential Role for mTORC1 in B Cell Development, Survival, and Metabolism.
Iwata TN; Ramírez JA; Tsang M; Park H; Margineantu DH; Hockenbery DM; Iritani BM
J Immunol; 2016 Sep; 197(6):2250-60. PubMed ID: 27521345
[TBL] [Abstract][Full Text] [Related]
18. Interferon-gamma induces human vascular smooth muscle cell proliferation and intimal expansion by phosphatidylinositol 3-kinase dependent mammalian target of rapamycin raptor complex 1 activation.
Wang Y; Bai Y; Qin L; Zhang P; Yi T; Teesdale SA; Zhao L; Pober JS; Tellides G
Circ Res; 2007 Sep; 101(6):560-9. PubMed ID: 17656678
[TBL] [Abstract][Full Text] [Related]
19. mTORC1 inhibition increases neurotensin secretion and gene expression through activation of the MEK/ERK/c-Jun pathway in the human endocrine cell line BON.
Li J; Liu J; Song J; Wang X; Weiss HL; Townsend CM; Gao T; Evers BM
Am J Physiol Cell Physiol; 2011 Jul; 301(1):C213-26. PubMed ID: 21508335
[TBL] [Abstract][Full Text] [Related]
20. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]