BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

465 related articles for article (PubMed ID: 27008269)

  • 1. Targeting GLI1 Suppresses Cell Growth and Enhances Chemosensitivity in CD34+ Enriched Acute Myeloid Leukemia Progenitor Cells.
    Long B; Wang LX; Zheng FM; Lai SP; Xu DR; Hu Y; Lin DJ; Zhang XZ; Dong L; Long ZJ; Tong XZ; Liu Q
    Cell Physiol Biochem; 2016; 38(4):1288-302. PubMed ID: 27008269
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Curcumin reduces expression of Bcl-2, leading to apoptosis in daunorubicin-insensitive CD34+ acute myeloid leukemia cell lines and primary sorted CD34+ acute myeloid leukemia cells.
    Rao J; Xu DR; Zheng FM; Long ZJ; Huang SS; Wu X; Zhou WH; Huang RW; Liu Q
    J Transl Med; 2011 May; 9():71. PubMed ID: 21595920
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hh/Gli antagonist in acute myeloid leukemia with CBFA2T3-GLIS2 fusion gene.
    Masetti R; Bertuccio SN; Astolfi A; Chiarini F; Lonetti A; Indio V; De Luca M; Bandini J; Serravalle S; Franzoni M; Pigazzi M; Martelli AM; Basso G; Locatelli F; Pession A
    J Hematol Oncol; 2017 Jan; 10(1):26. PubMed ID: 28109323
    [TBL] [Abstract][Full Text] [Related]  

  • 4. GLI1 reduces drug sensitivity by regulating cell cycle through PI3K/AKT/GSK3/CDK pathway in acute myeloid leukemia.
    Zhou C; Du J; Zhao L; Liu W; Zhao T; Liang H; Fang P; Zhang K; Zeng H
    Cell Death Dis; 2021 Mar; 12(3):231. PubMed ID: 33658491
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Gli inhibitor GANT61 suppresses cell proliferation, promotes cell apoptosis and induces G1/G0 cycle retardation with a dose- and time-dependent manner through inhibiting Notch pathway in multiple myeloma.
    Zhang Z; Hao C; Zhang R; Pei X; Li J; Wang L
    Cell Cycle; 2020 Aug; 19(16):2063-2073. PubMed ID: 32677544
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Small-molecule inhibition of BRD4 as a new potent approach to eliminate leukemic stem- and progenitor cells in acute myeloid leukemia AML.
    Herrmann H; Blatt K; Shi J; Gleixner KV; Cerny-Reiterer S; Müllauer L; Vakoc CR; Sperr WR; Horny HP; Bradner JE; Zuber J; Valent P
    Oncotarget; 2012 Dec; 3(12):1588-99. PubMed ID: 23249862
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting the PI3K/AKT pathway via GLI1 inhibition enhanced the drug sensitivity of acute myeloid leukemia cells.
    Liang H; Zheng QL; Fang P; Zhang J; Zhang T; Liu W; Guo M; Robinson CL; Chen SB; Chen XP; Chen FP; Zeng H
    Sci Rep; 2017 Jan; 7():40361. PubMed ID: 28098170
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic Effects.
    Wellbrock J; Latuske E; Köhler J; Wagner K; Stamm H; Vettorazzi E; Vohwinkel G; Klokow M; Uibeleisen R; Ehm P; Riecken K; Loges S; Thol F; Schubert C; Amling M; Jücker M; Bokemeyer C; Heuser M; Krauter J; Fiedler W
    Clin Cancer Res; 2015 May; 21(10):2388-98. PubMed ID: 25745035
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Anti-cell growth and anti-cancer stem cell activities of the non-canonical hedgehog inhibitor GANT61 in triple-negative breast cancer cells.
    Koike Y; Ohta Y; Saitoh W; Yamashita T; Kanomata N; Moriya T; Kurebayashi J
    Breast Cancer; 2017 Sep; 24(5):683-693. PubMed ID: 28144905
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combined inhibition of GLI and FLT3 signaling leads to effective anti-leukemic effects in human acute myeloid leukemia.
    Latuske EM; Stamm H; Klokow M; Vohwinkel G; Muschhammer J; Bokemeyer C; Jücker M; Kebenko M; Fiedler W; Wellbrock J
    Oncotarget; 2017 Apr; 8(17):29187-29201. PubMed ID: 28418873
    [TBL] [Abstract][Full Text] [Related]  

  • 11. GANT61 Reduces Hedgehog Molecule (GLI1) Expression and Promotes Apoptosis in Metastatic Oral Squamous Cell Carcinoma Cells.
    Bacelar Sacramento de Araújo T; de Oliveira Siquara da Rocha L; Torres Andion Vidal M; Cerqueira Coelho PL; Galvão Dos Reis M; Solano de Freitas Souza B; Botelho Pereira Soares M; Almeida Pereira T; Della Coletta R; Pereira Bezerra D; Borges Dias R; Araújo Gurgel Rocha C
    Int J Mol Sci; 2020 Aug; 21(17):. PubMed ID: 32846867
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hedgehog/GLI1 activation leads to leukemic transformation of myelodysplastic syndrome in vivo and GLI1 inhibition results in antitumor activity.
    Lau BW; Huh K; Madero-Marroquin R; De Marchi F; Lim Y; Wang Q; Lobo F; Marchionni L; Smith DB; DeZern A; Levis MJ; Aplan PD; Matsui W; Gondek LP
    Oncogene; 2019 Jan; 38(5):687-698. PubMed ID: 30171262
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Widespread Expression of Hedgehog Pathway Components in a Large Panel of Human Tumor Cells and Inhibition of Tumor Growth by GANT61: Implications for Cancer Therapy.
    Réda J; Vachtenheim J; Vlčková K; Horák P; Vachtenheim J; Ondrušová L
    Int J Mol Sci; 2018 Sep; 19(9):. PubMed ID: 30201866
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Acquired expression of osteopontin selectively promotes enrichment of leukemia stem cells through AKT/mTOR/PTEN/β-catenin pathways in AML cells.
    Mohammadi S; Ghaffari SH; Shaiegan M; Zarif MN; Nikbakht M; Akbari Birgani S; Alimoghadam K; Ghavamzadeh A
    Life Sci; 2016 May; 152():190-8. PubMed ID: 27063991
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Gli inhibitor GANT61 causes apoptosis in myeloid leukemia cells and acts in synergy with rapamycin.
    Pan D; Li Y; Li Z; Wang Y; Wang P; Liang Y
    Leuk Res; 2012 Jun; 36(6):742-8. PubMed ID: 22398221
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Potential role of Shh-Gli1-BMI1 signaling pathway nexus in glioma chemoresistance.
    Shahi MH; Farheen S; Mariyath MP; Castresana JS
    Tumour Biol; 2016 Nov; 37(11):15107-15114. PubMed ID: 27662839
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human stem cell factor-antibody [anti-SCF] enhances chemotherapy cytotoxicity in human CD34+ resistant myeloid leukaemia cells.
    Lu C; Hassan HT
    Leuk Res; 2006 Mar; 30(3):296-302. PubMed ID: 16112192
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of autophagy as a treatment strategy for p53 wild-type acute myeloid leukemia.
    Folkerts H; Hilgendorf S; Wierenga ATJ; Jaques J; Mulder AB; Coffer PJ; Schuringa JJ; Vellenga E
    Cell Death Dis; 2017 Jul; 8(7):e2927. PubMed ID: 28703806
    [TBL] [Abstract][Full Text] [Related]  

  • 19. RepSox slows decay of CD34+ acute myeloid leukemia cells and decreases T cell immunoglobulin mucin-3 expression.
    Jajosky AN; Coad JE; Vos JA; Martin KH; Senft JR; Wenger SL; Gibson LF
    Stem Cells Transl Med; 2014 Jul; 3(7):836-48. PubMed ID: 24855276
    [TBL] [Abstract][Full Text] [Related]  

  • 20. BH3 mimetic ABT-737 induces apoptosis in CD34
    Rao J; Li F; Zhang RY; Zhou HH; Chen GA
    Asia Pac J Clin Oncol; 2017 Apr; 13(2):e144-e152. PubMed ID: 26552712
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.