BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

292 related articles for article (PubMed ID: 27010561)

  • 1. Dynamic Allostery Mediated by a Conserved Tryptophan in the Tec Family Kinases.
    Chopra N; Wales TE; Joseph RE; Boyken SE; Engen JR; Jernigan RL; Andreotti AH
    PLoS Comput Biol; 2016 Mar; 12(3):e1004826. PubMed ID: 27010561
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of an allosteric signaling network within Tec family kinases.
    Joseph RE; Xie Q; Andreotti AH
    J Mol Biol; 2010 Oct; 403(2):231-42. PubMed ID: 20826165
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A conserved isoleucine maintains the inactive state of Bruton's tyrosine kinase.
    Boyken SE; Chopra N; Xie Q; Joseph RE; Wales TE; Fulton DB; Engen JR; Jernigan RL; Andreotti AH
    J Mol Biol; 2014 Oct; 426(21):3656-69. PubMed ID: 25193673
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lipid-targeting pleckstrin homology domain turns its autoinhibitory face toward the TEC kinases.
    Amatya N; Wales TE; Kwon A; Yeung W; Joseph RE; Fulton DB; Kannan N; Engen JR; Andreotti AH
    Proc Natl Acad Sci U S A; 2019 Oct; 116(43):21539-21544. PubMed ID: 31591208
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Controlling the activity of the Tec kinase Itk by mutation of the phenylalanine gatekeeper residue.
    Joseph RE; Andreotti AH
    Biochemistry; 2011 Jan; 50(2):221-9. PubMed ID: 21138328
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-based network analysis of activation mechanisms in the ErbB family of receptor tyrosine kinases: the regulatory spine residues are global mediators of structural stability and allosteric interactions.
    James KA; Verkhivker GM
    PLoS One; 2014; 9(11):e113488. PubMed ID: 25427151
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Solution structure of the SH3 domain from Bruton's tyrosine kinase.
    Hansson H; Mattsson PT; Allard P; Haapaniemi P; Vihinen M; Smith CI; Hard T
    Biochemistry; 1998 Mar; 37(9):2912-24. PubMed ID: 9485443
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutational analysis of the SH2-kinase linker region of Bruton's tyrosine kinase defines alternative modes of regulation for cytoplasmic tyrosine kinase families.
    Guo S; Wahl MI; Witte ON
    Int Immunol; 2006 Jan; 18(1):79-87. PubMed ID: 16291652
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases.
    Marcotte DJ; Liu YT; Arduini RM; Hession CA; Miatkowski K; Wildes CP; Cullen PF; Hong V; Hopkins BT; Mertsching E; Jenkins TJ; Romanowski MJ; Baker DP; Silvian LF
    Protein Sci; 2010 Mar; 19(3):429-39. PubMed ID: 20052711
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation loop dynamics determine the different catalytic efficiencies of B cell- and T cell-specific tec kinases.
    Joseph RE; Kleino I; Wales TE; Xie Q; Fulton DB; Engen JR; Berg LJ; Andreotti AH
    Sci Signal; 2013 Aug; 6(290):ra76. PubMed ID: 23982207
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure of the PH domain and Btk motif from Bruton's tyrosine kinase: molecular explanations for X-linked agammaglobulinaemia.
    Hyvönen M; Saraste M
    EMBO J; 1997 Jun; 16(12):3396-404. PubMed ID: 9218782
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural basis for X-linked agammaglobulinemia (XLA): mutations at interacting Btk residues R562, W563, and A582.
    Maniar HS; Vihinen M; Webster AD; Nilsson L; Smith CI
    Clin Immunol Immunopathol; 1995 Sep; 76(3 Pt 2):S198-202. PubMed ID: 7554468
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular and structural characterization of five novel mutations in the Bruton's tyrosine kinase gene from patients with X-linked agammaglobulinemia.
    Saha BK; Curtis SK; Vogler LB; Vihinen M
    Mol Med; 1997 Jul; 3(7):477-85. PubMed ID: 9260159
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Missense mutations affecting a conserved cysteine pair in the TH domain of Btk.
    Vihinen M; Nore BF; Mattsson PT; Bäckesjö CM; Nars M; Koutaniemi S; Watanabe C; Lester T; Jones A; Ochs HD; Smith CI
    FEBS Lett; 1997 Aug; 413(2):205-10. PubMed ID: 9280283
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A specific intermolecular association between the regulatory domains of a Tec family kinase.
    Brazin KN; Fulton DB; Andreotti AH
    J Mol Biol; 2000 Sep; 302(3):607-23. PubMed ID: 10986122
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural basis for chromosome X-linked agammaglobulinemia: a tyrosine kinase disease.
    Vihinen M; Vetrie D; Maniar HS; Ochs HD; Zhu Q; Vorechovský I; Webster AD; Notarangelo LD; Nilsson L; Sowadski JM
    Proc Natl Acad Sci U S A; 1994 Dec; 91(26):12803-7. PubMed ID: 7809124
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Achieving a Graded Immune Response: BTK Adopts a Range of Active/Inactive Conformations Dictated by Multiple Interdomain Contacts.
    Joseph RE; Wales TE; Fulton DB; Engen JR; Andreotti AH
    Structure; 2017 Oct; 25(10):1481-1494.e4. PubMed ID: 28867612
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of a Novel Class of Covalent Dual Inhibitors Targeting the Protein Kinases BMX and BTK.
    Forster M; Liang XJ; Schröder M; Gerstenecker S; Chaikuad A; Knapp S; Laufer S; Gehringer M
    Int J Mol Sci; 2020 Dec; 21(23):. PubMed ID: 33291717
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A phosphorylation site in Bruton's tyrosine kinase selectively regulates B cell calcium signaling efficiency by altering phospholipase C-gamma activation.
    Guo S; Ferl GZ; Deora R; Riedinger M; Yin S; Kerwin JL; Loo JA; Witte ON
    Proc Natl Acad Sci U S A; 2004 Sep; 101(39):14180-5. PubMed ID: 15375214
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Screening and Characterization of Allosteric Small Molecules Targeting Bruton's Tyrosine Kinase.
    Kueffer LE; Lin DY; Amatya N; Serrenho J; Joseph RE; Courtney AH; Andreotti AH
    Biochemistry; 2024 Jan; 63(1):94-106. PubMed ID: 38091504
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.