118 related articles for article (PubMed ID: 27013400)
1. Hepatocellular Disposition and Transporter Interactions with Tolvaptan and Metabolites in Sandwich-Cultured Human Hepatocytes.
Lu Y; Slizgi JR; Brouwer KR; Claire RL; Freeman KM; Pan M; Brock WJ; Brouwer KL
Drug Metab Dispos; 2016 Jun; 44(6):867-70. PubMed ID: 27013400
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of Human Hepatic Bile Acid Transporters by Tolvaptan and Metabolites: Contributing Factors to Drug-Induced Liver Injury?
Slizgi JR; Lu Y; Brouwer KR; St Claire RL; Freeman KM; Pan M; Brock WJ; Brouwer KL
Toxicol Sci; 2016 Jan; 149(1):237-50. PubMed ID: 26507107
[TBL] [Abstract][Full Text] [Related]
3. Alpha-naphthylisothiocyanate modulates hepatobiliary transporters in sandwich-cultured rat hepatocytes.
Guo C; He L; Yao D; A J; Cao B; Ren J; Wang G; Pan G
Toxicol Lett; 2014 Jan; 224(1):93-100. PubMed ID: 24120425
[TBL] [Abstract][Full Text] [Related]
4. Probe Cocktail to Assess Transporter Function in Sandwich-Cultured Human Hepatocytes.
Guo C; Brouwer KR; Stewart PW; Mosley C; Brouwer KLR
J Pharm Pharm Sci; 2019; 22(1):567-575. PubMed ID: 31804919
[TBL] [Abstract][Full Text] [Related]
5. Culture period-dependent changes in the uptake of transporter substrates in sandwich-cultured rat and human hepatocytes.
Kotani N; Maeda K; Watanabe T; Hiramatsu M; Gong LK; Bi YA; Takezawa T; Kusuhara H; Sugiyama Y
Drug Metab Dispos; 2011 Sep; 39(9):1503-10. PubMed ID: 21673128
[TBL] [Abstract][Full Text] [Related]
6. Characterization of digoxin uptake in sandwich-cultured human hepatocytes.
Kimoto E; Chupka J; Xiao Y; Bi YA; Duignan DB
Drug Metab Dispos; 2011 Jan; 39(1):47-53. PubMed ID: 20926619
[TBL] [Abstract][Full Text] [Related]
7. Assessment of drug interactions in hepatobiliary transport using rhodamine 123 in sandwich-cultured rat hepatocytes.
Annaert PP; Brouwer KL
Drug Metab Dispos; 2005 Mar; 33(3):388-94. PubMed ID: 15608134
[TBL] [Abstract][Full Text] [Related]
8. Hepatic Disposition of Gemfibrozil and Its Major Metabolite Gemfibrozil 1-O-β-Glucuronide.
Kimoto E; Li R; Scialis RJ; Lai Y; Varma MV
Mol Pharm; 2015 Nov; 12(11):3943-52. PubMed ID: 26378985
[TBL] [Abstract][Full Text] [Related]
9. Species differences in hepatobiliary disposition of taurocholic acid in human and rat sandwich-cultured hepatocytes: implications for drug-induced liver injury.
Yang K; Pfeifer ND; Köck K; Brouwer KL
J Pharmacol Exp Ther; 2015 May; 353(2):415-23. PubMed ID: 25711339
[TBL] [Abstract][Full Text] [Related]
10. Confocal imaging with a fluorescent bile acid analogue closely mimicking hepatic taurocholate disposition.
De Bruyn T; Sempels W; Snoeys J; Holmstock N; Chatterjee S; Stieger B; Augustijns P; Hofkens J; Mizuno H; Annaert P
J Pharm Sci; 2014 Jun; 103(6):1872-81. PubMed ID: 24652646
[TBL] [Abstract][Full Text] [Related]
11. Biliary excretion of pravastatin and taurocholate in rats with bile salt export pump (Bsep) impairment.
Cheng Y; Freeden C; Zhang Y; Abraham P; Shen H; Wescott D; Humphreys WG; Gan J; Lai Y
Biopharm Drug Dispos; 2016 Jul; 37(5):276-86. PubMed ID: 27059119
[TBL] [Abstract][Full Text] [Related]
12. Quantitative Systems Toxicology Modeling Predicts that Reduced Biliary Efflux Contributes to Tolvaptan Hepatotoxicity.
Beaudoin JJ; Brock WJ; Watkins PB; Brouwer KLR
Clin Pharmacol Ther; 2021 Feb; 109(2):433-442. PubMed ID: 32748396
[TBL] [Abstract][Full Text] [Related]
13. Hepatocyte-based in vitro model for assessment of drug-induced cholestasis.
Chatterjee S; Richert L; Augustijns P; Annaert P
Toxicol Appl Pharmacol; 2014 Jan; 274(1):124-36. PubMed ID: 24211272
[TBL] [Abstract][Full Text] [Related]
14. Determination of OATP-, NTCP- and OCT-mediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytes.
De Bruyn T; Ye ZW; Peeters A; Sahi J; Baes M; Augustijns PF; Annaert PP
Eur J Pharm Sci; 2011 Jul; 43(4):297-307. PubMed ID: 21605667
[TBL] [Abstract][Full Text] [Related]
15. Polygoni Multiflori Radix derived anthraquinones alter bile acid disposition in sandwich-cultured rat hepatocytes.
Kang L; Si L; Rao J; Li D; Wu Y; Wu S; Wu M; He S; Zhu W; Wu Y; Xu J; Li G; Huang J
Toxicol In Vitro; 2017 Apr; 40():313-323. PubMed ID: 28161596
[TBL] [Abstract][Full Text] [Related]
16. Characterization of organic anion transporting polypeptide (OATP) expression and its functional contribution to the uptake of substrates in human hepatocytes.
Kimoto E; Yoshida K; Balogh LM; Bi YA; Maeda K; El-Kattan A; Sugiyama Y; Lai Y
Mol Pharm; 2012 Dec; 9(12):3535-42. PubMed ID: 23082789
[TBL] [Abstract][Full Text] [Related]
17. Mathematical modeling of the in vitro hepatic disposition of mycophenolic acid and its glucuronide in sandwich-cultured human hepatocytes.
Matsunaga N; Wada S; Nakanishi T; Ikenaga M; Ogawa M; Tamai I
Mol Pharm; 2014 Feb; 11(2):568-79. PubMed ID: 24320552
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of P-glycoprotein expression and function by anti-diabetic drugs gliclazide, metformin, and pioglitazone in vitro and in situ.
Abbasi MM; Valizadeh H; Hamishehkar H; Zakeri-Milani P
Res Pharm Sci; 2016; 11(3):177-86. PubMed ID: 27499787
[TBL] [Abstract][Full Text] [Related]
19. Modeling approach for multiple transporters-mediated drug-drug interactions in sandwich-cultured human hepatocytes: effect of cyclosporin A on hepatic disposition of mycophenolic acid phenyl-glucuronide.
Matsunaga N; Suzuki K; Nakanishi T; Ogawa M; Imawaka H; Tamai I
Drug Metab Pharmacokinet; 2015 Apr; 30(2):142-8. PubMed ID: 25989889
[TBL] [Abstract][Full Text] [Related]
20. Effect of P-glycoprotein on the rat intestinal permeability and metabolism of the BDDCS class 1 drug verapamil.
Estudante M; Maya M; Morais JG; Soveral G; Benet LZ
Mol Pharm; 2013 Nov; 10(11):4038-45. PubMed ID: 24044638
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
