BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

267 related articles for article (PubMed ID: 27013679)

  • 1. Deletion of Vax1 from Gonadotropin-Releasing Hormone (GnRH) Neurons Abolishes GnRH Expression and Leads to Hypogonadism and Infertility.
    Hoffmann HM; Trang C; Gong P; Kimura I; Pandolfi EC; Mellon PL
    J Neurosci; 2016 Mar; 36(12):3506-18. PubMed ID: 27013679
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A small population of hypothalamic neurons govern fertility: the critical role of VAX1 in GnRH neuron development and fertility maintenance.
    Hoffmann HM; Mellon PL
    Neurosci Commun (Houst); 2016; 2():. PubMed ID: 28164172
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Homeodomain Transcription Factors Vax1 and Six6 Are Required for SCN Development and Function.
    Pandolfi EC; Breuer JA; Nguyen Huu VA; Talluri T; Nguyen D; Lee JS; Hu R; Bharti K; Skowronska-Krawczyk D; Gorman MR; Mellon PL; Hoffmann HM
    Mol Neurobiol; 2020 Feb; 57(2):1217-1232. PubMed ID: 31705443
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Heterozygous deletion of ventral anterior homeobox (vax1) causes subfertility in mice.
    Hoffmann HM; Tamrazian A; Xie H; Pérez-Millán MI; Kauffman AS; Mellon PL
    Endocrinology; 2014 Oct; 155(10):4043-53. PubMed ID: 25060364
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Deletion of the Homeodomain Protein Six6 From GnRH Neurons Decreases GnRH Gene Expression, Resulting in Infertility.
    Pandolfi EC; Tonsfeldt KJ; Hoffmann HM; Mellon PL
    Endocrinology; 2019 Sep; 160(9):2151-2164. PubMed ID: 31211355
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transcriptional interaction between cFOS and the homeodomain-binding transcription factor VAX1 on the GnRH promoter controls Gnrh1 expression levels in a GnRH neuron maturation specific manner.
    Hoffmann HM; Gong P; Tamrazian A; Mellon PL
    Mol Cell Endocrinol; 2018 Feb; 461():143-154. PubMed ID: 28890143
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hypothalamic dysregulation and infertility in mice lacking the homeodomain protein Six6.
    Larder R; Clark DD; Miller NL; Mellon PL
    J Neurosci; 2011 Jan; 31(2):426-38. PubMed ID: 21228153
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A Novel Gonadotropin-Releasing Hormone 1 (Gnrh1) Enhancer-Derived Noncoding RNA Regulates Gnrh1 Gene Expression in GnRH Neuronal Cell Models.
    Huang PP; Brusman LE; Iyer AK; Webster NJ; Mellon PL
    PLoS One; 2016; 11(7):e0158597. PubMed ID: 27389022
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Haploinsufficiency of Homeodomain Proteins Six3, Vax1, and Otx2 Causes Subfertility in Mice via Distinct Mechanisms.
    Hoffmann HM; Pandolfi EC; Larder R; Mellon PL
    Neuroendocrinology; 2019; 109(3):200-207. PubMed ID: 30261489
    [TBL] [Abstract][Full Text] [Related]  

  • 10. GnRH Neuron-Specific Ablation of Gαq/11 Results in Only Partial Inactivation of the Neuroendocrine-Reproductive Axis in Both Male and Female Mice: In Vivo Evidence for Kiss1r-Coupled Gαq/11-Independent GnRH Secretion.
    Babwah AV; Navarro VM; Ahow M; Pampillo M; Nash C; Fayazi M; Calder M; Elbert A; Urbanski HF; Wettschureck N; Offermanns S; Carroll RS; Bhattacharya M; Tobet SA; Kaiser UB
    J Neurosci; 2015 Sep; 35(37):12903-16. PubMed ID: 26377475
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The transcription factor VAX1 in VIP neurons of the suprachiasmatic nucleus impacts circadian rhythm generation, depressive-like behavior, and the reproductive axis in a sex-specific manner in mice.
    Van Loh BM; Yaw AM; Breuer JA; Jackson B; Nguyen D; Jang K; Ramos F; Ho EV; Cui LJ; Gillette DLM; Sempere LF; Gorman MR; Tonsfeldt KJ; Mellon PL; Hoffmann HM
    Front Endocrinol (Lausanne); 2023; 14():1269672. PubMed ID: 38205198
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Haploinsufficiency of SIX3 Abolishes Male Reproductive Behavior Through Disrupted Olfactory Development, and Impairs Female Fertility Through Disrupted GnRH Neuron Migration.
    Pandolfi EC; Hoffmann HM; Schoeller EL; Gorman MR; Mellon PL
    Mol Neurobiol; 2018 Nov; 55(11):8709-8727. PubMed ID: 29589282
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Deletion of Otx2 in GnRH neurons results in a mouse model of hypogonadotropic hypogonadism.
    Diaczok D; DiVall S; Matsuo I; Wondisford FE; Wolfe AM; Radovick S
    Mol Endocrinol; 2011 May; 25(5):833-46. PubMed ID: 21436260
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The transcription factors SIX3 and VAX1 are required for suprachiasmatic nucleus circadian output and fertility in female mice.
    Hoffmann HM; Meadows JD; Breuer JA; Yaw AM; Nguyen D; Tonsfeldt KJ; Chin AY; Devries BM; Trang C; Oosterhouse HJ; Lee JS; Doser JW; Gorman MR; Welsh DK; Mellon PL
    J Neurosci Res; 2021 Oct; 99(10):2625-2645. PubMed ID: 34212416
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kiss1 is differentially regulated in male and female mice by the homeodomain transcription factor VAX1.
    Lavalle SN; Chou T; Hernandez J; Naing NCP; Tonsfeldt KJ; Hoffmann HM; Mellon PL
    Mol Cell Endocrinol; 2021 Aug; 534():111358. PubMed ID: 34098016
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential CRE Expression in Lhrh-cre and GnRH-cre Alleles and the Impact on Fertility in Otx2-Flox Mice.
    Hoffmann HM; Larder R; Lee JS; Hu RJ; Trang C; Devries BM; Clark DD; Mellon PL
    Neuroendocrinology; 2019; 108(4):328-342. PubMed ID: 30739114
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A microRNA switch regulates the rise in hypothalamic GnRH production before puberty.
    Messina A; Langlet F; Chachlaki K; Roa J; Rasika S; Jouy N; Gallet S; Gaytan F; Parkash J; Tena-Sempere M; Giacobini P; Prevot V
    Nat Neurosci; 2016 Jun; 19(6):835-44. PubMed ID: 27135215
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Otx2 homeoprotein regulates expression from the gonadotropin-releasing hormone proximal promoter.
    Kelley CG; Lavorgna G; Clark ME; Boncinelli E; Mellon PL
    Mol Endocrinol; 2000 Aug; 14(8):1246-56. PubMed ID: 10935548
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Developmental regulation of gonadotropin-releasing hormone gene expression by the MSX and DLX homeodomain protein families.
    Givens ML; Rave-Harel N; Goonewardena VD; Kurotani R; Berdy SE; Swan CH; Rubenstein JL; Robert B; Mellon PL
    J Biol Chem; 2005 May; 280(19):19156-65. PubMed ID: 15743757
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NELF knockout is associated with impaired pubertal development and subfertility.
    Quaynor SD; Ko EK; Chorich LP; Sullivan ME; Demir D; Waller JL; Kim HG; Cameron RS; Layman LC
    Mol Cell Endocrinol; 2015 May; 407():26-36. PubMed ID: 25731822
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.