These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

493 related articles for article (PubMed ID: 27014936)

  • 1. Inhibition of Protease-Epithelial Sodium Channel Signaling Improves Mucociliary Function in Cystic Fibrosis Airways.
    Reihill JA; Walker B; Hamilton RA; Ferguson TE; Elborn JS; Stutts MJ; Harvey BJ; Saint-Criq V; Hendrick SM; Martin SL
    Am J Respir Crit Care Med; 2016 Sep; 194(6):701-10. PubMed ID: 27014936
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SPX-101 Is a Novel Epithelial Sodium Channel-targeted Therapeutic for Cystic Fibrosis That Restores Mucus Transport.
    Scott DW; Walker MP; Sesma J; Wu B; Stuhlmiller TJ; Sabater JR; Abraham WM; Crowder TM; Christensen DJ; Tarran R
    Am J Respir Crit Care Med; 2017 Sep; 196(6):734-744. PubMed ID: 28481660
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The epithelial sodium channel (ENaC) as a therapeutic target for cystic fibrosis lung disease.
    Moore PJ; Tarran R
    Expert Opin Ther Targets; 2018 Aug; 22(8):687-701. PubMed ID: 30028216
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Soluble mediators, not cilia, determine airway surface liquid volume in normal and cystic fibrosis superficial airway epithelia.
    Tarran R; Trout L; Donaldson SH; Boucher RC
    J Gen Physiol; 2006 May; 127(5):591-604. PubMed ID: 16636206
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of neutrophil elastase and its inhibitor EPI-hNE4 on transepithelial sodium transport across normal and cystic fibrosis human nasal epithelial cells.
    Prulière-Escabasse V; Clerici C; Vuagniaux G; Coste A; Escudier E; Planès C
    Respir Res; 2010 Oct; 11(1):141. PubMed ID: 20932306
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ursodeoxycholic acid inhibits ENaC and Na/K pump activity to restore airway surface liquid height in cystic fibrosis bronchial epithelial cells.
    Mroz MS; Harvey BJ
    Steroids; 2019 Nov; 151():108461. PubMed ID: 31344409
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A highly selective, cell-permeable furin inhibitor BOS-318 rescues key features of cystic fibrosis airway disease.
    Douglas LEJ; Reihill JA; Ho MWY; Axten JM; Campobasso N; Schneck JL; Rendina AR; Wilcoxen KM; Martin SL
    Cell Chem Biol; 2022 Jun; 29(6):947-957.e8. PubMed ID: 35202587
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Airway surface liquid volume regulates ENaC by altering the serine protease-protease inhibitor balance: a mechanism for sodium hyperabsorption in cystic fibrosis.
    Myerburg MM; Butterworth MB; McKenna EE; Peters KW; Frizzell RA; Kleyman TR; Pilewski JM
    J Biol Chem; 2006 Sep; 281(38):27942-9. PubMed ID: 16873367
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The epithelial sodium channel (ENaC) as a therapeutic target for cystic fibrosis.
    Shei RJ; Peabody JE; Kaza N; Rowe SM
    Curr Opin Pharmacol; 2018 Dec; 43():152-165. PubMed ID: 30340955
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ENaC inhibitors and airway re-hydration in cystic fibrosis: state of the art.
    Althaus M
    Curr Mol Pharmacol; 2013 Mar; 6(1):3-12. PubMed ID: 23547930
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Preclinical evaluation of the epithelial sodium channel inhibitor AZD5634 and implications on human translation.
    Åstrand A; Libby EF; Shei RJ; Lever JEP; Kaza N; Adewale AT; Boitet E; Edwards L; Hemmerling M; Root J; Lindberg B; Wingren C; Malmgren A; Sabater J; Rowe SM
    Am J Physiol Lung Cell Mol Physiol; 2022 Nov; 323(5):L536-L547. PubMed ID: 36098422
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Prostasin expression is regulated by airway surface liquid volume and is increased in cystic fibrosis.
    Myerburg MM; McKenna EE; Luke CJ; Frizzell RA; Kleyman TR; Pilewski JM
    Am J Physiol Lung Cell Mol Physiol; 2008 May; 294(5):L932-41. PubMed ID: 18310226
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pharmacotherapy of the ion transport defect in cystic fibrosis: role of purinergic receptor agonists and other potential therapeutics.
    Kunzelmann K; Mall M
    Am J Respir Med; 2003; 2(4):299-309. PubMed ID: 14719996
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neutrophil elastase activates near-silent epithelial Na+ channels and increases airway epithelial Na+ transport.
    Caldwell RA; Boucher RC; Stutts MJ
    Am J Physiol Lung Cell Mol Physiol; 2005 May; 288(5):L813-9. PubMed ID: 15640288
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Epithelial Na
    Smith NJ; Solovay CF
    Pharm Pat Anal; 2017 Jul; 6(4):179-188. PubMed ID: 28696180
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Camostat attenuates airway epithelial sodium channel function in vivo through the inhibition of a channel-activating protease.
    Coote K; Atherton-Watson HC; Sugar R; Young A; MacKenzie-Beevor A; Gosling M; Bhalay G; Bloomfield G; Dunstan A; Bridges RJ; Sabater JR; Abraham WM; Tully D; Pacoma R; Schumacher A; Harris J; Danahay H
    J Pharmacol Exp Ther; 2009 May; 329(2):764-74. PubMed ID: 19190233
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Prostasin, a membrane-anchored serine peptidase, regulates sodium currents in JME/CF15 cells, a cystic fibrosis airway epithelial cell line.
    Tong Z; Illek B; Bhagwandin VJ; Verghese GM; Caughey GH
    Am J Physiol Lung Cell Mol Physiol; 2004 Nov; 287(5):L928-35. PubMed ID: 15246975
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cathepsin B contributes to Na+ hyperabsorption in cystic fibrosis airway epithelial cultures.
    Tan CD; Hobbs C; Sameni M; Sloane BF; Stutts MJ; Tarran R
    J Physiol; 2014 Dec; 592(23):5251-68. PubMed ID: 25260629
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Glandular Proteome Identifies Antiprotease Cystatin C as a Critical Modulator of Airway Hydration and Clearance.
    Evans TI; Joo NS; Keiser NW; Yan Z; Tyler SR; Xie W; Zhang Y; Hsiao JJ; Cho HJ; Wright ME; Wine JJ; Engelhardt JF
    Am J Respir Cell Mol Biol; 2016 Apr; 54(4):469-81. PubMed ID: 26334941
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ENaC-mediated effects assessed by MRI in a rat model of hypertonic saline-induced lung hydration.
    Blé FX; Cannet C; Collingwood S; Danahay H; Beckmann N
    Br J Pharmacol; 2010 Jun; 160(4):1008-15. PubMed ID: 20590595
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.