197 related articles for article (PubMed ID: 27021161)
1. Sites of Anesthetic Inhibitory Action on a Cationic Ligand-Gated Ion Channel.
Laurent B; Murail S; Shahsavar A; Sauguet L; Delarue M; Baaden M
Structure; 2016 Apr; 24(4):595-605. PubMed ID: 27021161
[TBL] [Abstract][Full Text] [Related]
2. Common Internal Allosteric Network Links Anesthetic Binding Sites in a Pentameric Ligand-Gated Ion Channel.
Joseph TT; Mincer JS
PLoS One; 2016; 11(7):e0158795. PubMed ID: 27403526
[TBL] [Abstract][Full Text] [Related]
3. Study, by use of coarse-grained models, of the functionally crucial residues and allosteric pathway of anesthetic regulation of the Gloeobacter violaceus ligand-gated ion channel.
Li XY; Xie F; Zhang JC; Su JG
Eur Biophys J; 2014 Dec; 43(12):623-30. PubMed ID: 25367560
[TBL] [Abstract][Full Text] [Related]
4. Propofol binding to the resting state of the gloeobacter violaceus ligand-gated ion channel (GLIC) induces structural changes in the inter- and intrasubunit transmembrane domain (TMD) cavities.
Ghosh B; Satyshur KA; Czajkowski C
J Biol Chem; 2013 Jun; 288(24):17420-31. PubMed ID: 23640880
[TBL] [Abstract][Full Text] [Related]
5. Anesthetic binding in a pentameric ligand-gated ion channel: GLIC.
Chen Q; Cheng MH; Xu Y; Tang P
Biophys J; 2010 Sep; 99(6):1801-9. PubMed ID: 20858424
[TBL] [Abstract][Full Text] [Related]
6. Modulation of the
Faulkner C; Plant DF; de Leeuw NH
Biochemistry; 2019 Dec; 58(48):4804-4808. PubMed ID: 31718178
[TBL] [Abstract][Full Text] [Related]
7. A membrane-embedded pathway delivers general anesthetics to two interacting binding sites in the
Arcario MJ; Mayne CG; Tajkhorshid E
J Biol Chem; 2017 Jun; 292(23):9480-9492. PubMed ID: 28420728
[TBL] [Abstract][Full Text] [Related]
8. X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel.
Nury H; Van Renterghem C; Weng Y; Tran A; Baaden M; Dufresne V; Changeux JP; Sonner JM; Delarue M; Corringer PJ
Nature; 2011 Jan; 469(7330):428-31. PubMed ID: 21248852
[TBL] [Abstract][Full Text] [Related]
9. Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Hu H; Ataka K; Menny A; Fourati Z; Sauguet L; Corringer PJ; Koehl P; Heberle J; Delarue M
Proc Natl Acad Sci U S A; 2018 Dec; 115(52):E12172-E12181. PubMed ID: 30541892
[TBL] [Abstract][Full Text] [Related]
10. Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels.
Fourati Z; Howard RJ; Heusser SA; Hu H; Ruza RR; Sauguet L; Lindahl E; Delarue M
Cell Rep; 2018 Apr; 23(4):993-1004. PubMed ID: 29694907
[TBL] [Abstract][Full Text] [Related]
11. Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC).
Spurny R; Billen B; Howard RJ; Brams M; Debaveye S; Price KL; Weston DA; Strelkov SV; Tytgat J; Bertrand S; Bertrand D; Lummis SCR; Ulens C
J Biol Chem; 2013 Mar; 288(12):8355-8364. PubMed ID: 23364792
[TBL] [Abstract][Full Text] [Related]
12. Allosteric potentiation of a ligand-gated ion channel is mediated by access to a deep membrane-facing cavity.
Heusser SA; Lycksell M; Wang X; McComas SE; Howard RJ; Lindahl E
Proc Natl Acad Sci U S A; 2018 Oct; 115(42):10672-10677. PubMed ID: 30275330
[TBL] [Abstract][Full Text] [Related]
13. Chasing the open-state structure of pentameric ligand-gated ion channels.
Gonzalez-Gutierrez G; Wang Y; Cymes GD; Tajkhorshid E; Grosman C
J Gen Physiol; 2017 Dec; 149(12):1119-1138. PubMed ID: 29089419
[TBL] [Abstract][Full Text] [Related]
14. Structural Basis for Xenon Inhibition in a Cationic Pentameric Ligand-Gated Ion Channel.
Sauguet L; Fourati Z; Prangé T; Delarue M; Colloc'h N
PLoS One; 2016; 11(2):e0149795. PubMed ID: 26910105
[TBL] [Abstract][Full Text] [Related]
15. Un-gating and allosteric modulation of a pentameric ligand-gated ion channel captured by molecular dynamics.
Martin NE; Malik S; Calimet N; Changeux JP; Cecchini M
PLoS Comput Biol; 2017 Oct; 13(10):e1005784. PubMed ID: 29069080
[TBL] [Abstract][Full Text] [Related]
16. Structural basis for allosteric transitions of a multidomain pentameric ligand-gated ion channel.
Hu H; Howard RJ; Bastolla U; Lindahl E; Delarue M
Proc Natl Acad Sci U S A; 2020 Jun; 117(24):13437-13446. PubMed ID: 32482881
[TBL] [Abstract][Full Text] [Related]
17. Mapping two neurosteroid-modulatory sites in the prototypic pentameric ligand-gated ion channel GLIC.
Cheng WWL; Chen ZW; Bracamontes JR; Budelier MM; Krishnan K; Shin DJ; Wang C; Jiang X; Covey DF; Akk G; Evers AS
J Biol Chem; 2018 Feb; 293(8):3013-3027. PubMed ID: 29301936
[TBL] [Abstract][Full Text] [Related]
18. Direct Pore Binding as a Mechanism for Isoflurane Inhibition of the Pentameric Ligand-gated Ion Channel ELIC.
Chen Q; Kinde MN; Arjunan P; Wells MM; Cohen AE; Xu Y; Tang P
Sci Rep; 2015 Sep; 5():13833. PubMed ID: 26346220
[TBL] [Abstract][Full Text] [Related]
19. A chimeric prokaryotic-eukaryotic pentameric ligand gated ion channel reveals interactions between the extracellular and transmembrane domains shape neurosteroid modulation.
Ghosh B; Tsao TW; Czajkowski C
Neuropharmacology; 2017 Oct; 125():343-352. PubMed ID: 28803966
[TBL] [Abstract][Full Text] [Related]
20. Functional validation of virtual screening for novel agents with general anesthetic action at ligand-gated ion channels.
Heusser SA; Howard RJ; Borghese CM; Cullins MA; Broemstrup T; Lee US; Lindahl E; Carlsson J; Harris RA
Mol Pharmacol; 2013 Nov; 84(5):670-8. PubMed ID: 23950219
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]