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BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

121 related articles for article (PubMed ID: 27024140)

  • 1. Ask the doctor. I have a family history of cardiovascular disease. Although I don't have high blood pressure, high cholesterol, diabetes, or any other risk factor, I'm concerned about how my cardiologist is screening me, because women can have small-vessel disease and not necessarily arterial disease. How should I be screened?
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  • 2. I've heard that statins can can help lower C-reactive proteins (CRP) levels. I'm 65, but I don't take a statin because my cholesterol is low. Should I be concerned about CRP? I have a family history of heart disease.
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  • 3. On call. I've been taking Zocor since my heart attack in 2006. My cholesterol count has come way down, and I haven't had any heart problems. In the past few months, however, I've had some muscle aches. My blood tests don't show any muscle damage, but my doctor says Zocor may still be causing the problem. He wants me to stop Zocor for a while, but I'm worried about my heart. Is it safe for me to stop?
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  • 4. I'm a postmenopausal woman. My doctor wants me to take a statin to lower my cholesterol. Is it safe for me to take statins?
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  • 5. By the way, doctor. My cholesterol numbers are as follows: Total-220; HDL-82 (it's been anywhere from 75 to 85 for the last 20 years); LDL-150; total-to-HDL ratio-2.7. I'm 85, and the heart doctor wants to put me on a statin. I feel great; I'm not overweight, and I don't have any heart problems. I don't take any medications except a daily 81-mg baby aspirin. Do I need to take a statin?
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  • 6. Ask the doctor. I am 75 and have had atrial fibrillation for a while. I take digoxin, lisinopril, Coumadin, and Lipitor. My medications seem to work, but I'm still concerned about the big difference between my systolic and diastolic blood pressure readings. The systolic is usually between 130 and 150 and the diastolic is between 55 and 70. Should I worry about this?
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  • 7. On call. I was recently diagnosed with gout. I'm feeling well with medication, but my doctor want me to take drugs for my cholesterol and blood pressure because gout will raise my risk of heart attack. I don't want to take more pills. What do you think?
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  • 8. On call. I've always been completely healthy. At my last check-up, my cholesterol was 295. I'm worried, but my doctor tells me I don't need treatment. What do you suggest?
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  • 9. Ask the doctor. I'm a 42-year-old man with no health problems, except for the fact that I'm a bit overweight. I recently had an exercise test because of some chest pain. The good news is that it showed no evidence of heart problems, but during the test my blood pressure quickly shop up to 190 mm Hg. Usually, it's about 35/90 mm Hg. The doctor doing the test didn't seem too alarmed, but I'm concerned.
    Lee TH
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  • 10. Ask the doctor. During a recent appointment, my cardiologist heard a sound in my neck and sent me for a ultrasound, which showed a narrowing in my carotid artery. The doctor said this means I'm at risk for a stroke. Because I'm already taking all the right medicines, his only recommendation was getting another ultrasound in a year. But if the narrowing gets worse and I have a stroke, won't that be too late?
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  • 11. Ask the doctor. At age 62 I'm a bit overweight and have diabetes. I take a statin, and my LDL cholesterol is good (84 mg/dL). But my HDL is low (30 mg/dL) and my triglycerides are above 300 mg/dL. Are high triglycerides a problem?
    Lee TH
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  • 12. Ask the doctors. I used to see a cardiologist for mild high blood pressure, and she performed a cardiac ultrasound, electrocardiogram, and stress test with nuclear imaging every year. I felt reassured when my test results were normal. I had to switch to a new cardiologist, and he routinely does an electrocardiogram, but no other tests. He says I'm doing fine, and that I don't need those tests every year. Am I being neglected? I am not getting as much attention as I used to?
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  • 13. Ask the Doctor. I'm 45 years old. At the doctor's office, my blood pressure readings are usually pretty high (the top number may reach 150 or 160), but my home monitor shows numbers more like 130/90. My doctor calls my problem "white-coat hypertension" and reassures me that it isn't dangerous. But it bothers me that my pressure shoots up like that. I have plenty of stressful moments every day, and my blood pressure must be going up then, too. Should I be on medication?
    Lee TH
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  • 14. Ask the doctors. I have coronary artery disease, and my primary care doctor just told me that changes in my tests indicate I have prediabetes. This doesn't sound like a big deal, since I don't need medicines yet. But I'm wondering if I should start doing anything differently?
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  • 15. Ask the doctor. I'm a cancer survivor and take a calcium-channel blocker for high blood pressure. I recently read that these medications can cause cancer. But it's the only drug that's worked well for me. Should I stop taking it?
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  • 16. Can you tell me about "white-coat syndrome?" When I'm at the doctor's office, my blood pressure can get as high as 220/110. But when I take my blood pressure at home, it is 130/84. I have an outgoing personality, so I don't think it's bottled tension!
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  • 17. Ask the doctor. I try to exercise every day to raise my heart rate. The standard formula of 220 minus age (I'm 79) times 0.9 gives an excessively high target for me. Because my resting heart rate is under 50, I would need to more than double my heart rate to reach a target of 128. Does the standard formula apply to people like me?
    Lee TH
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  • 18. Ask the doctor. My doctor and I are confused by my cholesterol levels. My good cholesterol is extraordinarily high, at 94, but my bad cholesterol is on the high side, too, at 154. To resolve this good news/bad news story, my doctor ordered a C-reactive protein test which, of course, came back right in the middle of the normal range. I don't smoke or have other factors for heart disease. Would you advise me at start a statin or some other drug?
    Lee T
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  • 19. By the way, doctor... Exercise: nothing to fear. I'm 62, pretty trim, but I don't particularly enjoy exercise. My wife keeps telling me I need to be more physically active. But I've heard of several people who died during or shortly after exercise. If I don't need to lose weight, why should I expose myself to danger doing something I don't enjoy?
    Lee TH
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  • 20. By the way, doctor. I'm 84 and had a small heart attack last year. My kids tell me I should be taking a statin. But at my age, I don't see how any medication is going to clean out my arteries and get rid of my atherosclerosis. What do you think?
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