These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 27025153)

  • 1. Convergent and Modular Synthesis of Candidate Precolibactins. Structural Revision of Precolibactin A.
    Healy AR; Vizcaino MI; Crawford JM; Herzon SB
    J Am Chem Soc; 2016 Apr; 138(16):5426-32. PubMed ID: 27025153
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A Mechanistic Model for Colibactin-Induced Genotoxicity.
    Healy AR; Nikolayevskiy H; Patel JR; Crawford JM; Herzon SB
    J Am Chem Soc; 2016 Dec; 138(48):15563-15570. PubMed ID: 27934011
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and reactivity of precolibactin 886.
    Healy AR; Wernke KM; Kim CS; Lees NR; Crawford JM; Herzon SB
    Nat Chem; 2019 Oct; 11(10):890-898. PubMed ID: 31548676
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Colibactin Genotoxin Generates DNA Interstrand Cross-Links in Infected Cells.
    Bossuet-Greif N; Vignard J; Taieb F; Mirey G; Dubois D; Petit C; Oswald E; Nougayrède JP
    mBio; 2018 Mar; 9(2):. PubMed ID: 29559578
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Domain-Targeted Metabolomics Delineates the Heterocycle Assembly Steps of Colibactin Biosynthesis.
    Trautman EP; Healy AR; Shine EE; Herzon SB; Crawford JM
    J Am Chem Soc; 2017 Mar; 139(11):4195-4201. PubMed ID: 28240912
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular Basis of Gut Microbiome-Associated Colorectal Cancer: A Synthetic Perspective.
    Healy AR; Herzon SB
    J Am Chem Soc; 2017 Oct; 139(42):14817-14824. PubMed ID: 28949546
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ClbS Is a Cyclopropane Hydrolase That Confers Colibactin Resistance.
    Tripathi P; Shine EE; Healy AR; Kim CS; Herzon SB; Bruner SD; Crawford JM
    J Am Chem Soc; 2017 Dec; 139(49):17719-17722. PubMed ID: 29112397
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vivo evidence for a prodrug activation mechanism during colibactin maturation.
    Bian X; Fu J; Plaza A; Herrmann J; Pistorius D; Stewart AF; Zhang Y; Müller R
    Chembiochem; 2013 Jul; 14(10):1194-7. PubMed ID: 23744512
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of Natural Colibactin-Nucleobase Adducts by Tandem Mass Spectrometry and Isotopic Labeling. Support for DNA Alkylation by Cyclopropane Ring Opening.
    Xue M; Shine E; Wang W; Crawford JM; Herzon SB
    Biochemistry; 2018 Nov; 57(45):6391-6394. PubMed ID: 30365310
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Isolation of New Colibactin Metabolites from Wild-Type
    Zhou T; Hirayama Y; Tsunematsu Y; Suzuki N; Tanaka S; Uchiyama N; Goda Y; Yoshikawa Y; Iwashita Y; Sato M; Miyoshi N; Mutoh M; Ishikawa H; Sugimura H; Wakabayashi K; Watanabe K
    J Am Chem Soc; 2021 Apr; 143(14):5526-5533. PubMed ID: 33787233
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ClbR Is the Key Transcriptional Activator of Colibactin Gene Expression in Escherichia coli.
    Wallenstein A; Rehm N; Brinkmann M; Selle M; Bossuet-Greif N; Sauer D; Bunk B; Spröer C; Wami HT; Homburg S; von Bünau R; König S; Nougayrède JP; Overmann J; Oswald E; Müller R; Dobrindt U
    mSphere; 2020 Jul; 5(4):. PubMed ID: 32669458
    [TBL] [Abstract][Full Text] [Related]  

  • 12.
    Kim CS; Turocy T; Moon G; Shine EE; Crawford JM
    Org Lett; 2021 Sep; 23(17):6895-6899. PubMed ID: 34406772
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Model Colibactins Exhibit Human Cell Genotoxicity in the Absence of Host Bacteria.
    Shine EE; Xue M; Patel JR; Healy AR; Surovtseva YV; Herzon SB; Crawford JM
    ACS Chem Biol; 2018 Dec; 13(12):3286-3293. PubMed ID: 30403848
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Employing chemical synthesis to study the structure and function of colibactin, a "dark matter" metabolite.
    Williams PC; Wernke KM; Tirla A; Herzon SB
    Nat Prod Rep; 2020 Nov; 37(11):1532-1548. PubMed ID: 33174565
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Probing Microbiome Genotoxicity: A Stable Colibactin Provides Insight into Structure-Activity Relationships and Facilitates Mechanism of Action Studies.
    Wernke KM; Tirla A; Xue M; Surovtseva YV; Menges FS; Herzon SB
    J Am Chem Soc; 2021 Sep; 143(38):15824-15833. PubMed ID: 34524796
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Two more pieces of the colibactin genotoxin puzzle from
    Bian X; Plaza A; Zhang Y; Müller R
    Chem Sci; 2015 May; 6(5):3154-3160. PubMed ID: 28706687
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of Polyketide Synthase Machinery from the pks Island Facilitates Isolation of a Candidate Precolibactin.
    Zha L; Wilson MR; Brotherton CA; Balskus EP
    ACS Chem Biol; 2016 May; 11(5):1287-95. PubMed ID: 26890481
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Critical Intermediates Reveal New Biosynthetic Events in the Enigmatic Colibactin Pathway.
    Li ZR; Li Y; Lai JY; Tang J; Wang B; Lu L; Zhu G; Wu X; Xu Y; Qian PY
    Chembiochem; 2015 Aug; 16(12):1715-9. PubMed ID: 26052818
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A prodrug resistance mechanism is involved in colibactin biosynthesis and cytotoxicity.
    Brotherton CA; Balskus EP
    J Am Chem Soc; 2013 Mar; 135(9):3359-62. PubMed ID: 23406518
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure and Functional Analysis of ClbQ, an Unusual Intermediate-Releasing Thioesterase from the Colibactin Biosynthetic Pathway.
    Guntaka NS; Healy AR; Crawford JM; Herzon SB; Bruner SD
    ACS Chem Biol; 2017 Oct; 12(10):2598-2608. PubMed ID: 28846367
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.