These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 27025983)

  • 21. The novel UGT1A9 intronic I399 polymorphism appears as a predictor of 7-ethyl-10-hydroxycamptothecin glucuronidation levels in the liver.
    Girard H; Villeneuve L; Court MH; Fortier LC; Caron P; Hao Q; von Moltke LL; Greenblatt DJ; Guillemette C
    Drug Metab Dispos; 2006 Jul; 34(7):1220-8. PubMed ID: 16595709
    [TBL] [Abstract][Full Text] [Related]  

  • 22. N-Glucuronidation of the antiepileptic drug retigabine: results from studies with human volunteers, heterologously expressed human UGTs, human liver, kidney, and liver microsomal membranes of Crigler-Najjar type II.
    Borlak J; Gasparic A; Locher M; Schupke H; Hermann R
    Metabolism; 2006 Jun; 55(6):711-21. PubMed ID: 16713428
    [TBL] [Abstract][Full Text] [Related]  

  • 23. How many and which amino acids are responsible for the large activity differences between the highly homologous UDP-glucuronosyltransferases (UGT) 1A9 and UGT1A10?
    Itäaho K; Laakkonen L; Finel M
    Drug Metab Dispos; 2010 Apr; 38(4):687-96. PubMed ID: 20089735
    [TBL] [Abstract][Full Text] [Related]  

  • 24. An investigation of human and rat liver microsomal mycophenolic acid glucuronidation: evidence for a principal role of UGT1A enzymes and species differences in UGT1A specificity.
    Miles KK; Stern ST; Smith PC; Kessler FK; Ali S; Ritter JK
    Drug Metab Dispos; 2005 Oct; 33(10):1513-20. PubMed ID: 16033946
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Effects of coexpression of UGT1A9 on enzymatic activities of human UGT1A isoforms.
    Fujiwara R; Nakajima M; Yamanaka H; Nakamura A; Katoh M; Ikushiro S; Sakaki T; Yokoi T
    Drug Metab Dispos; 2007 May; 35(5):747-57. PubMed ID: 17293379
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Glucuronidation of edaravone by human liver and kidney microsomes: biphasic kinetics and identification of UGT1A9 as the major UDP-glucuronosyltransferase isoform.
    Ma L; Sun J; Peng Y; Zhang R; Shao F; Hu X; Zhu J; Wang X; Cheng X; Zhu Y; Wan P; Feng D; Wu H; Wang G
    Drug Metab Dispos; 2012 Apr; 40(4):734-41. PubMed ID: 22238289
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Human UDP-glucuronosyltransferase 1A1 is the primary enzyme responsible for the N-glucuronidation of N-hydroxy-PhIP in vitro.
    Malfatti MA; Felton JS
    Chem Res Toxicol; 2004 Aug; 17(8):1137-44. PubMed ID: 15310245
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Influence of mutations associated with Gilbert and Crigler-Najjar type II syndromes on the glucuronidation kinetics of bilirubin and other UDP-glucuronosyltransferase 1A substrates.
    Udomuksorn W; Elliot DJ; Lewis BC; Mackenzie PI; Yoovathaworn K; Miners JO
    Pharmacogenet Genomics; 2007 Dec; 17(12):1017-29. PubMed ID: 18004206
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Differences in UGT1A1, UGT1A7, and UGT1A9 polymorphisms between Uzbek and Japanese populations.
    Maeda H; Hazama S; Shavkat A; Okamoto K; Oba K; Sakamoto J; Takahashi K; Oka M; Nakamura D; Tsunedomi R; Okayama N; Mishima H; Kobayashi M
    Mol Diagn Ther; 2014 Jun; 18(3):333-42. PubMed ID: 24453052
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Interindividual variability in acetaminophen glucuronidation by human liver microsomes: identification of relevant acetaminophen UDP-glucuronosyltransferase isoforms.
    Court MH; Duan SX; von Moltke LL; Greenblatt DJ; Patten CJ; Miners JO; Mackenzie PI
    J Pharmacol Exp Ther; 2001 Dec; 299(3):998-1006. PubMed ID: 11714888
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Modulation of the human glucuronosyltransferase UGT1A pathway by splice isoform polypeptides is mediated through protein-protein interactions.
    Bellemare J; Rouleau M; Harvey M; Guillemette C
    J Biol Chem; 2010 Feb; 285(6):3600-3607. PubMed ID: 19996319
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Acyl glucuronidation of fluoroquinolone antibiotics by the UDP-glucuronosyltransferase 1A subfamily in human liver microsomes.
    Tachibana M; Tanaka M; Masubuchi Y; Horie T
    Drug Metab Dispos; 2005 Jun; 33(6):803-11. PubMed ID: 15769885
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Preparation of a specific monoclonal antibody against human UDP-glucuronosyltransferase (UGT) 1A9 and evaluation of UGT1A9 protein levels in human tissues.
    Oda S; Nakajima M; Hatakeyama M; Fukami T; Yokoi T
    Drug Metab Dispos; 2012 Aug; 40(8):1620-7. PubMed ID: 22619308
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The "albumin effect" and drug glucuronidation: bovine serum albumin and fatty acid-free human serum albumin enhance the glucuronidation of UDP-glucuronosyltransferase (UGT) 1A9 substrates but not UGT1A1 and UGT1A6 activities.
    Rowland A; Knights KM; Mackenzie PI; Miners JO
    Drug Metab Dispos; 2008 Jun; 36(6):1056-62. PubMed ID: 18362158
    [TBL] [Abstract][Full Text] [Related]  

  • 35. cDNA cloning and functional analysis of minipig uridine diphosphate-glucuronosyltransferase 1A1.
    Miyake Y; Mayumi K; Jinno H; Tanaka-Kagawa T; Narimatsu S; Hanioka N
    Biol Pharm Bull; 2013; 36(3):452-61. PubMed ID: 23449330
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Effect of a conserved mutation in uridine diphosphate glucuronosyltransferase 1A1 and 1A6 on glucuronidation of a metabolite of flutamide.
    Ito M; Yamamoto K; Maruo Y; Sato H; Fujiyama Y; Bamba T
    Eur J Clin Pharmacol; 2002 Apr; 58(1):11-4. PubMed ID: 11956667
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Characterization of the uridine diphosphate-glucuronosyltransferase-catalyzing thyroid hormone glucuronidation in man.
    Findlay KA; Kaptein E; Visser TJ; Burchell B
    J Clin Endocrinol Metab; 2000 Aug; 85(8):2879-83. PubMed ID: 10946897
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Functional characterization of low-prevalence missense polymorphisms in the UDP-glucuronosyltransferase 1A9 gene.
    Olson KC; Dellinger RW; Zhong Q; Sun D; Amin S; Spratt TE; Lazarus P
    Drug Metab Dispos; 2009 Oct; 37(10):1999-2007. PubMed ID: 19589876
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The UDP-glucuronosyltransferase 2B7 isozyme is responsible for gemfibrozil glucuronidation in the human liver.
    Mano Y; Usui T; Kamimura H
    Drug Metab Dispos; 2007 Nov; 35(11):2040-4. PubMed ID: 17670842
    [TBL] [Abstract][Full Text] [Related]  

  • 40. N-Glycosylation plays a role in protein folding of human UGT1A9.
    Nakajima M; Koga T; Sakai H; Yamanaka H; Fujiwara R; Yokoi T
    Biochem Pharmacol; 2010 Apr; 79(8):1165-72. PubMed ID: 19951703
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.