358 related articles for article (PubMed ID: 27028870)
1. An optimized single chain TCR scaffold relying on the assembly with the native CD3-complex prevents residual mispairing with endogenous TCRs in human T-cells.
Knies D; Klobuch S; Xue SA; Birtel M; Echchannaoui H; Yildiz O; Omokoko T; Guillaume P; Romero P; Stauss H; Sahin U; Herr W; Theobald M; Thomas S; Voss RH
Oncotarget; 2016 Apr; 7(16):21199-221. PubMed ID: 27028870
[TBL] [Abstract][Full Text] [Related]
2. Coexpression of the T-cell receptor constant alpha domain triggers tumor reactivity of single-chain TCR-transduced human T cells.
Voss RH; Thomas S; Pfirschke C; Hauptrock B; Klobuch S; Kuball J; Grabowski M; Engel R; Guillaume P; Romero P; Huber C; Beckhove P; Theobald M
Blood; 2010 Jun; 115(25):5154-63. PubMed ID: 20378753
[TBL] [Abstract][Full Text] [Related]
3. Human TCR that incorporate CD3zeta induce highly preferred pairing between TCRalpha and beta chains following gene transfer.
Sebestyén Z; Schooten E; Sals T; Zaldivar I; San José E; Alarcón B; Bobisse S; Rosato A; Szöllosi J; Gratama JW; Willemsen RA; Debets R
J Immunol; 2008 Jun; 180(11):7736-46. PubMed ID: 18490778
[TBL] [Abstract][Full Text] [Related]
4. Single-chain VαVβ T-cell receptors function without mispairing with endogenous TCR chains.
Aggen DH; Chervin AS; Schmitt TM; Engels B; Stone JD; Richman SA; Piepenbrink KH; Baker BM; Greenberg PD; Schreiber H; Kranz DM
Gene Ther; 2012 Apr; 19(4):365-74. PubMed ID: 21753797
[TBL] [Abstract][Full Text] [Related]
5. A novel T cell receptor single-chain signaling complex mediates antigen-specific T cell activity and tumor control.
Stone JD; Harris DT; Soto CM; Chervin AS; Aggen DH; Roy EJ; Kranz DM
Cancer Immunol Immunother; 2014 Nov; 63(11):1163-76. PubMed ID: 25082071
[TBL] [Abstract][Full Text] [Related]
6. Transgenic TCR expression: comparison of single chain with full-length receptor constructs for T-cell function.
Zhang T; He X; Tsang TC; Harris DT
Cancer Gene Ther; 2004 Jul; 11(7):487-96. PubMed ID: 15153936
[TBL] [Abstract][Full Text] [Related]
7. Improved expression and reactivity of transduced tumor-specific TCRs in human lymphocytes by specific silencing of endogenous TCR.
Okamoto S; Mineno J; Ikeda H; Fujiwara H; Yasukawa M; Shiku H; Kato I
Cancer Res; 2009 Dec; 69(23):9003-11. PubMed ID: 19903853
[TBL] [Abstract][Full Text] [Related]
8. T-cell synapse formation depends on antigen recognition but not CD3 interaction: studies with TCR:ζ, a candidate transgene for TCR gene therapy.
Roszik J; Sebestyén Z; Govers C; Guri Y; Szöor A; Pályi-Krekk Z; Vereb G; Nagy P; Szöllosi J; Debets R
Eur J Immunol; 2011 May; 41(5):1288-97. PubMed ID: 21469084
[TBL] [Abstract][Full Text] [Related]
9. Novel adoptive T-cell immunotherapy using a WT1-specific TCR vector encoding silencers for endogenous TCRs shows marked antileukemia reactivity and safety.
Ochi T; Fujiwara H; Okamoto S; An J; Nagai K; Shirakata T; Mineno J; Kuzushima K; Shiku H; Yasukawa M
Blood; 2011 Aug; 118(6):1495-503. PubMed ID: 21673345
[TBL] [Abstract][Full Text] [Related]
10. A stable marker for specific T-cells: a TCR alpha/green fluorescent protein (GFP) fusionprotein reconstitutes a functionally active TCR complex.
Schleicher U; Röllinghoff M; Gessner A
J Immunol Methods; 2000 Dec; 246(1-2):165-74. PubMed ID: 11121557
[TBL] [Abstract][Full Text] [Related]
11. Generation of V α13/β21+T cell specific target CML cells by TCR gene transfer.
Zha X; Xu L; Chen S; Yang L; Zhang Y; Lu Y; Yu Z; Li B; Wu X; Zheng W; Li Y
Oncotarget; 2016 Dec; 7(51):84246-84257. PubMed ID: 27713165
[TBL] [Abstract][Full Text] [Related]
12. TCR-NK Cells: A Novel Source for Adoptive Immunotherapy of Cancer.
Karahan ZS; Aras M; Sütlü T
Turk J Haematol; 2023 Feb; 40(1):1-10. PubMed ID: 36719099
[TBL] [Abstract][Full Text] [Related]
13. Structural features of T cell receptor variable regions that enhance domain stability and enable expression as single-chain ValphaVbeta fragments.
Richman SA; Aggen DH; Dossett ML; Donermeyer DL; Allen PM; Greenberg PD; Kranz DM
Mol Immunol; 2009 Feb; 46(5):902-16. PubMed ID: 18962897
[TBL] [Abstract][Full Text] [Related]
14. Optimization of T-cell Reactivity by Exploiting TCR Chain Centricity for the Purpose of Safe and Effective Antitumor TCR Gene Therapy.
Ochi T; Nakatsugawa M; Chamoto K; Tanaka S; Yamashita Y; Guo T; Fujiwara H; Yasukawa M; Butler MO; Hirano N
Cancer Immunol Res; 2015 Sep; 3(9):1070-81. PubMed ID: 25943533
[TBL] [Abstract][Full Text] [Related]
15. γδTCR immunoglobulin constant region domain exchange in human αβTCRs improves TCR pairing without altering TCR gene-modified T cell function.
Tao C; Shao H; Zhang W; Bo H; Wu F; Shen H; Huang S
Mol Med Rep; 2017 Apr; 15(4):1555-1564. PubMed ID: 28259946
[TBL] [Abstract][Full Text] [Related]
16. Functional comparison of engineered T cells carrying a native TCR versus TCR-like antibody-based chimeric antigen receptors indicates affinity/avidity thresholds.
Oren R; Hod-Marco M; Haus-Cohen M; Thomas S; Blat D; Duvshani N; Denkberg G; Elbaz Y; Benchetrit F; Eshhar Z; Stauss H; Reiter Y
J Immunol; 2014 Dec; 193(11):5733-43. PubMed ID: 25362181
[TBL] [Abstract][Full Text] [Related]
17. TCR mispairing in genetically modified T cells was detected by fluorescence resonance energy transfer.
Shao H; Zhang W; Hu Q; Wu F; Shen H; Huang S
Mol Biol Rep; 2010 Dec; 37(8):3951-6. PubMed ID: 20373027
[TBL] [Abstract][Full Text] [Related]
18. A Potent Tumor-Reactive p53-Specific Single-Chain TCR without On- or Off-Target Autoimmunity In Vivo.
Echchannaoui H; Petschenka J; Ferreira EA; Hauptrock B; Lotz-Jenne C; Voss RH; Theobald M
Mol Ther; 2019 Jan; 27(1):261-271. PubMed ID: 30528087
[TBL] [Abstract][Full Text] [Related]
19. An Ig Transmembrane Domain Motif Improves the Function of TCRs Transduced in Human T Cells: Implications for Immunotherapy.
D'Apice L; Cuccaro F; Varriale S; Cipria D; Sartorius R; Circosta P; Cignetti A; Salerno M; Coscia MR; Oreste U; Marzullo VM; Martini G; Acuto O; De Berardinis P
J Immunother; 2019 May; 42(4):97-109. PubMed ID: 30865026
[TBL] [Abstract][Full Text] [Related]
20. T-cell receptors in channel catfish: structure and expression of TCR alpha and beta genes.
Wilson MR; Zhou H; Bengtén E; Clem LW; Stuge TB; Warr GW; Miller NW
Mol Immunol; 1998 Jun; 35(9):545-57. PubMed ID: 9809582
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
