BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 27029323)

  • 21. Nonclassic functions of human topoisomerase I: genome-wide and pharmacologic analyses.
    Miao ZH; Player A; Shankavaram U; Wang YH; Zimonjic DB; Lorenzi PL; Liao ZY; Liu H; Shimura T; Zhang HL; Meng LH; Zhang YW; Kawasaki ES; Popescu NC; Aladjem MI; Goldstein DJ; Weinstein JN; Pommier Y
    Cancer Res; 2007 Sep; 67(18):8752-61. PubMed ID: 17875716
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Clinical and cellular roles for TDP1 and TOP1 in modulating colorectal cancer response to irinotecan.
    Meisenberg C; Gilbert DC; Chalmers A; Haley V; Gollins S; Ward SE; El-Khamisy SF
    Mol Cancer Ther; 2015 Feb; 14(2):575-85. PubMed ID: 25522766
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Topoisomerase I copy number alterations as biomarker for irinotecan efficacy in metastatic colorectal cancer.
    Palshof JA; Høgdall EV; Poulsen TS; Linnemann D; Jensen BV; Pfeiffer P; Tarpgaard LS; Brünner N; Stenvang J; Yilmaz M; Nielsen DL
    BMC Cancer; 2017 Jan; 17(1):48. PubMed ID: 28077117
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Differential and common DNA repair pathways for topoisomerase I- and II-targeted drugs in a genetic DT40 repair cell screen panel.
    Maede Y; Shimizu H; Fukushima T; Kogame T; Nakamura T; Miki T; Takeda S; Pommier Y; Murai J
    Mol Cancer Ther; 2014 Jan; 13(1):214-20. PubMed ID: 24130054
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Differential stabilization of eukaryotic DNA topoisomerase I cleavable complexes by camptothecin derivatives.
    Tanizawa A; Kohn KW; Kohlhagen G; Leteurtre F; Pommier Y
    Biochemistry; 1995 May; 34(21):7200-6. PubMed ID: 7766631
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Effects of drug efflux proteins and topoisomerase I mutations on the camptothecin analogue gimatecan.
    Gounder MK; Nazar AS; Saleem A; Pungaliya P; Kulkarni D; Versace R; Rubin EH
    Invest New Drugs; 2008 Jun; 26(3):205-13. PubMed ID: 17943230
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Acquired irinotecan resistance is accompanied by stable modifications of cell cycle dynamics independent of MSI status.
    Petitprez A; Poindessous V; Ouaret D; Regairaz M; Bastian G; Guérin E; Escargueil AE; Larsen AK
    Int J Oncol; 2013 May; 42(5):1644-53. PubMed ID: 23546019
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Characterization of novel human leukemic cell lines selected for resistance to merbarone, a catalytic inhibitor of DNA topoisomerase II.
    Kusumoto H; Rodgers QE; Boege F; Raimondi SC; Beck WT
    Cancer Res; 1996 Jun; 56(11):2573-83. PubMed ID: 8653700
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Characterization of p53 wild-type and null isogenic colorectal cancer cell lines resistant to 5-fluorouracil, oxaliplatin, and irinotecan.
    Boyer J; McLean EG; Aroori S; Wilson P; McCulla A; Carey PD; Longley DB; Johnston PG
    Clin Cancer Res; 2004 Mar; 10(6):2158-67. PubMed ID: 15041737
    [TBL] [Abstract][Full Text] [Related]  

  • 30. In vivo sequencing of camptothecin-induced topoisomerase I cleavage sites in human colon carcinoma cells.
    Pondarré C; Strumberg D; Fujimori A; Torres-León R; Pommier Y
    Nucleic Acids Res; 1997 Oct; 25(20):4111-6. PubMed ID: 9321666
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Mechanisms of resistance in a human cell line exposed to sequential topoisomerase poisoning.
    Saleem A; Ibrahim N; Patel M; Li XG; Gupta E; Mendoza J; Pantazis P; Rubin EH
    Cancer Res; 1997 Nov; 57(22):5100-6. PubMed ID: 9371509
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Topoisomerase degradation, DSB repair, p53 and IAPs in cancer cell resistance to camptothecin-like topoisomerase I inhibitors.
    Tomicic MT; Kaina B
    Biochim Biophys Acta; 2013 Jan; 1835(1):11-27. PubMed ID: 23006513
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Altered expression of cell proliferation-related and interferon-stimulated genes in colon cancer cells resistant to SN38.
    Gongora C; Candeil L; Vezzio N; Copois V; Denis V; Breil C; Molina F; Fraslon C; Conseiller E; Pau B; Martineau P; Del Rio M
    Cancer Biol Ther; 2008 Jun; 7(6):822-32. PubMed ID: 18340113
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Cullin 3 promotes proteasomal degradation of the topoisomerase I-DNA covalent complex.
    Zhang HF; Tomida A; Koshimizu R; Ogiso Y; Lei S; Tsuruo T
    Cancer Res; 2004 Feb; 64(3):1114-21. PubMed ID: 14871846
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan.
    Meisenberg C; Ashour ME; El-Shafie L; Liao C; Hodgson A; Pilborough A; Khurram SA; Downs JA; Ward SE; El-Khamisy SF
    Nucleic Acids Res; 2017 Feb; 45(3):1159-1176. PubMed ID: 28180300
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Heterozygous disruption of the DNA topoisomerase I gene confers cellular resistance to camptothecin in human cells.
    Toyoda E; Kurosawa A; Fujii M; Adachi N
    Biol Pharm Bull; 2009 Apr; 32(4):724-7. PubMed ID: 19336913
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Combined MET inhibition and topoisomerase I inhibition block cell growth of small cell lung cancer.
    Rolle CE; Kanteti R; Surati M; Nandi S; Dhanasingh I; Yala S; Tretiakova M; Arif Q; Hembrough T; Brand TM; Wheeler DL; Husain AN; Vokes EE; Bharti A; Salgia R
    Mol Cancer Ther; 2014 Mar; 13(3):576-84. PubMed ID: 24327519
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Ubiquitin/26S proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cells.
    Desai SD; Li TK; Rodriguez-Bauman A; Rubin EH; Liu LF
    Cancer Res; 2001 Aug; 61(15):5926-32. PubMed ID: 11479235
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Influence of MLH1 on colon cancer sensitivity to poly(ADP-ribose) polymerase inhibitor combined with irinotecan.
    Tentori L; Leonetti C; Muzi A; Dorio AS; Porru M; Dolci S; Campolo F; Vernole P; Lacal PM; Praz F; Graziani G
    Int J Oncol; 2013 Jul; 43(1):210-8. PubMed ID: 23653048
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Structural insight of DNA topoisomerases I from camptothecin-producing plants revealed by molecular dynamics simulations.
    Sirikantaramas S; Meeprasert A; Rungrotmongkol T; Fuji H; Hoshino T; Sudo H; Yamazaki M; Saito K
    Phytochemistry; 2015 May; 113():50-6. PubMed ID: 25733498
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.