BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

242 related articles for article (PubMed ID: 27030511)

  • 1. Structure Based Docking and Molecular Dynamic Studies of Plasmodial Cysteine Proteases against a South African Natural Compound and its Analogs.
    Musyoka TM; Kanzi AM; Lobb KA; Tastan Bishop Ö
    Sci Rep; 2016 Mar; 6():23690. PubMed ID: 27030511
    [TBL] [Abstract][Full Text] [Related]  

  • 2. South African Abietane Diterpenoids and Their Analogs as Potential Antimalarials: Novel Insights from Hybrid Computational Approaches.
    Musyoka T; Bishop ÖT
    Molecules; 2019 Nov; 24(22):. PubMed ID: 31703388
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Computation-based virtual screening for designing novel antimalarial drugs by targeting falcipain-III: a structure-based drug designing approach.
    Kesharwani RK; Singh DV; Misra K
    J Vector Borne Dis; 2013; 50(2):93-102. PubMed ID: 23995310
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In-Silico molecular docking and simulation studies on novel chalcone and flavone hybrid derivatives with 1, 2, 3-triazole linkage as vital inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase.
    Thillainayagam M; Malathi K; Ramaiah S
    J Biomol Struct Dyn; 2018 Nov; 36(15):3993-4009. PubMed ID: 29132266
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparing sequence and structure of falcipains and human homologs at prodomain and catalytic active site for malarial peptide based inhibitor design.
    Musyoka TM; Njuguna JN; Tastan Bishop Ö
    Malar J; 2019 May; 18(1):159. PubMed ID: 31053072
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of new promising Plasmodium falciparum superoxide dismutase allosteric inhibitors through hierarchical pharmacophore-based virtual screening and molecular dynamics.
    Araujo JSC; de Souza BC; Costa Junior DB; Oliveira LM; Santana IB; Duarte AA; Lacerda PS; Dos Santos Junior MC; Leite FHA
    J Mol Model; 2018 Jul; 24(8):220. PubMed ID: 30056475
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of (4-(9H-fluoren-9-yl) piperazin-1-yl) methanone derivatives as falcipain 2 inhibitors active against Plasmodium falciparum cultures.
    Hernández-González JE; Salas-Sarduy E; Hernández Ramírez LF; Pascual MJ; Álvarez DE; Pabón A; Leite VBP; Pascutti PG; Valiente PA
    Biochim Biophys Acta Gen Subj; 2018 Dec; 1862(12):2911-2923. PubMed ID: 30253205
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of diverse natural products as falcipain-2 inhibitors through structure-based virtual screening.
    Wang L; Zhang S; Zhu J; Zhu L; Liu X; Shan L; Huang J; Zhang W; Li H
    Bioorg Med Chem Lett; 2014 Mar; 24(5):1261-4. PubMed ID: 24530004
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Analysis of non-peptidic compounds as potential malarial inhibitors against Plasmodial cysteine proteases via integrated virtual screening workflow.
    Musyoka TM; Kanzi AM; Lobb KA; Tastan Bishop Ö
    J Biomol Struct Dyn; 2016 Oct; 34(10):2084-101. PubMed ID: 26471975
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of antimalarial leads with dual falcipain-2 and falcipain-3 inhibitory activity.
    Rana D; Kalamuddin M; Sundriyal S; Jaiswal V; Sharma G; Das Sarma K; Sijwali PS; Mohmmed A; Malhotra P; Mahindroo N
    Bioorg Med Chem; 2020 Jan; 28(1):115155. PubMed ID: 31744777
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparative molecular field analysis and molecular docking studies on novel aryl chalcone derivatives against an important drug target cysteine protease in Plasmodium falciparum.
    Thillainayagam M; Anbarasu A; Ramaiah S
    J Theor Biol; 2016 Aug; 403():110-128. PubMed ID: 27185536
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of novel malarial cysteine protease inhibitors using structure-based virtual screening of a focused cysteine protease inhibitor library.
    Shah F; Mukherjee P; Gut J; Legac J; Rosenthal PJ; Tekwani BL; Avery MA
    J Chem Inf Model; 2011 Apr; 51(4):852-64. PubMed ID: 21428453
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, biological evaluation, hydration site thermodynamics, and chemical reactivity analysis of α-keto substituted peptidomimetics for the inhibition of Plasmodium falciparum.
    Weldon DJ; Shah F; Chittiboyina AG; Sheri A; Chada RR; Gut J; Rosenthal PJ; Shivakumar D; Sherman W; Desai P; Jung JC; Avery MA
    Bioorg Med Chem Lett; 2014 Mar; 24(5):1274-9. PubMed ID: 24507921
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of Selective Novel Hits against
    Nyamai DW; Tastan Bishop Ö
    Int J Mol Sci; 2020 May; 21(11):. PubMed ID: 32471245
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological activities of novel artemisinin derivatives as cysteine protease falcipain-2 inhibitors.
    Liu Y; Lu WQ; Cui KQ; Luo W; Wang J; Guo C
    Arch Pharm Res; 2012 Sep; 35(9):1525-31. PubMed ID: 23054708
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Probing the structure of falcipain-3, a cysteine protease from Plasmodium falciparum: comparative protein modeling and docking studies.
    Sabnis YA; Desai PV; Rosenthal PJ; Avery MA
    Protein Sci; 2003 Mar; 12(3):501-9. PubMed ID: 12592020
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Falcipain inhibitors: optimization studies of the 2-pyrimidinecarbonitrile lead series.
    Coterón JM; Catterick D; Castro J; Chaparro MJ; Díaz B; Fernández E; Ferrer S; Gamo FJ; Gordo M; Gut J; de las Heras L; Legac J; Marco M; Miguel J; Muñoz V; Porras E; de la Rosa JC; Ruiz JR; Sandoval E; Ventosa P; Rosenthal PJ; Fiandor JM
    J Med Chem; 2010 Aug; 53(16):6129-52. PubMed ID: 20672841
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dietary flavonoids fisetin and myricetin: dual inhibitors of Plasmodium falciparum falcipain-2 and plasmepsin II.
    Jin H; Xu Z; Cui K; Zhang T; Lu W; Huang J
    Fitoterapia; 2014 Apr; 94():55-61. PubMed ID: 24468190
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Drug target prioritization in Plasmodium falciparum through metabolic network analysis, and inhibitor designing using virtual screening and docking approach.
    Yadav MK; Pandey SK; Swati D
    J Bioinform Comput Biol; 2013 Aug; 11(4):1350003. PubMed ID: 23859267
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, antimalarial activity in vitro, and docking studies of novel neolignan derivatives.
    Pereira GAN; Souza GC; Santos LS; Barata LES; Meneses CCF; Krettli AU; Daniel-Ribeiro CT; Alves CN
    Chem Biol Drug Des; 2017 Sep; 90(3):464-472. PubMed ID: 28245094
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.