BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

306 related articles for article (PubMed ID: 27030595)

  • 1. Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans.
    Castillo SD; Tzouanacou E; Zaw-Thin M; Berenjeno IM; Parker VE; Chivite I; Milà-Guasch M; Pearce W; Solomon I; Angulo-Urarte A; Figueiredo AM; Dewhurst RE; Knox RG; Clark GR; Scudamore CL; Badar A; Kalber TL; Foster J; Stuckey DJ; David AL; Phillips WA; Lythgoe MF; Wilson V; Semple RK; Sebire NJ; Kinsler VA; Graupera M; Vanhaesebroeck B
    Sci Transl Med; 2016 Mar; 8(332):332ra43. PubMed ID: 27030595
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Somatic Activating PIK3CA Mutations Cause Venous Malformation.
    Limaye N; Kangas J; Mendola A; Godfraind C; Schlögel MJ; Helaers R; Eklund L; Boon LM; Vikkula M
    Am J Hum Genet; 2015 Dec; 97(6):914-21. PubMed ID: 26637981
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Somatic PIK3CA mutations as a driver of sporadic venous malformations.
    Castel P; Carmona FJ; Grego-Bessa J; Berger MF; Viale A; Anderson KV; Bague S; Scaltriti M; Antonescu CR; Baselga E; Baselga J
    Sci Transl Med; 2016 Mar; 8(332):332ra42. PubMed ID: 27030594
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A xenograft model for venous malformation.
    Goines J; Li X; Cai Y; Mobberley-Schuman P; Metcalf M; Fishman SJ; Adams DM; Hammill AM; Boscolo E
    Angiogenesis; 2018 Nov; 21(4):725-735. PubMed ID: 29786783
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genetic landscape of common venous malformations in the head and neck.
    Du Z; Liu JL; You YH; Wang LZ; He J; Zheng JW; Zhang ZY; Wang YA
    J Vasc Surg Venous Lymphat Disord; 2021 Jul; 9(4):1007-1016.e7. PubMed ID: 33248299
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comprehensive phenotypic and genomic characterization of venous malformations.
    Hirose K; Hori Y; Ozeki M; Motooka D; Hata K; Tahara S; Matsui T; Kohara M; Maruyama K; Imanaka-Yoshida K; Toyosawa S; Morii E
    Hum Pathol; 2024 Mar; 145():48-55. PubMed ID: 38367816
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CD10 and CD34 as markers in vascular malformations with PIK3CA and TEK mutations.
    Moneghini L; Tosi D; Graziani D; Caretti A; Colletti G; Baraldini V; Cattaneo E; Spaccini L; Zocca A; Bulfamante GP
    Hum Pathol; 2020 May; 99():98-106. PubMed ID: 32272124
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PI3K/mTOR inhibition promotes the regression of experimental vascular malformations driven by PIK3CA-activating mutations.
    di Blasio L; Puliafito A; Gagliardi PA; Comunanza V; Somale D; Chiaverina G; Bussolino F; Primo L
    Cell Death Dis; 2018 Jan; 9(2):45. PubMed ID: 29352118
    [TBL] [Abstract][Full Text] [Related]  

  • 9. AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations.
    Si Y; Huang J; Li X; Fu Y; Xu R; Du Y; Cheng J; Jiang H
    Cell Commun Signal; 2020 Aug; 18(1):139. PubMed ID: 32867785
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Constitutively active PIK3CA mutations are expressed by lymphatic and vascular endothelial cells in capillary lymphatic venous malformation.
    Le Cras TD; Goines J; Lakes N; Pastura P; Hammill AM; Adams DM; Boscolo E
    Angiogenesis; 2020 Aug; 23(3):425-442. PubMed ID: 32350708
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Development of Molecular Therapies for Venous Malformations.
    Kangas J; Nätynki M; Eklund L
    Basic Clin Pharmacol Toxicol; 2018 Sep; 123 Suppl 5():6-19. PubMed ID: 29668117
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A Patient-Derived Xenograft Model for Venous Malformation.
    Schrenk S; Goines J; Boscolo E
    J Vis Exp; 2020 Jun; (160):. PubMed ID: 32597867
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Functional assessment of two variants of unknown significance in TEK by endothelium-specific expression in zebrafish embryos.
    Bell LM; Holm A; Matysiak U; Driever W; Rößler J; Schanze D; Wieland I; Niemeyer CM; Zenker M; Kapp FG
    Hum Mol Genet; 2021 Dec; 31(1):10-17. PubMed ID: 34254124
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rapamycin improves TIE2-mutated venous malformation in murine model and human subjects.
    Boscolo E; Limaye N; Huang L; Kang KT; Soblet J; Uebelhoer M; Mendola A; Natynki M; Seront E; Dupont S; Hammer J; Legrand C; Brugnara C; Eklund L; Vikkula M; Bischoff J; Boon LM
    J Clin Invest; 2015 Sep; 125(9):3491-504. PubMed ID: 26258417
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Somatic mutations in angiopoietin receptor gene TEK cause solitary and multiple sporadic venous malformations.
    Limaye N; Wouters V; Uebelhoer M; Tuominen M; Wirkkala R; Mulliken JB; Eklund L; Boon LM; Vikkula M
    Nat Genet; 2009 Jan; 41(1):118-24. PubMed ID: 19079259
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Common and specific effects of TIE2 mutations causing venous malformations.
    Nätynki M; Kangas J; Miinalainen I; Sormunen R; Pietilä R; Soblet J; Boon LM; Vikkula M; Limaye N; Eklund L
    Hum Mol Genet; 2015 Nov; 24(22):6374-89. PubMed ID: 26319232
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ponatinib Combined With Rapamycin Causes Regression of Murine Venous Malformation.
    Li X; Cai Y; Goines J; Pastura P; Brichta L; Lane A; Le Cras TD; Boscolo E
    Arterioscler Thromb Vasc Biol; 2019 Mar; 39(3):496-512. PubMed ID: 30626204
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The onset of PI3K-related vascular malformations occurs during angiogenesis and is prevented by the AKT inhibitor miransertib.
    Kobialka P; Sabata H; Vilalta O; Gouveia L; Angulo-Urarte A; Muixí L; Zanoncello J; Muñoz-Aznar O; Olaciregui NG; Fanlo L; Esteve-Codina A; Lavarino C; Javierre BM; Celis V; Rovira C; López-Fernández S; Baselga E; Mora J; Castillo SD; Graupera M
    EMBO Mol Med; 2022 Jul; 14(7):e15619. PubMed ID: 35695059
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A Xenograft Model for Venous Malformation.
    Goines J; Boscolo E
    Methods Mol Biol; 2021; 2206():179-192. PubMed ID: 32754818
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Somatic TEK variant with intraarticular venous malformation and knee hemarthrosis treated with rapamycin.
    Adham S; Revencu N; Mestre S; Nou-Howaldt M; Vernhet-Kovacsik H; Quéré I
    Mol Genet Genomic Med; 2022 Jun; 10(6):e1931. PubMed ID: 35426265
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.