These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 27035276)

  • 1. Synthesis and Behavioral Studies of Chiral Cyclopropanes as Selective α4β2-Nicotinic Acetylcholine Receptor Partial Agonists Exhibiting an Antidepressant Profile. Part III.
    Onajole OK; Vallerini GP; Eaton JB; Lukas RJ; Brunner D; Caldarone BJ; Kozikowski AP
    ACS Chem Neurosci; 2016 Jun; 7(6):811-22. PubMed ID: 27035276
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chemistry, pharmacology, and behavioral studies identify chiral cyclopropanes as selective α4β2-nicotinic acetylcholine receptor partial agonists exhibiting an antidepressant profile. Part II.
    Zhang HK; Yu LF; Eaton JB; Whiteaker P; Onajole OK; Hanania T; Brunner D; Lukas RJ; Kozikowski AP
    J Med Chem; 2013 Jul; 56(13):5495-504. PubMed ID: 23734673
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chemistry and behavioral studies identify chiral cyclopropanes as selective α4β2-nicotinic acetylcholine receptor partial agonists exhibiting an antidepressant profile.
    Zhang H; Tückmantel W; Eaton JB; Yuen PW; Yu LF; Bajjuri KM; Fedolak A; Wang D; Ghavami A; Caldarone B; Paterson NE; Lowe DA; Brunner D; Lukas RJ; Kozikowski AP
    J Med Chem; 2012 Jan; 55(2):717-24. PubMed ID: 22171543
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and biological evaluation of novel hybrids of highly potent and selective α4β2-Nicotinic acetylcholine receptor (nAChR) partial agonists.
    Zhang HK; Eaton JB; Fedolak A; Gunosewoyo H; Onajole OK; Brunner D; Lukas RJ; Yu LF; Kozikowski AP
    Eur J Med Chem; 2016 Nov; 124():689-697. PubMed ID: 27639361
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Insights into the structural determinants required for high-affinity binding of chiral cyclopropane-containing ligands to α4β2-nicotinic acetylcholine receptors: an integrated approach to behaviorally active nicotinic ligands.
    Zhang HK; Eaton JB; Yu LF; Nys M; Mazzolari A; van Elk R; Smit AB; Alexandrov V; Hanania T; Sabath E; Fedolak A; Brunner D; Lukas RJ; Vistoli G; Ulens C; Kozikowski AP
    J Med Chem; 2012 Sep; 55(18):8028-37. PubMed ID: 22928944
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antidepressant-like effects of nicotinic acetylcholine receptor antagonists, but not agonists, in the mouse forced swim and mouse tail suspension tests.
    Andreasen JT; Olsen GM; Wiborg O; Redrobe JP
    J Psychopharmacol; 2009 Sep; 23(7):797-804. PubMed ID: 18583432
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dissociation between duration of action in the forced swim test in mice and nicotinic acetylcholine receptor occupancy with sazetidine, varenicline, and 5-I-A85380.
    Caldarone BJ; Wang D; Paterson NE; Manzano M; Fedolak A; Cavino K; Kwan M; Hanania T; Chellappan SK; Kozikowski AP; Olivier B; Picciotto MR; Ghavami A
    Psychopharmacology (Berl); 2011 Sep; 217(2):199-210. PubMed ID: 21487659
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of highly potent and selective α4β2-nicotinic acetylcholine receptor (nAChR) partial agonists containing an isoxazolylpyridine ether scaffold that demonstrate antidepressant-like activity. Part II.
    Yu LF; Eaton JB; Fedolak A; Zhang HK; Hanania T; Brunner D; Lukas RJ; Kozikowski AP
    J Med Chem; 2012 Nov; 55(22):9998-10009. PubMed ID: 23092294
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enantiopure Cyclopropane-Bearing Pyridyldiazabicyclo[3.3.0]octanes as Selective α4β2-nAChR Ligands.
    Onajole OK; Eaton JB; Lukas RJ; Brunner D; Thiede L; Caldarone BJ; Kozikowski AP
    ACS Med Chem Lett; 2014 Nov; 5(11):1196-201. PubMed ID: 25408831
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of isoxazole analogues of sazetidine-A as selective α4β2-nicotinic acetylcholine receptor partial agonists for the treatment of depression.
    Liu J; Yu LF; Eaton JB; Caldarone B; Cavino K; Ruiz C; Terry M; Fedolak A; Wang D; Ghavami A; Lowe DA; Brunner D; Lukas RJ; Kozikowski AP
    J Med Chem; 2011 Oct; 54(20):7280-8. PubMed ID: 21905669
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Subtype-selective nicotinic acetylcholine receptor agonists enhance the responsiveness to citalopram and reboxetine in the mouse forced swim test.
    Andreasen JT; Nielsen EØ; Christensen JK; Olsen GM; Peters D; Mirza NR; Redrobe JP
    J Psychopharmacol; 2011 Oct; 25(10):1347-56. PubMed ID: 20360159
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chemistry and pharmacological characterization of novel nitrogen analogues of AMOP-H-OH (Sazetidine-A, 6-[5-(azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol) as α4β2-nicotinic acetylcholine receptor-selective partial agonists.
    Liu J; Eaton JB; Caldarone B; Lukas RJ; Kozikowski AP
    J Med Chem; 2010 Oct; 53(19):6973-85. PubMed ID: 20822184
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of novel α4β2-nicotinic acetylcholine receptor (nAChR) agonists based on an isoxazole ether scaffold that demonstrate antidepressant-like activity.
    Yu LF; Tückmantel W; Eaton JB; Caldarone B; Fedolak A; Hanania T; Brunner D; Lukas RJ; Kozikowski AP
    J Med Chem; 2012 Jan; 55(2):812-23. PubMed ID: 22148173
    [TBL] [Abstract][Full Text] [Related]  

  • 14. α4β2 nicotinic acetylcholine receptor partial agonists with low intrinsic efficacy have antidepressant-like properties.
    Mineur YS; Einstein EB; Seymour PA; Coe JW; O'neill BT; Rollema H; Picciotto MR
    Behav Pharmacol; 2011 Aug; 22(4):291-9. PubMed ID: 21566524
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chemistry and pharmacology of nicotinic ligands based on 6-[5-(azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol (AMOP-H-OH) for possible use in depression.
    Kozikowski AP; Eaton JB; Bajjuri KM; Chellappan SK; Chen Y; Karadi S; He R; Caldarone B; Manzano M; Yuen PW; Lukas RJ
    ChemMedChem; 2009 Aug; 4(8):1279-91. PubMed ID: 19569163
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Procognitive effects of varenicline in the animal model of schizophrenia depend on α4β2- and α 7-nicotinic acetylcholine receptors.
    Potasiewicz A; Golebiowska J; Popik P; Nikiforuk A
    J Psychopharmacol; 2018 Dec; 33(1):269881118812097. PubMed ID: 30501536
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The potent and selective α4β2*/α6*-nicotinic acetylcholine receptor partial agonist 2-[5-[5-((S)Azetidin-2-ylmethoxy)-3-pyridinyl]-3-isoxazolyl]ethanol demonstrates antidepressive-like behavior in animal models and a favorable ADME-tox profile.
    Yu LF; Brek Eaton J; Zhang HK; Sabath E; Hanania T; Li GN; van Breemen RB; Whiteaker P; Liu Q; Wu J; Chang YC; Lukas RJ; Brunner D; Kozikowski AP
    Pharmacol Res Perspect; 2014 Apr; 2(2):e00026. PubMed ID: 25505580
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SSR591813, a novel selective and partial alpha4beta2 nicotinic receptor agonist with potential as an aid to smoking cessation.
    Cohen C; Bergis OE; Galli F; Lochead AW; Jegham S; Biton B; Leonardon J; Avenet P; Sgard F; Besnard F; Graham D; Coste A; Oblin A; Curet O; Voltz C; Gardes A; Caille D; Perrault G; George P; Soubrie P; Scatton B
    J Pharmacol Exp Ther; 2003 Jul; 306(1):407-20. PubMed ID: 12682217
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Neonicotinic analogues: selective antagonists for α4β2 nicotinic acetylcholine receptors.
    Faundez-Parraguez M; Farias-Rabelo N; Gonzalez-Gutierrez JP; Etcheverry-Berrios A; Alzate-Morales J; Adasme-Carreño F; Varas R; Bermudez I; Iturriaga-Vasquez P
    Bioorg Med Chem; 2013 May; 21(10):2687-94. PubMed ID: 23561269
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In vitro and in vivo neuronal nicotinic receptor properties of (+)- and (-)-pyrido[3,4]homotropane [(+)- and (-)-PHT]: (+)-PHT is a potent and selective full agonist at α6β2 containing neuronal nicotinic acetylcholine receptors.
    Carroll FI; Navarro HA; Mascarella SW; Castro AH; Luetje CW; Wageman CR; Marks MJ; Jackson A; Damaj MI
    ACS Chem Neurosci; 2015 Jun; 6(6):920-6. PubMed ID: 25891987
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.