346 related articles for article (PubMed ID: 27036734)
1. Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta.
Kuzuya A; Zoltowska KM; Post KL; Arimon M; Li X; Svirsky S; Maesako M; Muzikansky A; Gautam V; Kovacs D; Hyman BT; Berezovska O
BMC Biol; 2016 Mar; 14():25. PubMed ID: 27036734
[TBL] [Abstract][Full Text] [Related]
2. Dynamic presenilin 1 and synaptotagmin 1 interaction modulates exocytosis and amyloid β production.
Zoltowska KM; Maesako M; Lushnikova I; Takeda S; Keller LJ; Skibo G; Hyman BT; Berezovska O
Mol Neurodegener; 2017 Feb; 12(1):15. PubMed ID: 28193235
[TBL] [Abstract][Full Text] [Related]
3. G206D Mutation of Presenilin-1 Reduces Pen2 Interaction, Increases Aβ42/Aβ40 Ratio and Elevates ER Ca(2+) Accumulation.
Chen WT; Hsieh YF; Huang YJ; Lin CC; Lin YT; Liu YC; Lien CC; Cheng IH
Mol Neurobiol; 2015 Dec; 52(3):1835-1849. PubMed ID: 25394380
[TBL] [Abstract][Full Text] [Related]
4. Identification of new Presenilin-1 phosphosites: implication for γ-secretase activity and Aβ production.
Matz A; Halamoda-Kenzaoui B; Hamelin R; Mosser S; Alattia JR; Dimitrov M; Moniatte M; Fraering PC
J Neurochem; 2015 May; 133(3):409-21. PubMed ID: 25458374
[TBL] [Abstract][Full Text] [Related]
5. Bidirectional regulation of Aβ levels by Presenilin 1.
Bustos V; Pulina MV; Kelahmetoglu Y; Sinha SC; Gorelick FS; Flajolet M; Greengard P
Proc Natl Acad Sci U S A; 2017 Jul; 114(27):7142-7147. PubMed ID: 28533411
[TBL] [Abstract][Full Text] [Related]
6. Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.
Ye X; Feng T; Tammineni P; Chang Q; Jeong YY; Margolis DJ; Cai H; Kusnecov A; Cai Q
J Neurosci; 2017 Mar; 37(10):2639-2655. PubMed ID: 28159908
[TBL] [Abstract][Full Text] [Related]
7. Intracellular trafficking of presenilin 1 is regulated by beta-amyloid precursor protein and phospholipase D1.
Liu Y; Zhang YW; Wang X; Zhang H; You X; Liao FF; Xu H
J Biol Chem; 2009 May; 284(18):12145-52. PubMed ID: 19276086
[TBL] [Abstract][Full Text] [Related]
8. γ-Secretase complexes containing caspase-cleaved presenilin-1 increase intracellular Aβ(42) /Aβ(40) ratio.
Hedskog L; Petersen CA; Svensson AI; Welander H; Tjernberg LO; Karlström H; Ankarcrona M
J Cell Mol Med; 2011 Oct; 15(10):2150-63. PubMed ID: 21054783
[TBL] [Abstract][Full Text] [Related]
9. Dynamic Nature of presenilin1/γ-Secretase: Implication for Alzheimer's Disease Pathogenesis.
Zoltowska KM; Berezovska O
Mol Neurobiol; 2018 Mar; 55(3):2275-2284. PubMed ID: 28332150
[TBL] [Abstract][Full Text] [Related]
10. Oxidative stress up-regulates presenilin 1 in lipid rafts in neuronal cells.
Oda A; Tamaoka A; Araki W
J Neurosci Res; 2010 Apr; 88(5):1137-45. PubMed ID: 19885829
[TBL] [Abstract][Full Text] [Related]
11. Increased expression of PS1 is sufficient to elevate the level and activity of γ-secretase in vivo.
Li T; Li YM; Ahn K; Price DL; Sisodia SS; Wong PC
PLoS One; 2011; 6(11):e28179. PubMed ID: 22140537
[TBL] [Abstract][Full Text] [Related]
12. Human tau increases amyloid β plaque size but not amyloid β-mediated synapse loss in a novel mouse model of Alzheimer's disease.
Jackson RJ; Rudinskiy N; Herrmann AG; Croft S; Kim JM; Petrova V; Ramos-Rodriguez JJ; Pitstick R; Wegmann S; Garcia-Alloza M; Carlson GA; Hyman BT; Spires-Jones TL
Eur J Neurosci; 2016 Dec; 44(12):3056-3066. PubMed ID: 27748574
[TBL] [Abstract][Full Text] [Related]
13. Failure of the interaction between presenilin 1 and the substrate of gamma-secretase to produce Abeta in insect cells.
Pitsi D; Kienlen-Campard P; Octave JN
J Neurochem; 2002 Oct; 83(2):390-9. PubMed ID: 12423249
[TBL] [Abstract][Full Text] [Related]
14. Presenilin 1 is involved in the maturation of beta-site amyloid precursor protein-cleaving enzyme 1 (BACE1).
Kuzuya A; Uemura K; Kitagawa N; Aoyagi N; Kihara T; Ninomiya H; Ishiura S; Takahashi R; Shimohama S
J Neurosci Res; 2007 Jan; 85(1):153-65. PubMed ID: 17075903
[TBL] [Abstract][Full Text] [Related]
15. Monoamine oxidase B is elevated in Alzheimer disease neurons, is associated with γ-secretase and regulates neuronal amyloid β-peptide levels.
Schedin-Weiss S; Inoue M; Hromadkova L; Teranishi Y; Yamamoto NG; Wiehager B; Bogdanovic N; Winblad B; Sandebring-Matton A; Frykman S; Tjernberg LO
Alzheimers Res Ther; 2017 Aug; 9(1):57. PubMed ID: 28764767
[TBL] [Abstract][Full Text] [Related]
16. Conditional inactivation of nicastrin restricts amyloid deposition in an Alzheimer's disease mouse model.
Sesele K; Thanopoulou K; Paouri E; Tsefou E; Klinakis A; Georgopoulos S
Aging Cell; 2013 Dec; 12(6):1032-40. PubMed ID: 23826707
[TBL] [Abstract][Full Text] [Related]
17. Lack of tau proteins rescues neuronal cell death and decreases amyloidogenic processing of APP in APP/PS1 mice.
Leroy K; Ando K; Laporte V; Dedecker R; Suain V; Authelet M; Héraud C; Pierrot N; Yilmaz Z; Octave JN; Brion JP
Am J Pathol; 2012 Dec; 181(6):1928-40. PubMed ID: 23026200
[TBL] [Abstract][Full Text] [Related]
18. Rab21, a Novel PS1 Interactor, Regulates γ-Secretase Activity via PS1 Subcellular Distribution.
Sun Z; Xie Y; Chen Y; Yang Q; Quan Z; Dai R; Qing H
Mol Neurobiol; 2018 May; 55(5):3841-3855. PubMed ID: 28547526
[TBL] [Abstract][Full Text] [Related]
19. Immature nicastrin stabilizes APH-1 independent of PEN-2 and presenilin: identification of nicastrin mutants that selectively interact with APH-1.
Shirotani K; Edbauer D; Kostka M; Steiner H; Haass C
J Neurochem; 2004 Jun; 89(6):1520-7. PubMed ID: 15189355
[TBL] [Abstract][Full Text] [Related]
20. Neuronal activity and secreted amyloid β lead to altered amyloid β precursor protein and presenilin 1 interactions.
Li X; Uemura K; Hashimoto T; Nasser-Ghodsi N; Arimon M; Lill CM; Palazzolo I; Krainc D; Hyman BT; Berezovska O
Neurobiol Dis; 2013 Feb; 50():127-34. PubMed ID: 23064434
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]